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Items: 32

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
MTOR
(E1799K)
Single nucleotide variant
(missense variant)
CEBALID syndrome
+5 more
GPathogenic
SLC2A1
(I287L)
Single nucleotide variant
(missense variant)
Intellectual disability
GPathogenic
GJC2
(I36fs)
Deletion
(frameshift variant)
Intellectual disability
+2 more
GConflicting classifications of pathogenicity
SPR
Single nucleotide variant
(splice acceptor variant)
Intellectual disability
GPathogenic
CLASP1, RNU4ATAC
Single nucleotide variant
(intron variant)
Roifman syndrome
+5 more
GPathogenic/Likely pathogenic
SATB2
(R459*)
Single nucleotide variant
(nonsense)
Neurodevelopmental disorder
+4 more
GPathogenic
BCS1L
(R90C)
Single nucleotide variant
(missense variant +3 more)
Mitochondrial complex III deficiency nuclear type 1
+3 more
GPathogenic/Likely pathogenic
BCS1L
(G173D +2 more)
Single nucleotide variant
(missense variant +1 more)
Intellectual disability
+2 more
GConflicting classifications of pathogenicity
TRIP12
(R1561* +11 more)
Single nucleotide variant
(nonsense)
not provided
GPathogenic/Likely pathogenic
SETD5
(T628fs +1 more)
Microsatellite
(frameshift variant)
Intellectual disability-facial dysmorphism syndrome due to SETD5 haploinsufficiency
+1 more
GPathogenic
SLC6A1
(A214T +2 more)
Single nucleotide variant
(missense variant)
Myoclonic-atonic epilepsy
GLikely pathogenic
DHX30
(H562R +2 more)
Single nucleotide variant
(missense variant)
Sleep abnormality
+6 more
GPathogenic
PURA
(L54fs)
Duplication
(frameshift variant)
PURA-related severe neonatal hypotonia-seizures-encephalopathy syndrome due to a point mutation
+2 more
GPathogenic
WASF1
(Q520*)
Single nucleotide variant
(nonsense)
Epileptic encephalopathy
+2 more
GPathogenic
WASF1
(R506*)
Single nucleotide variant
(nonsense)
not provided
+1 more
GPathogenic
WASF1
(I494fs)
Indel
(frameshift variant)
Neurodevelopmental disorder with absent language and variable seizures
+1 more
GPathogenic
CAMK2B
(P139L)
Single nucleotide variant
(missense variant)
Intellectual disability, autosomal dominant 54
+3 more
GPathogenic/Likely pathogenic
VPS13B
Single nucleotide variant
(splice donor variant)
Cohen syndrome
GPathogenic
VPS13B
(V3903fs +1 more)
Duplication
(frameshift variant)
Myopia
+7 more
GLikely pathogenic
KIAA0586
(R131fs +3 more)
Deletion
(frameshift variant)
Retinal dystrophy
+5 more
GPathogenic/Likely pathogenic
KIAA0586
(Q150fs +5 more)
Deletion
(frameshift variant)
Joubert syndrome 23
+3 more
GPathogenic
ANKRD11
(R1462fs)
Duplication
(frameshift variant)
See cases
+3 more
GPathogenic
ANKRD11
(K635fs)
Microsatellite
(frameshift variant)
not provided
+11 more
GPathogenic/Likely pathogenic
SPG7
(A510V)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+10 more
GPathogenic/Likely pathogenic
SPG7
(Q664del)
Deletion
(inframe_deletion)
Intellectual disability
GLikely pathogenic
KIF1C
(N351fs)
Deletion
(frameshift variant)
Intellectual disability
GPathogenic
KCNB1
(R306C)
Single nucleotide variant
(missense variant)
not provided
+3 more
GPathogenic
DYRK1A
(R205* +2 more)
Single nucleotide variant
(nonsense)
not provided
+3 more
GPathogenic
SHANK3
(C599*)
Single nucleotide variant
(nonsense)
Abnormal cerebral white matter morphology
+3 more
GLikely pathogenic
KDM5C
(Q237* +2 more)
Single nucleotide variant
(nonsense +1 more)
Intellectual disability
GLikely pathogenic
GRIA3
(T776M)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GConflicting classifications of pathogenicity
MECP2
(A140V +2 more)
Single nucleotide variant
(missense variant +1 more)
Autism, susceptibility to, X-linked 3
+15 more
GPathogenic/Likely pathogenic
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