C1846862[trait identifier] AND "Fulgent Genetics, Fulgent Genetics"[su - ClinVar

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Items: 63

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 1622963	NM_198578.4(LRRK2):c.45T>C (p.Thr15=)	LRRK2	Single nucleotide variant (synonymous variant)	Autosomal dominant Parkinson disease 8 +1 more	GLikely benign
Select item 1397201	NM_198578.4(LRRK2):c.137C>T (p.Thr46Met)	LRRK2 (T46M)	Single nucleotide variant (missense variant)	Inborn genetic diseases +1 more	GUncertain significance
Select item 859873	NM_198578.4(LRRK2):c.309G>C (p.Gln103His)	LRRK2 (Q103H)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 1381407	NM_198578.4(LRRK2):c.500T>G (p.Met167Arg)	LRRK2 (M167R)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 39211	NM_198578.4(LRRK2):c.546A>G (p.Lys182=)	LRRK2	Single nucleotide variant (synonymous variant)	Autosomal dominant Parkinson disease 8 +1 more	GConflicting classifications of pathogenicity
Select item 39231	NM_198578.4(LRRK2):c.683G>C (p.Cys228Ser)	LRRK2 (C228S)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 308612	NM_198578.4(LRRK2):c.867C>T (p.Asn289=)	LRRK2	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign/Likely benign
Select item 39246	NM_198578.4(LRRK2):c.936G>T (p.Ala312=)	LRRK2	Single nucleotide variant (synonymous variant)	not provided +2 more	GBenign/Likely benign
Select item 579293	NM_198578.4(LRRK2):c.1240G>A (p.Val414Ile)	LRRK2 (V414I)	Single nucleotide variant (missense variant)	not provided +1 more	GUncertain significance
Select item 39131	NM_198578.4(LRRK2):c.1256C>T (p.Ala419Val)	LRRK2 (A419V)	Single nucleotide variant (missense variant)	not provided +1 more	GBenign/Likely benign
Select item 1493722	NM_198578.4(LRRK2):c.1324C>T (p.His442Tyr)	LRRK2 (H442Y)	Single nucleotide variant (missense variant)	Inborn genetic diseases +1 more	GConflicting classifications of pathogenicity
Select item 695715	NM_198578.4(LRRK2):c.1383T>C (p.Ser461=)	LRRK2	Single nucleotide variant (synonymous variant)	Autosomal dominant Parkinson disease 8 +2 more	GLikely benign
Select item 1406544	NM_198578.4(LRRK2):c.1546A>G (p.Met516Val)	LRRK2 (M516V)	Single nucleotide variant (missense variant)	Inborn genetic diseases +1 more	GConflicting classifications of pathogenicity
Select item 39139	NM_198578.4(LRRK2):c.1653C>G (p.Asn551Lys)	LRRK2 (N551K)	Single nucleotide variant (missense variant)	not provided +1 more	GBenign
Select item 1490259	NM_198578.4(LRRK2):c.1874A>G (p.His625Arg)	LRRK2 (H625R)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 39142	NM_198578.4(LRRK2):c.1987T>C (p.Ser663Pro)	LRRK2 (S663P)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 1545347	NM_198578.4(LRRK2):c.2229T>G (p.Ser743=)	LRRK2	Single nucleotide variant (synonymous variant)	Inborn genetic diseases +1 more	GLikely benign
Select item 39148	NM_198578.4(LRRK2):c.2264C>T (p.Pro755Leu)	LRRK2 (P755L)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8 +1 more	GBenign/Likely benign
Select item 934690	NM_198578.4(LRRK2):c.2333G>A (p.Ser778Asn)	LRRK2 (S778N)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8 +1 more	GUncertain significance
Select item 39151	NM_198578.4(LRRK2):c.2481T>C (p.Ser827=)	LRRK2	Single nucleotide variant (synonymous variant)	Autosomal dominant Parkinson disease 8 +1 more	GLikely benign
Select item 1610647	NM_198578.4(LRRK2):c.2689+19_2689+20dup	LRRK2	Duplication (intron variant)	Autosomal dominant Parkinson disease 8	GBenign/Likely benign
Select item 308619	NM_198578.4(LRRK2):c.2689+20dup	LRRK2	Duplication (intron variant)	Autosomal dominant Parkinson disease 8	GBenign/Likely benign
Select item 881646	NM_198578.4(LRRK2):c.2758G>A (p.Ala920Thr)	LRRK2 (A920T)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8 +1 more	GConflicting classifications of pathogenicity
Select item 804995	NM_198578.4(LRRK2):c.2771G>A (p.Arg924His)	LRRK2 (R924H)	Single nucleotide variant (missense variant)	not provided +1 more	GConflicting classifications of pathogenicity
Select item 39156	NM_198578.4(LRRK2):c.2857T>C (p.Leu953=)	LRRK2	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 39159	NM_198578.4(LRRK2):c.3018A>G (p.Ile1006Met)	LRRK2 (I1006M)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 1359114	NM_198578.4(LRRK2):c.3091T>C (p.Cys1031Arg)	LRRK2 (C1031R)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 39163	NM_198578.4(LRRK2):c.3333G>T (p.Gln1111His)	LRRK2 (Q1111H)	Single nucleotide variant (missense variant)	not provided +1 more	GBenign/Likely benign
Select item 308626	NM_198578.4(LRRK2):c.3497-8del	LRRK2	Deletion (intron variant)	not provided +1 more	GBenign/Likely benign
Select item 1439609	NM_198578.4(LRRK2):c.3595C>T (p.Arg1199Trp)	LRRK2 (R1199W)	Single nucleotide variant (missense variant)	Inborn genetic diseases +1 more	GUncertain significance
Select item 444287	NM_198578.4(LRRK2):c.3643G>A (p.Ala1215Thr)	LRRK2 (A1215T)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8 +1 more	GUncertain significance
Select item 308630	NM_198578.4(LRRK2):c.3778-9C>T	LRRK2	Single nucleotide variant (intron variant)	not provided +1 more	GBenign/Likely benign
Select item 39173	NM_198578.4(LRRK2):c.3784C>G (p.Pro1262Ala)	LRRK2 (P1262A)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8 +1 more	GBenign/Likely benign
Select item 1388424	NM_198578.4(LRRK2):c.4117G>A (p.Val1373Met)	LRRK2 (V1373M)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 39178	NM_198578.4(LRRK2):c.4193G>A (p.Arg1398His)	LRRK2 (R1398H)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8 +1 more	GBenign/Likely benign
Select item 39181	NM_198578.4(LRRK2):c.4269G>A (p.Lys1423=)	LRRK2	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign
Select item 1938	NM_198578.4(LRRK2):c.4321C>T (p.Arg1441Cys)	LRRK2 (R1441C)	Single nucleotide variant (missense variant)	not provided +1 more	GPathogenic
Select item 39191	NM_198578.4(LRRK2):c.4541G>A (p.Arg1514Gln)	LRRK2 (R1514Q)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8 +1 more	GBenign/Likely benign
Select item 39193	NM_198578.4(LRRK2):c.4624C>T (p.Pro1542Ser)	LRRK2 (P1542S)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8 +1 more	GBenign/Likely benign
Select item 39201	NM_198578.4(LRRK2):c.4939T>A (p.Ser1647Thr)	LRRK2 (S1647T)	Single nucleotide variant (missense variant)	not provided +1 more	GBenign
Select item 39207	NM_198578.4(LRRK2):c.5183G>T (p.Arg1728Leu)	LRRK2 (R1728L)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 1213043	NM_198578.4(LRRK2):c.5509+20A>C	LRRK2	Single nucleotide variant (intron variant)	not provided +1 more	GBenign/Likely benign
Select item 308639	NM_198578.4(LRRK2):c.5510-9A>G	LRRK2	Single nucleotide variant (intron variant)	not provided +3 more	GBenign/Likely benign
Select item 39216	NM_198578.4(LRRK2):c.5822G>A (p.Arg1941His)	LRRK2 (R1941H)	Single nucleotide variant (missense variant)	not provided +2 more	GUncertain significance
Select item 465216	NM_198578.4(LRRK2):c.5870G>T (p.Arg1957Leu)	LRRK2 (R1957L)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 703949	NM_198578.4(LRRK2):c.5931C>T (p.His1977=)	LRRK2	Single nucleotide variant (synonymous variant)	Autosomal dominant Parkinson disease 8 +1 more	GLikely benign
Select item 1940	NM_198578.4(LRRK2):c.6055G>A (p.Gly2019Ser)	LRRK2 (G2019S)	Single nucleotide variant (missense variant)	Parkinson disease, late-onset +5 more	GPathogenic/Likely pathogenic; risk factor
Select item 39220	NM_198578.4(LRRK2):c.6187_6191del (p.Leu2062_Leu2063insTer)	LRRK2	Deletion (nonsense)	Autosomal dominant Parkinson disease 8 +1 more	GUncertain significance
Select item 1345066	NM_198578.4(LRRK2):c.6220G>A (p.Val2074Ile)	LRRK2 (V2074I)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 39221	NM_198578.4(LRRK2):c.6241A>G (p.Asn2081Asp)	LRRK2 (N2081D)	Single nucleotide variant (missense variant)	not provided +1 more	GBenign/Likely benign
Select item 39222	NM_198578.4(LRRK2):c.6324G>A (p.Glu2108=)	LRRK2	Single nucleotide variant (synonymous variant)	Autosomal dominant Parkinson disease 8 +1 more	GBenign
Select item 39229	NM_198578.4(LRRK2):c.6566A>G (p.Tyr2189Cys)	LRRK2 (Y2189C)	Single nucleotide variant (missense variant)	not provided +1 more	GConflicting classifications of pathogenicity
Select item 1174992	NM_198578.4(LRRK2):c.6844-8dup	LRRK2	Duplication (intron variant)	Autosomal dominant Parkinson disease 8 +1 more	GBenign
Select item 308645	NM_198578.4(LRRK2):c.6844-14_6844-13insA	LRRK2	Insertion (intron variant)	not provided +1 more	GBenign/Likely benign
Select item 1420340	NM_198578.4(LRRK2):c.6928A>G (p.Thr2310Ala)	LRRK2 (T2310A)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8 +1 more	GConflicting classifications of pathogenicity
Select item 1475709	NM_198578.4(LRRK2):c.7146A>C (p.Lys2382Asn)	LRRK2 (K2382N)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8 +1 more	GUncertain significance
Select item 39234	NM_198578.4(LRRK2):c.7155A>G (p.Gly2385=)	LRRK2	Single nucleotide variant (synonymous variant)	not provided +1 more	GBenign/Likely benign
Select item 39237	NM_198578.4(LRRK2):c.7186_7187dup (p.Val2396_Met2397insTer)	LRRK2	Duplication (frameshift variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 1376743	NM_198578.4(LRRK2):c.7324C>T (p.Arg2442Cys)	LRRK2 (R2442C)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 1482826	NM_198578.4(LRRK2):c.7382C>T (p.Ala2461Val)	LRRK2 (A2461V)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 695315	NM_198578.4(LRRK2):c.7429C>T (p.Arg2477Trp)	LRRK2 (R2477W)	Single nucleotide variant (missense variant)	not provided +1 more	GBenign/Likely benign
Select item 1044075	NM_198578.4(LRRK2):c.7430G>A (p.Arg2477Gln)	LRRK2 (R2477Q)	Single nucleotide variant (missense variant)	Autosomal dominant Parkinson disease 8	GUncertain significance
Select item 1626315	NM_198578.4(LRRK2):c.7462+15G>C	LRRK2	Single nucleotide variant (intron variant)	Autosomal dominant Parkinson disease 8 +1 more	GBenign/Likely benign

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Items: 63