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Items: 72

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
SLC2A1
Single nucleotide variant
(splice acceptor variant)
not provided
GPathogenic
POGZ
(F1009fs +4 more)
Deletion
(frameshift variant)
not provided
GPathogenic
POGZ
(P136fs +1 more)
Deletion
(frameshift variant +1 more)
not provided
GPathogenic
GATAD2B
(Q220*)
Single nucleotide variant
(nonsense)
Severe intellectual disability-poor language-strabismus-grimacing face-long fingers syndrome
+1 more
GPathogenic
KCNH1
(R357Q +1 more)
Single nucleotide variant
(missense variant)
KCNH1-related disorder
+4 more
GPathogenic/Likely pathogenic
ZEB2
(R1016* +1 more)
Single nucleotide variant
(nonsense)
Mowat-Wilson syndrome
+2 more
GPathogenic/Likely pathogenic
ZEB2
(C961fs +1 more)
Deletion
(frameshift variant)
not provided
GPathogenic
SCN2A
(I1281T)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
TRIP12
(R1185fs +8 more)
Deletion
(frameshift variant)
not provided
GPathogenic
SETD5
Deletion
(frameshift variant)
not provided
GPathogenic
SLC6A1
(G297R +2 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GPathogenic/Likely pathogenic
SETD2
(E1941del +1 more)
Deletion
(inframe_deletion +1 more)
not provided
GLikely benign
FOXP1
Single nucleotide variant
(synonymous variant +1 more)
not provided
GPathogenic
NIPBL
(L2792fs)
Deletion
(3 prime UTR variant +1 more)
not provided
GPathogenic
SYNGAP1
(Q216*)
Single nucleotide variant
(nonsense)
not provided
GPathogenic
ARID1B
(E1751fs +3 more)
Deletion
(frameshift variant)
not provided
GPathogenic
STXBP1
Single nucleotide variant
(splice donor variant)
not provided
GPathogenic
STXBP1
Single nucleotide variant
(splice donor variant)
not provided
+2 more
GPathogenic/Likely pathogenic
SPTAN1
(W2274R +8 more)
Single nucleotide variant
(missense variant)
not provided
GLikely pathogenic
GATA3
(M400fs +1 more)
Deletion
(frameshift variant)
not provided
GPathogenic/Likely pathogenic
EIF3F
(F232V)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder
+5 more
GPathogenic/Likely pathogenic
VPS51
(R490C)
Single nucleotide variant
(missense variant +1 more)
not provided
GPathogenic
SHANK2
(P148fs +2 more)
Deletion
(frameshift variant +1 more)
not provided
GPathogenic
KMT2A
(T797fs)
Duplication
(frameshift variant)
not provided
GPathogenic
KMT2A
(A1750fs +1 more)
Duplication
(frameshift variant)
not provided
GPathogenic
KMT2A
(R1808* +1 more)
Single nucleotide variant
(nonsense)
not provided
+1 more
GPathogenic/Likely pathogenic
KMT2A
(Q3143* +1 more)
Single nucleotide variant
(nonsense)
not provided
GPathogenic
CACNA1C
(P312L +1 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
GRIN2B
(R682C)
Single nucleotide variant
(missense variant)
not provided
+2 more
GPathogenic/Likely pathogenic
GRIN2B
(Y646C)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 27
+1 more
GConflicting classifications of pathogenicity
GRIN2B
(L465V)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
KMT2D
(C2436fs)
Deletion
(frameshift variant)
not provided
GPathogenic
SCN8A
(R1597C +1 more)
Single nucleotide variant
(missense variant)
Seizure
+4 more
GConflicting classifications of pathogenicity
STAC3
(W284S +2 more)
Single nucleotide variant
(missense variant +1 more)
Bailey-Bloch congenital myopathy
+1 more
GPathogenic/Likely pathogenic
MAGEL2
(Q613*)
Single nucleotide variant
(nonsense)
not provided
GPathogenic
GABRB3
(Y217C +2 more)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 43
+3 more
GPathogenic/Likely pathogenic
FBN1
(Y2600*)
Single nucleotide variant
(nonsense)
Marfan syndrome
+1 more
GPathogenic/Likely pathogenic
FBN1
Deletion
(frameshift variant)
Marfan syndrome
+4 more
GPathogenic
ACAN
(G756R)
Single nucleotide variant
(missense variant)
not provided
GLikely pathogenic
TBC1D24
(L186fs)
Deletion
(frameshift variant)
not provided
GPathogenic
TBC1D24
(R435C +1 more)
Single nucleotide variant
(missense variant)
Autosomal dominant nonsyndromic hearing loss 65
+4 more
GConflicting classifications of pathogenicity
CDH15
(P439fs)
Deletion
(frameshift variant)
not provided
GUncertain significance
ANKRD11
(D851fs)
Deletion
(frameshift variant)
not provided
GPathogenic
ANKRD11
(R733*)
Single nucleotide variant
(nonsense)
KBG syndrome
+2 more
GPathogenic/Likely pathogenic
KANSL1
(R592W)
Single nucleotide variant
(missense variant)
not provided
+1 more
GConflicting classifications of pathogenicity
KANSL1
(L263fs)
Deletion
(frameshift variant)
not provided
GPathogenic
TLK2
(G459A +4 more)
Single nucleotide variant
(missense variant)
not provided
GLikely pathogenic
SEMA6B
(V183L)
Single nucleotide variant
(missense variant)
not provided
GLikely pathogenic
KCNB1
(S517*)
Single nucleotide variant
(nonsense)
not provided
GPathogenic
KCNQ2
(R144Q)
Single nucleotide variant
(missense variant)
Early infantile epileptic encephalopathy with suppression bursts
+3 more
GPathogenic/Likely pathogenic
ADSL
(R141W +1 more)
Single nucleotide variant
(missense variant +1 more)
Generalized myoclonic seizure
+6 more
GPathogenic/Likely pathogenic
ADSL
(R426H +1 more)
Single nucleotide variant
(missense variant +2 more)
Adenylosuccinate lyase deficiency
+2 more
GPathogenic
SHANK3
(D1469fs)
Deletion
(frameshift variant)
not provided
GPathogenic
FRMPD4
(E1018G +5 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
FRMPD4
(Q1241E +5 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
USP9X
(F1020fs)
Microsatellite
(frameshift variant)
not provided
GPathogenic
DDX3X
(D40fs +1 more)
Duplication
(frameshift variant +2 more)
not provided
GPathogenic
CASK
(V808M +4 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
NDP, NDP-AS1
(R90H)
Single nucleotide variant
(non-coding transcript variant +1 more)
Hearing impairment
+2 more
GConflicting classifications of pathogenicity
KDM6A
Deletion
(splice acceptor variant +2 more)
not provided
GPathogenic
FTSJ1
(W21fs)
Microsatellite
(frameshift variant +1 more)
not provided
GPathogenic
IQSEC2
(E1167*)
Single nucleotide variant
(nonsense +1 more)
not provided
GPathogenic
OPHN1
(G2V)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DLG3
(T145A +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
BRWD3
(N142H)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
FMR1
(G449S +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
HCFC1
Single nucleotide variant
(intron variant)
not provided
GUncertain significance
MECP2
(R309W +3 more)
Single nucleotide variant
(missense variant)
Rett syndrome
GPathogenic
MECP2
(G176fs +3 more)
Deletion
(frameshift variant)
Rett syndrome
GPathogenic
MECP2
(A140V +2 more)
Single nucleotide variant
(missense variant +1 more)
Autism, susceptibility to, X-linked 3
+15 more
GPathogenic/Likely pathogenic
MECP2
(R106Q +2 more)
Single nucleotide variant
(missense variant +1 more)
Rett syndrome
+3 more
GPathogenic/Likely pathogenic
FAM50A
(A244S)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
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