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Items: 93

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
APC, LOC129994371
Single nucleotide variant
(5 prime UTR variant +1 more)
Familial adenomatous polyposis 1
+4 more
GConflicting classifications of pathogenicity
APC
Single nucleotide variant
(5 prime UTR variant +1 more)
Familial adenomatous polyposis 1
+5 more
GUncertain significance
APC
Single nucleotide variant
(5 prime UTR variant +1 more)
Gastric adenocarcinoma and proximal polyposis of the stomach
+5 more
GUncertain significance
APC
Single nucleotide variant
(5 prime UTR variant +1 more)
Familial adenomatous polyposis 1
+5 more
GConflicting classifications of pathogenicity
APC
Single nucleotide variant
(5 prime UTR variant +1 more)
Familial adenomatous polyposis 1
+5 more
GUncertain significance
APC
Single nucleotide variant
(5 prime UTR variant +1 more)
Desmoid disease, hereditary
+5 more
GUncertain significance
APC
(M1V)
Single nucleotide variant
(missense variant +4 more)
Familial adenomatous polyposis 1
+5 more
GUncertain significance
APC
(R24*)
Single nucleotide variant
(nonsense +2 more)
Hereditary cancer-predisposing syndrome
+10 more
GConflicting classifications of pathogenicity
APC
(Q25fs)
Deletion
(frameshift variant +2 more)
Familial adenomatous polyposis 1
+7 more
GPathogenic
APC
(R71H +3 more)
Single nucleotide variant
(missense variant +1 more)
Classic or attenuated familial adenomatous polyposis
+9 more
GConflicting classifications of pathogenicity
APC
Single nucleotide variant
(intron variant)
Familial adenomatous polyposis 1
+5 more
GLikely benign
APC
Duplication
(intron variant)
Hereditary cancer-predisposing syndrome
+7 more
GBenign/Likely benign
APC
Deletion
(intron variant)
Familial adenomatous polyposis 1
GBenign
APC
Single nucleotide variant
(synonymous variant +1 more)
Familial adenomatous polyposis 1
+9 more
GBenign/Likely benign
APC
(R213* +3 more)
Single nucleotide variant
(nonsense +1 more)
Familial adenomatous polyposis 1
+8 more
GPathogenic
OOncogenic
APC
(Q215* +3 more)
Single nucleotide variant
(nonsense +1 more)
not specified
+8 more
GPathogenic
APC
(R216* +3 more)
Single nucleotide variant
(nonsense +2 more)
Classic or attenuated familial adenomatous polyposis
+9 more
GPathogenic
OOncogenic
APC
(R232* +3 more)
Single nucleotide variant
(nonsense +2 more)
Hereditary cancer-predisposing syndrome
+8 more
GPathogenic
OLikely oncogenic
APC
(R241Q +5 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+9 more
GUncertain significance
APC
(Q246R +5 more)
Single nucleotide variant
(missense variant +1 more)
Classic or attenuated familial adenomatous polyposis
+7 more
GConflicting classifications of pathogenicity
APC
(M253I +5 more)
Single nucleotide variant
(missense variant +1 more)
Gastric cancer
+9 more
GUncertain significance
APC
Single nucleotide variant
(intron variant)
Desmoid disease, hereditary
+6 more
GConflicting classifications of pathogenicity
APC
(R265* +5 more)
Single nucleotide variant
(nonsense +1 more)
Familial adenomatous polyposis 1
GPathogenic
APC
(D267G +6 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+8 more
GConflicting classifications of pathogenicity
APC
Single nucleotide variant
(splice donor variant)
Familial adenomatous polyposis 1
+5 more
GPathogenic/Likely pathogenic
APC
(R314* +6 more)
Single nucleotide variant
(nonsense +1 more)
Hereditary cancer-predisposing syndrome
+9 more
GPathogenic
APC
(K380R +6 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+9 more
GConflicting classifications of pathogenicity
APC
(R396H +10 more)
Single nucleotide variant
(missense variant)
not specified
+9 more
GConflicting classifications of pathogenicity
APC
Single nucleotide variant
(synonymous variant)
Familial adenomatous polyposis 1
GBenign
APC
Single nucleotide variant
(intron variant)
Familial adenomatous polyposis 1
+9 more
GPathogenic/Likely pathogenic
APC
(Q427E +10 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+7 more
GUncertain significance
APC
Single nucleotide variant
(synonymous variant)
Familial adenomatous polyposis 1
GBenign
APC
(V495A +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+7 more
GUncertain significance
APC
(T500M +12 more)
Single nucleotide variant
(missense variant)
not provided
+7 more
GConflicting classifications of pathogenicity
APC
(E518K +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+7 more
GConflicting classifications of pathogenicity
APC
(R554* +12 more)
Single nucleotide variant
(nonsense)
Hepatocellular carcinoma
+8 more
GPathogenic
APC
(V570I +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+9 more
GConflicting classifications of pathogenicity
APC
(S687N +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+7 more
GConflicting classifications of pathogenicity
APC
(M702I +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+6 more
GUncertain significance
APC
(Y807C +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+7 more
GConflicting classifications of pathogenicity
APC
(L808V +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
GBenign
APC
(I575T +12 more)
Single nucleotide variant
(missense variant)
not provided
+7 more
GUncertain significance
APC
(Y935* +12 more)
Single nucleotide variant
(nonsense)
Hepatocellular carcinoma
+8 more
GPathogenic
APC
(K987T +12 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+7 more
GUncertain significance
APC
(N1104S +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+8 more
GUncertain significance
APC
(I1164V +12 more)
Single nucleotide variant
(missense variant)
Gastric cancer
+6 more
GUncertain significance
APC
(R1153C +12 more)
Single nucleotide variant
(missense variant)
Gastric adenocarcinoma and proximal polyposis of the stomach
+9 more
GBenign/Likely benign
APC
(H1071L +12 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+6 more
GUncertain significance
APC
(P1203S +12 more)
Single nucleotide variant
(missense variant)
Desmoid disease, hereditary
+7 more
GConflicting classifications of pathogenicity
APC
(C1271* +12 more)
Single nucleotide variant
(nonsense)
Carcinoma of colon
+6 more
GPathogenic
APC
(T1200fs +12 more)
Duplication
(frameshift variant)
Hereditary cancer-predisposing syndrome
+8 more
GPathogenic/Likely pathogenic
APC
Single nucleotide variant
(synonymous variant)
not specified
+9 more
GBenign/Likely benign
APC
(Q1426H +12 more)
Single nucleotide variant
(missense variant)
Classic or attenuated familial adenomatous polyposis
+8 more
GConflicting classifications of pathogenicity
APC
(A1446T +12 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+8 more
GBenign/Likely benign
APC
(P1458S +12 more)
Single nucleotide variant
(missense variant)
Desmoid disease, hereditary
+8 more
GConflicting classifications of pathogenicity
APC
(P1467S +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
GBenign
APC
(Q1487R +12 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+6 more
GUncertain significance
APC
Single nucleotide variant
(synonymous variant)
Gastric cancer
+9 more
GBenign
APC
(N1263fs +12 more)
Deletion
(frameshift variant)
not provided
+6 more
GPathogenic/Likely pathogenic
APC
(K1598I +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+7 more
GUncertain significance
APC
(T1637A +12 more)
Single nucleotide variant
(missense variant)
Classic or attenuated familial adenomatous polyposis
+8 more
GConflicting classifications of pathogenicity
APC
(E1645K +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+7 more
GUncertain significance
APC
(A1653T +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+8 more
GUncertain significance
APC
(G1684E +12 more)
Single nucleotide variant
(missense variant)
not provided
+8 more
GConflicting classifications of pathogenicity
APC
Indel
(synonymous variant +1 more)
Hepatocellular carcinoma
+6 more
GBenign/Likely benign
APC
(N1743T +12 more)
Single nucleotide variant
(missense variant)
Classic or attenuated familial adenomatous polyposis
+8 more
GConflicting classifications of pathogenicity
APC
(R1770H +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+8 more
GConflicting classifications of pathogenicity
APC
(V1854D +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+7 more
GUncertain significance
APC
(R1858M +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+8 more
GConflicting classifications of pathogenicity
APC
(P1934L +12 more)
Single nucleotide variant
(missense variant)
not specified
+10 more
GConflicting classifications of pathogenicity
APC
(H1965P +12 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+9 more
GConflicting classifications of pathogenicity
APC
(G1947D +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+6 more
GUncertain significance
APC
(P2068R +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+5 more
GUncertain significance
APC
(M2195I +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+8 more
GConflicting classifications of pathogenicity
APC
(S2242G +12 more)
Single nucleotide variant
(missense variant)
Desmoid disease, hereditary
+9 more
GConflicting classifications of pathogenicity
APC
(T2225A +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+7 more
GUncertain significance
APC
(V2246I +12 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+7 more
GConflicting classifications of pathogenicity
APC
(A2274V +12 more)
Single nucleotide variant
(missense variant)
not provided
+10 more
GBenign/Likely benign
APC
(P2346S +12 more)
Single nucleotide variant
(missense variant)
Desmoid disease, hereditary
+8 more
GConflicting classifications of pathogenicity
APC
(Y2366C +12 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+6 more
GUncertain significance
APC
(P2351S +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+9 more
GConflicting classifications of pathogenicity
APC
(T2361S +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+8 more
GUncertain significance
APC
(S2371N +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+7 more
GUncertain significance
APC
(L2493F +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+8 more
GConflicting classifications of pathogenicity
APC
(S2586I +12 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+6 more
GUncertain significance
APC
(E2603G +12 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+7 more
GUncertain significance
APC
(P2489L +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+5 more
GUncertain significance
APC
(R2655G +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+8 more
GConflicting classifications of pathogenicity
APC
(R2741H +12 more)
Single nucleotide variant
(missense variant)
not provided
+8 more
GConflicting classifications of pathogenicity
APC
(P2761S +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+7 more
GUncertain significance
APC
(P2743L +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+8 more
GUncertain significance
APC
(S2779G +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+8 more
GConflicting classifications of pathogenicity
APC
(D2803G +12 more)
Single nucleotide variant
(missense variant)
Familial adenomatous polyposis 1
+8 more
GConflicting classifications of pathogenicity
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