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Items: 100

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
CEP290, RLIG1
(L2448fs)
Duplication
(frameshift variant +1 more)
Bardet-Biedl syndrome 14
+7 more
GPathogenic/Likely pathogenic
CEP290, RLIG1
(K2447fs)
Deletion
(frameshift variant +1 more)
not provided
+8 more
GPathogenic/Likely pathogenic
CEP290, RLIG1
(V2445fs)
Microsatellite
(frameshift variant +1 more)
Meckel-Gruber syndrome
+8 more
GPathogenic/Likely pathogenic
CEP290, RLIG1
(E2443fs)
Microsatellite
(frameshift variant +1 more)
Leber congenital amaurosis 10
+8 more
GPathogenic
CEP290, RLIG1
(Y2429*)
Duplication
(nonsense +1 more)
Familial aplasia of the vermis
+7 more
GPathogenic/Likely pathogenic
CEP290, RLIG1
(E2412fs)
Duplication
(frameshift variant +1 more)
Leber congenital amaurosis 10
+7 more
GPathogenic/Likely pathogenic
CEP290
(Q2400*)
Single nucleotide variant
(nonsense)
Bardet-Biedl syndrome 14
+8 more
GPathogenic/Likely pathogenic
CEP290
Deletion
(nonsense)
Bardet-Biedl syndrome 14
+7 more
GPathogenic/Likely pathogenic
CEP290
(V2343fs)
Deletion
(frameshift variant)
Joubert syndrome 5
+5 more
GPathogenic
CEP290
(Y2313*)
Single nucleotide variant
(nonsense)
Joubert syndrome 5
+1 more
GPathogenic
CEP290
(N2290fs)
Duplication
(frameshift variant)
Retinal dystrophy
+9 more
GPathogenic
CEP290
(N2290fs)
Deletion
(frameshift variant)
Joubert syndrome 5
+5 more
GPathogenic
CEP290
Duplication
(splice donor variant)
Familial aplasia of the vermis
+4 more
GLikely pathogenic
CEP290
(W2266*)
Single nucleotide variant
(nonsense)
Leber congenital amaurosis 10
+10 more
GPathogenic
CEP290
(A2251G)
Single nucleotide variant
(missense variant)
Nephronophthisis
+3 more
GUncertain significance
CEP290
Single nucleotide variant
(splice donor variant)
Inborn genetic diseases
+9 more
GConflicting classifications of pathogenicity
CEP290
(I2202fs)
Deletion
(frameshift variant)
Bardet-Biedl syndrome 14
+10 more
GPathogenic/Likely pathogenic
CEP290
(Q2150fs)
Deletion
(frameshift variant)
not provided
+8 more
GPathogenic/Likely pathogenic
CEP290
Single nucleotide variant
(splice acceptor variant)
Joubert syndrome 5
+7 more
GLikely pathogenic
CEP290, LOC129390514
Deletion
(frameshift variant)
Meckel-Gruber syndrome
+8 more
GPathogenic/Likely pathogenic
CEP290
Single nucleotide variant
(splice acceptor variant)
Joubert syndrome 5
+4 more
GPathogenic
CEP290
(R1978*)
Single nucleotide variant
(nonsense)
Joubert syndrome 5
+5 more
GPathogenic
CEP290
(F1950fs)
Deletion
(frameshift variant)
Bardet-Biedl syndrome 14
+7 more
GPathogenic
CEP290
(T1938fs)
Microsatellite
(frameshift variant)
not provided
+8 more
GPathogenic
CEP290
(K1930*)
Single nucleotide variant
(nonsense)
Retinal dystrophy
+5 more
GPathogenic
CEP290
(R1926P)
Single nucleotide variant
(missense variant)
Bardet-Biedl syndrome 14
+9 more
GPathogenic/Likely pathogenic
CEP290
(R1926*)
Single nucleotide variant
(nonsense)
Joubert syndrome 5
+5 more
GPathogenic/Likely pathogenic
CEP290
(G1890*)
Single nucleotide variant
(nonsense)
Meckel-Gruber syndrome
+13 more
GPathogenic/Likely pathogenic
CEP290
(L1884fs)
Duplication
(frameshift variant)
Familial aplasia of the vermis
+7 more
GPathogenic
CEP290
(Q1871fs)
Deletion
(frameshift variant)
Senior-Loken syndrome 6
+8 more
GPathogenic
CEP290
Single nucleotide variant
(splice acceptor variant)
Bardet-Biedl syndrome 14
+9 more
GPathogenic
CEP290
(A1832fs)
Deletion
(frameshift variant)
Polycystic kidney disease
+14 more
GPathogenic
CEP290
(R1782*)
Single nucleotide variant
(nonsense)
Bardet-Biedl syndrome 14
+8 more
GPathogenic
CEP290
Microsatellite
(splice donor variant)
Bardet-Biedl syndrome 14
+7 more
GUncertain significance
CEP290
Single nucleotide variant
(splice donor variant)
Bardet-Biedl syndrome 14
+8 more
GLikely pathogenic
CEP290
(E1656fs)
Microsatellite
(frameshift variant)
Bardet-Biedl syndrome 14
+4 more
GPathogenic
CEP290
(E1656fs)
Deletion
(frameshift variant)
Bardet-Biedl syndrome 14
+10 more
GPathogenic
CEP290
(Q1628*)
Single nucleotide variant
(nonsense)
Bardet-Biedl syndrome 14
+13 more
GPathogenic
CEP290
Single nucleotide variant
(splice acceptor variant)
Retinal dystrophy
+10 more
GPathogenic/Likely pathogenic
CEP290
(K1575*)
Single nucleotide variant
(nonsense)
CEP290-related ciliopathy
+13 more
GPathogenic
CEP290
Single nucleotide variant
(splice acceptor variant)
Joubert syndrome 5
+7 more
GPathogenic/Likely pathogenic
CEP290
(R1508*)
Single nucleotide variant
(nonsense)
not provided
+8 more
GPathogenic
CEP290
(K1484fs)
Microsatellite
(frameshift variant)
Retinal dystrophy
+6 more
GPathogenic
CEP290
(R1465*)
Single nucleotide variant
(nonsense)
Bardet-Biedl syndrome 14
+9 more
GPathogenic
CEP290
(E1462fs)
Deletion
(frameshift variant)
Joubert syndrome 5
+4 more
GPathogenic
CEP290
(I1393V)
Single nucleotide variant
(missense variant)
Bardet-Biedl syndrome 14
+4 more
GUncertain significance
CEP290
(K1343fs)
Deletion
(frameshift variant)
not provided
+8 more
GPathogenic/Likely pathogenic
CEP290
(Q1302*)
Single nucleotide variant
(nonsense)
Joubert syndrome 5
+4 more
GPathogenic
CEP290
(K1299*)
Duplication
(nonsense)
Joubert syndrome 5
+4 more
GPathogenic/Likely pathogenic
CEP290
(R1272*)
Single nucleotide variant
(nonsense)
Familial aplasia of the vermis
+8 more
GPathogenic
CEP290
(R1264C)
Single nucleotide variant
(missense variant)
Meckel syndrome, type 4
+11 more
GConflicting classifications of pathogenicity
CEP290
(R1237fs)
Duplication
(frameshift variant)
Meckel syndrome, type 4
+5 more
GPathogenic/Likely pathogenic
CEP290
(S1198L)
Single nucleotide variant
(missense variant)
Leber congenital amaurosis 10
+9 more
GUncertain significance
CEP290
(F1095fs)
Deletion
(frameshift variant)
Familial aplasia of the vermis
+7 more
GPathogenic/Likely pathogenic
CEP290
(L1062fs)
Deletion
(frameshift variant)
Bardet-Biedl syndrome 14
+4 more
GPathogenic
CEP290
(I1059fs)
Duplication
(frameshift variant)
Meckel-Gruber syndrome
+6 more
GPathogenic
CEP290
Deletion
(nonsense)
Senior-Loken syndrome 6
+7 more
GPathogenic
CEP290
Single nucleotide variant
(intron variant)
not provided
+12 more
GPathogenic/Likely pathogenic
CEP290
(Q981*)
Single nucleotide variant
(nonsense)
Blindness
+5 more
GPathogenic/Likely pathogenic
CEP290
(R908*)
Single nucleotide variant
(nonsense)
Bardet-Biedl syndrome 14
+10 more
GPathogenic
CEP290
(I878fs)
Deletion
(frameshift variant)
CEP290-related disorder
+8 more
GPathogenic/Likely pathogenic
CEP290
(L865fs)
Deletion
(frameshift variant)
not provided
+5 more
GPathogenic/Likely pathogenic
CEP290
(K797fs)
Deletion
(frameshift variant)
Leber congenital amaurosis 10
+9 more
GPathogenic
CEP290
(R751*)
Single nucleotide variant
(nonsense)
Familial aplasia of the vermis
+8 more
GPathogenic
CEP290
(V705fs)
Deletion
(frameshift variant)
not provided
+5 more
GPathogenic
CEP290
Deletion
(splice donor variant)
Leber congenital amaurosis 10
+9 more
GPathogenic
CEP290
(Q662*)
Single nucleotide variant
(nonsense)
Familial aplasia of the vermis
+8 more
GPathogenic
CEP290
(Q646*)
Single nucleotide variant
(nonsense)
Nephronophthisis
+9 more
GPathogenic
CEP290
(E639*)
Single nucleotide variant
(nonsense)
not provided
+8 more
GPathogenic/Likely pathogenic
CEP290
(E610fs)
Deletion
(frameshift variant)
Bardet-Biedl syndrome 14
+7 more
GPathogenic
CEP290
(L594*)
Single nucleotide variant
(nonsense)
Meckel syndrome, type 4
+8 more
GPathogenic
CEP290
Single nucleotide variant
(splice donor variant)
CEP290-related disorder
+9 more
GPathogenic/Likely pathogenic
CEP290
(I556fs)
Duplication
(frameshift variant)
Joubert syndrome 1
+8 more
GPathogenic
CEP290
(I556fs)
Deletion
(frameshift variant)
not provided
+10 more
GPathogenic
CEP290
(R549*)
Single nucleotide variant
(nonsense)
Senior-Loken syndrome 6
+8 more
GPathogenic
CEP290
Single nucleotide variant
(splice donor variant)
Bardet-Biedl syndrome 14
+5 more
GPathogenic
CEP290
(E505fs)
Microsatellite
(frameshift variant)
Joubert syndrome 5
+4 more
GPathogenic
CEP290
(R504fs)
Microsatellite
(frameshift variant)
not provided
+10 more
GPathogenic/Likely pathogenic
CEP290
(R477*)
Single nucleotide variant
(nonsense)
CEP290-related disorder
+9 more
GPathogenic/Likely pathogenic
CEP290
Single nucleotide variant
(splice donor variant)
Nephronophthisis
+7 more
GLikely pathogenic
CEP290
(K419fs)
Microsatellite
(frameshift variant)
Senior-Loken syndrome 6
+7 more
GPathogenic/Likely pathogenic
CEP290
(M407fs)
Microsatellite
(frameshift variant)
not provided
+10 more
GPathogenic
CEP290
Single nucleotide variant
(splice donor variant)
Familial aplasia of the vermis
+4 more
GPathogenic
CEP290
(R360*)
Single nucleotide variant
(nonsense)
Nephronophthisis
+8 more
GPathogenic
CEP290
Single nucleotide variant
(splice acceptor variant)
Bardet-Biedl syndrome 14
+8 more
GPathogenic
CEP290
(E277*)
Single nucleotide variant
(nonsense)
Nephronophthisis
+7 more
GPathogenic/Likely pathogenic
CEP290
(E277fs)
Deletion
(frameshift variant)
not provided
+9 more
GPathogenic
CEP290
(E238*)
Single nucleotide variant
(nonsense)
CEP290-related disorder
+9 more
GPathogenic
CEP290
(E227fs)
Deletion
(frameshift variant)
Familial aplasia of the vermis
+7 more
GPathogenic
CEP290
(R205*)
Single nucleotide variant
(nonsense)
Leber congenital amaurosis 10
+12 more
GPathogenic
CEP290
(L195fs)
Deletion
(frameshift variant)
Bardet-Biedl syndrome 14
+7 more
GPathogenic/Likely pathogenic
CEP290
(K170*)
Single nucleotide variant
(nonsense)
Retinal dystrophy
+9 more
GPathogenic
CEP290
(E146fs)
Deletion
(frameshift variant)
Bardet-Biedl syndrome 14
+8 more
GPathogenic
CEP290
(D128fs)
Deletion
(frameshift variant)
not provided
+10 more
GPathogenic
CEP290
(Q123fs)
Deletion
(frameshift variant)
Senior-Loken syndrome 6
+8 more
GPathogenic/Likely pathogenic
CEP290
(Q123*)
Single nucleotide variant
(nonsense)
Nephronophthisis
+8 more
GPathogenic
CEP290
(E97*)
Single nucleotide variant
(nonsense)
Meckel syndrome, type 4
+6 more
GPathogenic/Likely pathogenic
CEP290
(T55fs)
Deletion
(frameshift variant)
Leber congenital amaurosis
+9 more
GPathogenic
CEP290
Single nucleotide variant
(splice donor variant)
CEP290-related disorder
+8 more
GLikely pathogenic
CEP290
(M11V)
Single nucleotide variant
(missense variant)
Meckel syndrome, type 4
+8 more
GUncertain significance
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