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Items: 1 to 100 of 968

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
APC
(Q36*)
Single nucleotide variant
(nonsense +4 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(A4S)
Single nucleotide variant
(missense variant +2 more)
Classic or attenuated familial adenomatous polyposis
+2 more
GUncertain significance
APC
(S5L)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
+2 more
GUncertain significance
APC
(K11N)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
+1 more
GUncertain significance
APC
(E14V)
Single nucleotide variant
(intron variant +3 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(M18I)
Single nucleotide variant
(missense variant +2 more)
Classic or attenuated familial adenomatous polyposis
+2 more
GUncertain significance
APC
(L23V)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
APC
(R24*)
Single nucleotide variant
(nonsense +2 more)
Hereditary cancer-predisposing syndrome
+10 more
GConflicting classifications of pathogenicity
APC
(E28G)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(N32D)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
+1 more
GUncertain significance
APC
(T35K)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
APC
(A41V)
Single nucleotide variant
(missense variant +3 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(V57I +2 more)
Single nucleotide variant
(missense variant +1 more)
Classic or attenuated familial adenomatous polyposis
+3 more
GUncertain significance
APC
(K59fs +2 more)
Deletion
(frameshift variant +1 more)
not provided
+4 more
GPathogenic
APC
(K59T +2 more)
Single nucleotide variant
(missense variant +1 more)
Classic or attenuated familial adenomatous polyposis
+4 more
GUncertain significance
APC
(L61V +2 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(D32N +2 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
APC
(A59T +2 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
APC
(S38P +3 more)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(I76T +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+2 more
GUncertain significance
APC
(L9fs +3 more)
Deletion
(frameshift variant +1 more)
Familial adenomatous polyposis 1
+1 more
GPathogenic/Likely pathogenic
APC
(R71C +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+3 more
GUncertain significance
APC
Single nucleotide variant
(splice acceptor variant)
Familial adenomatous polyposis 1
+1 more
GPathogenic/Likely pathogenic
APC
(L16I +3 more)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(L18V +3 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
APC
(S21I +3 more)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(F82S +3 more)
Single nucleotide variant
(missense variant +1 more)
Desmoid disease, hereditary
+2 more
GUncertain significance
APC
(G84V +3 more)
Single nucleotide variant
(missense variant +1 more)
APC-related disorder
+3 more
GConflicting classifications of pathogenicity
APC
(L87P +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+1 more
GUncertain significance
APC
(R88Q +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+2 more
GConflicting classifications of pathogenicity
APC
(M32fs +3 more)
Deletion
(frameshift variant +1 more)
not provided
+2 more
GPathogenic/Likely pathogenic
OLikely oncogenic
APC
(K100E +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+4 more
GUncertain significance
APC
(M101I +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+1 more
GConflicting classifications of pathogenicity
APC
(S102C +3 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+2 more
GConflicting classifications of pathogenicity
APC
(R104S +3 more)
Single nucleotide variant
(missense variant +1 more)
Ovarian cancer
+3 more
GConflicting classifications of pathogenicity
APC
(R104H +3 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+4 more
GUncertain significance
APC
(Y106* +3 more)
Single nucleotide variant
(nonsense +1 more)
not provided
+3 more
GPathogenic
APC
(E100fs +3 more)
Deletion
(frameshift variant +1 more)
not provided
+1 more
GPathogenic/Likely pathogenic
APC
(R109Q +3 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+3 more
GConflicting classifications of pathogenicity
APC
(G101* +3 more)
Single nucleotide variant
(nonsense +1 more)
Familial adenomatous polyposis 1
+1 more
GPathogenic
APC
(S102P +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+2 more
GConflicting classifications of pathogenicity
APC
(S104* +3 more)
Single nucleotide variant
(nonsense +1 more)
Familial adenomatous polyposis 1
+3 more
GPathogenic/Likely pathogenic
APC
(S105G +3 more)
Single nucleotide variant
(missense variant +1 more)
Classic or attenuated familial adenomatous polyposis
+3 more
GUncertain significance
APC
(R116L +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+1 more
GUncertain significance
APC
(S111N +3 more)
Single nucleotide variant
(missense variant +1 more)
Classic or attenuated familial adenomatous polyposis
+3 more
GUncertain significance
APC
(M115V +3 more)
Single nucleotide variant
(missense variant +1 more)
Classic or attenuated familial adenomatous polyposis
+4 more
GUncertain significance
APC
(G116V +3 more)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(R121I +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+2 more
GConflicting classifications of pathogenicity
APC
(G132R +3 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
APC
(S127G +3 more)
Single nucleotide variant
(missense variant +1 more)
not specified
+4 more
GConflicting classifications of pathogenicity
APC
(S105C +3 more)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(T72A +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+1 more
GUncertain significance
APC
(T106I +3 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
APC
(E140D +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
GLikely benign
APC
(R82K +3 more)
Single nucleotide variant
(missense variant +1 more)
APC-Associated Polyposis Disorders
+2 more
GUncertain significance
APC
Deletion
(splice acceptor variant)
Familial adenomatous polyposis 1
GUncertain significance
APC
Single nucleotide variant
(intron variant)
Familial adenomatous polyposis 1
+2 more
GPathogenic/Likely pathogenic
APC
Single nucleotide variant
(splice acceptor variant)
Familial adenomatous polyposis 1
+1 more
GPathogenic
APC
(L143fs +3 more)
Deletion
(frameshift variant +1 more)
not provided
+5 more
GPathogenic
APC
(L119P +3 more)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
+1 more
GUncertain significance
APC
(A146V +3 more)
Single nucleotide variant
(missense variant +1 more)
not specified
+4 more
GUncertain significance
APC
(D122E +3 more)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(D149E +3 more)
Single nucleotide variant
(missense variant +1 more)
Classic or attenuated familial adenomatous polyposis
+2 more
GUncertain significance
APC
(K150R +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+4 more
GConflicting classifications of pathogenicity
APC
(K128Q +3 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
APC
(K153R +3 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
APC
(D156E +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+4 more
GConflicting classifications of pathogenicity
APC
(W132C +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+1 more
GUncertain significance
APC
(Y159* +3 more)
Duplication
(nonsense +1 more)
Hereditary cancer-predisposing syndrome
+2 more
GPathogenic/Likely pathogenic
APC
(Y159* +3 more)
Single nucleotide variant
(nonsense +1 more)
Familial adenomatous polyposis 1
+3 more
GPathogenic
APC
(R109fs +3 more)
Deletion
(frameshift variant +1 more)
Familial adenomatous polyposis 1
+1 more
GPathogenic/Likely pathogenic
APC
(D170fs +3 more)
Microsatellite
(frameshift variant +1 more)
Familial adenomatous polyposis 1
GPathogenic
APC
(I144T +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+2 more
GUncertain significance
APC
Single nucleotide variant
(splice donor variant)
Familial adenomatous polyposis 1
+2 more
GPathogenic/Likely pathogenic
APC
Single nucleotide variant
(splice acceptor variant)
not specified
+2 more
GPathogenic/Likely pathogenic
APC
(F178I +3 more)
Single nucleotide variant
(missense variant +1 more)
Classic or attenuated familial adenomatous polyposis
+4 more
GUncertain significance
APC
(R127G +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+2 more
GUncertain significance
APC
Indel
(missense variant +2 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(A199V +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+3 more
GUncertain significance
APC
(Q144K +3 more)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(Q203R +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
+3 more
GUncertain significance
APC
(D209N +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+2 more
GUncertain significance
APC
(E152G +3 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 1
GUncertain significance
APC
(R213* +3 more)
Single nucleotide variant
(nonsense +1 more)
Familial adenomatous polyposis 1
+8 more
GPathogenic
OOncogenic
APC
(Q215* +3 more)
Single nucleotide variant
(nonsense +1 more)
not specified
+8 more
GPathogenic
APC
Single nucleotide variant
(splice donor variant)
Hereditary cancer-predisposing syndrome
+1 more
GPathogenic/Likely pathogenic
APC
(R216* +3 more)
Single nucleotide variant
(nonsense +2 more)
Classic or attenuated familial adenomatous polyposis
+9 more
GPathogenic
OOncogenic
APC
(R216Q +3 more)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
+5 more
GConflicting classifications of pathogenicity
APC
(I159T +3 more)
Single nucleotide variant
(missense variant +3 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
APC
(Q223* +3 more)
Single nucleotide variant
(nonsense +2 more)
Familial multiple polyposis syndrome
+2 more
GPathogenic
APC
(Q223H +3 more)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
+4 more
GConflicting classifications of pathogenicity
APC
(I234M +3 more)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
+2 more
GUncertain significance
APC
(E225K +3 more)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
+2 more
GUncertain significance
APC
(D168G +3 more)
Single nucleotide variant
(missense variant +2 more)
Familial adenomatous polyposis 1
+2 more
GUncertain significance
APC
(I228V +3 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
APC
(R230C +3 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
APC
(R232* +3 more)
Single nucleotide variant
(nonsense +2 more)
Hereditary cancer-predisposing syndrome
+8 more
GPathogenic
OLikely oncogenic
APC
(R232Q +3 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
APC
Single nucleotide variant
(intron variant)
not provided
+2 more
GUncertain significance
APC
(G235C +5 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
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