ClinVar Genomic variation as it relates to human health
NM_006939.4(SOS2):c.1306G>A (p.Gly436Arg)
Germline
Classification
(1)
Uncertain significance
no assertion criteria provided
Somatic
No data submitted for somatic clinical impact
Somatic
No data submitted for oncogenicity
Genes
Gene | OMIM | ClinGen Gene Dosage Sensitivity Curation | Variation Viewer | Related variants | ||
---|---|---|---|---|---|---|
HI score | TS score | Within gene | All | |||
SOS2 | - | - |
GRCh38 GRCh37 |
1532 | 1583 |
Conditions - Germline
Condition | Classification
(# of submissions) |
Review status | Last evaluated | Variation/condition record |
---|---|---|---|---|
SOS2-related disorder
|
Uncertain significance (1) |
|
Feb 25, 2024 | RCV003982550.2 |
Citations for germline classification of this variant
HelpText-mined citations for this variant ...
HelpRecord last updated Oct 13, 2024