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Items: 29

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
PEX6
(A868T +1 more)
Single nucleotide variant
(missense variant +1 more)
Peroxisome biogenesis disorder
+1 more
GUncertain significance
PEX6
Single nucleotide variant
(splice donor variant)
Heimler syndrome 2
+2 more
GLikely pathogenic
PEX6
(A824V +1 more)
Single nucleotide variant
(missense variant +1 more)
See cases
+4 more
GPathogenic/Likely pathogenic
PEX6
(R876W +1 more)
Single nucleotide variant
(missense variant +1 more)
Heimler syndrome 2
+3 more
GConflicting classifications of pathogenicity
PEX6
(R726fs +1 more)
Duplication
(frameshift variant +1 more)
Heimler syndrome 2
+2 more
GLikely pathogenic
PEX6
(R814* +1 more)
Single nucleotide variant
(nonsense +1 more)
Heimler syndrome 2
+4 more
GPathogenic
PEX6
(R812Q +1 more)
Single nucleotide variant
(missense variant +1 more)
Heimler syndrome 2
+4 more
GPathogenic/Likely pathogenic
PEX6
Single nucleotide variant
(splice donor variant)
Heimler syndrome 2
+3 more
GLikely pathogenic
PEX6
(V788M +1 more)
Single nucleotide variant
(missense variant)
Heimler syndrome 2
+4 more
GConflicting classifications of pathogenicity
PEX6
(R786W +1 more)
Single nucleotide variant
(missense variant)
Heimler syndrome 2
+4 more
GConflicting classifications of pathogenicity
PEX6
(G607fs +1 more)
Deletion
(frameshift variant +1 more)
Heimler syndrome 2
+4 more
GPathogenic/Likely pathogenic
PEX6
(E664D +1 more)
Single nucleotide variant
(missense variant +1 more)
Peroxisome biogenesis disorder
+3 more
GConflicting classifications of pathogenicity
PEX6
Single nucleotide variant
(splice acceptor variant)
Heimler syndrome 2
+3 more
GPathogenic/Likely pathogenic
PEX6
(I562fs +1 more)
Deletion
(frameshift variant +1 more)
Heimler syndrome 2
+4 more
GPathogenic/Likely pathogenic
PEX6
(L526fs +1 more)
Deletion
(frameshift variant +1 more)
not provided
+5 more
GPathogenic/Likely pathogenic
PEX6
(R601Q +1 more)
Single nucleotide variant
(missense variant +1 more)
Peroxisome biogenesis disorder
+7 more
GConflicting classifications of pathogenicity
PEX6
(T572I +1 more)
Single nucleotide variant
(missense variant +1 more)
Peroxisome biogenesis disorder 4A (Zellweger)
+3 more
GPathogenic/Likely pathogenic
PEX6
(E439fs +1 more)
Deletion
(frameshift variant +1 more)
Peroxisome biogenesis disorder 4A (Zellweger)
+4 more
GPathogenic
PEX6
(P274L)
Single nucleotide variant
(missense variant +2 more)
Peroxisome biogenesis disorder 4A (Zellweger)
+5 more
GPathogenic/Likely pathogenic
PEX6
(D268fs)
Deletion
(frameshift variant +2 more)
Heimler syndrome 2
+3 more
GPathogenic
PEX6
(G220V)
Single nucleotide variant
(missense variant +2 more)
Heimler syndrome 2
+4 more
GConflicting classifications of pathogenicity
PEX6
(S173fs)
Deletion
(frameshift variant +1 more)
Peroxisome biogenesis disorder
+3 more
GPathogenic
PEX6
(E169fs)
Microsatellite
(frameshift variant +1 more)
Heimler syndrome 2
+3 more
GPathogenic/Likely pathogenic
PEX6
(P136fs)
Indel
(frameshift variant +1 more)
Heimler syndrome 2
+2 more
GLikely pathogenic
PEX6
(G104fs)
Deletion
(frameshift variant +1 more)
Heimler syndrome 2
+4 more
GPathogenic/Likely pathogenic
PEX6
Duplication
(inframe_insertion +1 more)
Heimler syndrome 2
+3 more
GUncertain significance
PEX6
(W91*)
Single nucleotide variant
(nonsense +1 more)
Heimler syndrome 2
+3 more
GPathogenic/Likely pathogenic
PEX6
(E15fs)
Duplication
(frameshift variant +1 more)
Heimler syndrome 2
+2 more
GLikely pathogenic
PEX6
(F12S)
Single nucleotide variant
(missense variant +1 more)
Peroxisome biogenesis disorder
+3 more
GConflicting classifications of pathogenicity
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