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Items: 36

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
PACS2
(E209K +1 more)
Single nucleotide variant
(missense variant)
not provided
+5 more
GPathogenic/Likely pathogenic
TBC1D24
(V73M)
Single nucleotide variant
(missense variant)
not provided
+9 more
GUncertain significance
TBC1D24
(D147N)
Single nucleotide variant
(missense variant)
Autosomal dominant nonsyndromic hearing loss 65
+9 more
GUncertain significance
TBC1D24
(S202L)
Single nucleotide variant
(missense variant)
not provided
+8 more
GUncertain significance
TBC1D24
(R270C)
Single nucleotide variant
(missense variant)
not provided
+8 more
GUncertain significance
TBC1D24
(A291T)
Single nucleotide variant
(missense variant)
Autosomal dominant nonsyndromic hearing loss 65
+9 more
GUncertain significance
TBC1D24
(R293H)
Single nucleotide variant
(missense variant)
not provided
+10 more
GUncertain significance
TBC1D24
Single nucleotide variant
(intron variant)
not specified
+9 more
GBenign/Likely benign
TBC1D24
Single nucleotide variant
(synonymous variant)
DOORS syndrome
+10 more
GBenign/Likely benign
TBC1D24
(P455fs +1 more)
Duplication
(frameshift variant)
DOORS syndrome
+8 more
GPathogenic/Likely pathogenic
TBC1D24
(A465T +1 more)
Single nucleotide variant
(missense variant)
Autosomal dominant nonsyndromic hearing loss 65
+7 more
GUncertain significance
TBC1D24
(A476D +1 more)
Single nucleotide variant
(missense variant)
Autosomal dominant nonsyndromic hearing loss 65
+10 more
GBenign/Likely benign
TBC1D24
Single nucleotide variant
(synonymous variant)
DOORS syndrome
+10 more
GBenign/Likely benign
TBC1D24
(I545V +1 more)
Single nucleotide variant
(missense variant)
Caused by mutation in the TBC1 domain family, member 24
+9 more
GUncertain significance
WWOX
(P20L)
Single nucleotide variant
(5 prime UTR variant +2 more)
Autosomal recessive spinocerebellar ataxia 12
+5 more
GUncertain significance
WWOX
(M114T +1 more)
Single nucleotide variant
(missense variant +2 more)
Autosomal recessive spinocerebellar ataxia 12
+4 more
GUncertain significance
WWOX
(A179S +1 more)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 28
+4 more
GConflicting classifications of pathogenicity
WWOX
(A179T +1 more)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 28
+5 more
GBenign
WWOX
(R188S +1 more)
Single nucleotide variant
(missense variant)
not provided
+4 more
GConflicting classifications of pathogenicity
WWOX
(F197L +1 more)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 28
+4 more
GUncertain significance
WWOX
(Q117P +1 more)
Single nucleotide variant
(missense variant)
Malignant tumor of esophagus
+7 more
GPathogenic/Likely pathogenic
WWOX
(R249H +1 more)
Single nucleotide variant
(missense variant)
not provided
+4 more
GUncertain significance
WWOX
(R264* +1 more)
Single nucleotide variant
(nonsense)
Developmental and epileptic encephalopathy, 1
+4 more
GPathogenic
WWOX
(R196H +1 more)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 1
+4 more
GUncertain significance
WWOX
(S312Y +1 more)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 1
+4 more
GUncertain significance
WWOX
(N330K +1 more)
Single nucleotide variant
(missense variant)
not provided
+4 more
GUncertain significance
WWOX
(P347T +1 more)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 28
+3 more
GUncertain significance
MAF, WWOX
Single nucleotide variant
(synonymous variant)
Developmental and epileptic encephalopathy, 1
+5 more
GBenign/Likely benign
MAF, WWOX
(R408Q +1 more)
Single nucleotide variant
(missense variant)
not provided
+5 more
GUncertain significance
ARX
(L484F)
Single nucleotide variant
(missense variant)
Partington syndrome
+5 more
GUncertain significance
ARX
Single nucleotide variant
(synonymous variant)
Developmental and epileptic encephalopathy, 1
+6 more
GConflicting classifications of pathogenicity
ARX
(R332G)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 1
+4 more
GPathogenic/Likely pathogenic
ARX
Single nucleotide variant
(synonymous variant)
Developmental and epileptic encephalopathy, 1
+6 more
GBenign/Likely benign
ARX, LOC109610631
Microsatellite
(inframe_deletion)
Developmental and epileptic encephalopathy, 1
+4 more
GUncertain significance
ARX
(R87P)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 1
+4 more
GUncertain significance
ARX
(A63T)
Single nucleotide variant
(missense variant)
not provided
+6 more
GConflicting classifications of pathogenicity
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