ClinVar

NM_004985.5(KRAS):c.40G>A (p.Val14Ile)

Gene:

KRAS:KRAS proto-oncogene, GTPase [Gene - OMIM - HGNC]

Variant type:

single nucleotide variant

Cytogenetic location:

12p12.1

Genomic location:

• Chr12: 25245345 (on Assembly GRCh38)
• Chr12: 25398279 (on Assembly GRCh37)

Preferred name:

NM_004985.5(KRAS):c.40G>A (p.Val14Ile)

Other names:

p.V14I:GTA>ATA; NM_004985.4(KRAS):c.40G>A

HGVS:

• NC_000012.12:g.25245345C>T
• NG_007524.2:g.10659G>A
• NM_001369786.1:c.40G>A
• NM_001369787.1:c.40G>A
• NM_004985.5:c.40G>AMANE SELECT
• NM_033360.4:c.40G>A
• NP_001356715.1:p.Val14Ile
• NP_001356716.1:p.Val14Ile
• NP_004976.2:p.Val14Ile
• NP_203524.1:p.Val14Ile
• LRG_344t1:c.40G>A
• LRG_344t2:c.40G>A
• LRG_344:g.10659G>A
• LRG_344p1:p.Val14Ile
• LRG_344p2:p.Val14Ile
• NC_000012.11:g.25398279C>T
• NG_007524.1:g.10576G>A
• NM_004985.3:c.40G>A
• NM_004985.4:c.40G>A
• NM_033360.2:c.40G>A
• NM_033360.3:c.40G>A
• P01116:p.Val14Ile

This HGVS expression did not pass validation

Protein change:

V14I; VAL14ILE

Links:

UniProtKB: P01116#VAR_026109; OMIM: 190070.0012; dbSNP: rs104894365

NCBI 1000 Genomes Browser:

rs104894365

Molecular consequence:

• NM_001369786.1:c.40G>A - missense variant - [Sequence Ontology: SO:0001583]
• NM_001369787.1:c.40G>A - missense variant - [Sequence Ontology: SO:0001583]
• NM_004985.5:c.40G>A - missense variant - [Sequence Ontology: SO:0001583]
• NM_033360.4:c.40G>A - missense variant - [Sequence Ontology: SO:0001583]