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Items: 15

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
ASPM
(K2595fs)
Deletion
(frameshift variant +1 more)
Inborn genetic diseases
+3 more
GPathogenic
MCPH1
(K11N +2 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GUncertain significance
MCPH1
(K117E +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
MCPH1
(N187fs +2 more)
Duplication
(frameshift variant +2 more)
Microcephaly 1, primary, autosomal recessive
+1 more
GPathogenic
MCPH1
(R184C +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GConflicting classifications of pathogenicity
MCPH1
(C222R +3 more)
Single nucleotide variant
(missense variant +1 more)
Microcephaly 1, primary, autosomal recessive
+3 more
GConflicting classifications of pathogenicity
MCPH1
(V397M +3 more)
Single nucleotide variant
(missense variant +1 more)
Microcephaly 1, primary, autosomal recessive
+1 more
GUncertain significance
MCPH1
(Y367C +3 more)
Single nucleotide variant
(missense variant +1 more)
Microcephaly 1, primary, autosomal recessive
GUncertain significance
MCPH1
(E457K +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GUncertain significance
MCPH1
(E521* +3 more)
Single nucleotide variant
(nonsense +1 more)
not provided
+1 more
GConflicting classifications of pathogenicity
MCPH1
(R693C)
Single nucleotide variant
(missense variant +1 more)
Microcephaly 1, primary, autosomal recessive
+1 more
GUncertain significance
MCPH1
Deletion
(frameshift variant +1 more)
Microcephaly 1, primary, autosomal recessive
GLikely pathogenic
ANGPT2, MCPH1
(A737G)
Single nucleotide variant
(3 prime UTR variant +2 more)
not specified
+3 more
GUncertain significance
MCPH1, MCPH1-AS1
(R648* +1 more)
Single nucleotide variant
(non-coding transcript variant +1 more)
Microcephaly 1, primary, autosomal recessive
+1 more
GConflicting classifications of pathogenicity
CENPJ
(S7fs)
Deletion
(frameshift variant +1 more)
not provided
+1 more
GPathogenic
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