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Items: 16

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
SZT2
(C2481Y +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
DNMT3A
(R693H +3 more)
Single nucleotide variant
(missense variant +1 more)
Tatton-Brown-Rahman overgrowth syndrome
+7 more
GPathogenic/Likely pathogenic
STier II - Potential
OOncogenic
FGFR3
(P250R)
Single nucleotide variant
(missense variant +1 more)
Achondroplasia
+26 more
GPathogenic/Likely pathogenic
SLC22A5
Single nucleotide variant
(missense variant)
not provided
+3 more
GConflicting classifications of pathogenicity
COL11A2
(T323fs)
Duplication
(frameshift variant +1 more)
Short long bone
+8 more
GPathogenic/Likely pathogenic
SLC26A4
(R409H)
Single nucleotide variant
(missense variant)
Pendred syndrome
+5 more
GPathogenic/Likely pathogenic
BSCL2, HNRNPUL2-BSCL2
(N88S +1 more)
Single nucleotide variant
(non-coding transcript variant +1 more)
not specified
+8 more
GPathogenic
FBN1
(C2470F)
Single nucleotide variant
(missense variant)
Marfan syndrome
GLikely pathogenic
POLG
(P587L)
Single nucleotide variant
(missense variant)
Mitochondrial disease
+15 more
GConflicting classifications of pathogenicity
POLG
(T251I)
Single nucleotide variant
(missense variant)
POLG-Related Spectrum Disorders
+16 more
GConflicting classifications of pathogenicity
MYO15A
(R2146W)
Single nucleotide variant
(missense variant)
not provided
+2 more
GConflicting classifications of pathogenicity
NF1
(R1534* +1 more)
Single nucleotide variant
(nonsense)
Abnormality of the skin
+8 more
GPathogenic/Likely pathogenic
NF1
(R2496* +1 more)
Single nucleotide variant
(nonsense)
Juvenile myelomonocytic leukemia
+9 more
GPathogenic
CACNA1A
(R2135C +3 more)
Single nucleotide variant
(missense variant)
Cerebellar ataxia
+5 more
GConflicting classifications of pathogenicity
RYR1
(N4806D +1 more)
Single nucleotide variant
(missense variant)
RYR1-related disorder
+4 more
GPathogenic/Likely pathogenic
PLA2G6
(A401V +4 more)
Single nucleotide variant
(missense variant)
not specified
+4 more
GConflicting classifications of pathogenicity
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