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Items: 100

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
GBE1
(R565W)
Single nucleotide variant
(missense variant)
not specified
+6 more
GConflicting classifications of pathogenicity
DOK7
(Q10fs)
Deletion
(frameshift variant)
Inborn genetic diseases
+3 more
GPathogenic/Likely pathogenic
DOK7
Deletion
(intron variant)
Fetal akinesia deformation sequence 1
+3 more
GPathogenic/Likely pathogenic
DOK7
(A99V)
Single nucleotide variant
(missense variant +1 more)
not specified
+3 more
GConflicting classifications of pathogenicity
DOK7
Single nucleotide variant
(splice donor variant +1 more)
DOK7-related disorder
+5 more
GPathogenic
DOK7
Single nucleotide variant
(splice acceptor variant +1 more)
Fetal akinesia deformation sequence 3
+2 more
GLikely pathogenic
DOK7
(G127S)
Single nucleotide variant
(missense variant +1 more)
Congenital myasthenic syndrome
+3 more
GConflicting classifications of pathogenicity
DOK7
Single nucleotide variant
(synonymous variant +1 more)
Congenital myasthenic syndrome 10
+4 more
GLikely pathogenic
DOK7
(V139L)
Single nucleotide variant
(missense variant +1 more)
Fetal akinesia deformation sequence 3
+2 more
GLikely pathogenic
DOK7
(P146L)
Single nucleotide variant
(missense variant +1 more)
Fetal akinesia deformation sequence 3
+2 more
GPathogenic/Likely pathogenic
DOK7
(Y160*)
Single nucleotide variant
(nonsense +1 more)
Fetal akinesia deformation sequence 3
+3 more
GPathogenic
DOK7
(G161R)
Single nucleotide variant
(missense variant +1 more)
Congenital myasthenic syndrome 10
+4 more
GConflicting classifications of pathogenicity
DOK7
(G166R)
Single nucleotide variant
(missense variant +1 more)
Fetal akinesia deformation sequence 3
+3 more
GConflicting classifications of pathogenicity
DOK7
Single nucleotide variant
(synonymous variant +1 more)
Congenital myasthenic syndrome 10
+4 more
GPathogenic/Likely pathogenic
DOK7
(G172R)
Single nucleotide variant
(missense variant +1 more)
not provided
+4 more
GPathogenic/Likely pathogenic
DOK7
(I199fs +2 more)
Deletion
(frameshift variant +1 more)
Fetal akinesia deformation sequence 3
+3 more
GPathogenic/Likely pathogenic
DOK7
(R201* +2 more)
Single nucleotide variant
(missense variant +2 more)
Fetal akinesia deformation sequence 3
+3 more
GPathogenic
DOK7
(P209T +2 more)
Single nucleotide variant
(missense variant +1 more)
Congenital myasthenic syndrome 10
+1 more
GUncertain significance
DOK7, LOC129992118
(H106fs +2 more)
Microsatellite
(frameshift variant +1 more)
Fetal akinesia deformation sequence 3
+2 more
GPathogenic/Likely pathogenic
DOK7, LOC129992118
(A251E +2 more)
Single nucleotide variant
(nonsense +2 more)
Congenital myasthenic syndrome 10
+2 more
GConflicting classifications of pathogenicity
DOK7
Deletion
(splice acceptor variant)
Fetal akinesia deformation sequence 3
+2 more
GConflicting classifications of pathogenicity
DOK7
(S127G +1 more)
Single nucleotide variant
(3 prime UTR variant +2 more)
Fetal akinesia deformation sequence 1
GUncertain significance
DOK7
(A277T +1 more)
Single nucleotide variant
(3 prime UTR variant +2 more)
Fetal akinesia deformation sequence 1
+1 more
GUncertain significance
DOK7
(K320fs +2 more)
Duplication
(3 prime UTR variant +1 more)
Fetal akinesia deformation sequence 1
+3 more
GPathogenic/Likely pathogenic
DOK7
(S194fs +2 more)
Duplication
(3 prime UTR variant +1 more)
Fetal akinesia deformation sequence 3
+2 more
GPathogenic
DOK7
(A234fs +2 more)
Duplication
(3 prime UTR variant +1 more)
Fetal akinesia deformation sequence 3
+7 more
GPathogenic
DOK7
(A70fs +2 more)
Duplication
(3 prime UTR variant +1 more)
Fetal akinesia deformation sequence 3
+3 more
GPathogenic
DOK7
(E238fs +2 more)
Duplication
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 10
+3 more
GPathogenic
DOK7
(E238fs +2 more)
Deletion
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome
+4 more
GPathogenic
DOK7
(V249D +2 more)
Single nucleotide variant
(3 prime UTR variant +1 more)
Fetal akinesia deformation sequence 1
GUncertain significance
DOK7
(C102* +2 more)
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 10
+2 more
GPathogenic
DOK7
(D107fs +2 more)
Microsatellite
(3 prime UTR variant +1 more)
Fetal akinesia deformation sequence 3
+2 more
GPathogenic/Likely pathogenic
DOK7
(S112fs +2 more)
Duplication
(frameshift variant +1 more)
Congenital myasthenic syndrome
+5 more
GPathogenic/Likely pathogenic
DOK7
(S112fs +2 more)
Deletion
(3 prime UTR variant +1 more)
not provided
+3 more
GPathogenic/Likely pathogenic
DOK7
(Q113* +2 more)
Single nucleotide variant
(3 prime UTR variant +1 more)
Fetal akinesia deformation sequence 3
+2 more
GPathogenic/Likely pathogenic
DOK7
(D123fs +2 more)
Deletion
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 10
+3 more
GPathogenic
DOK7
(C132fs +2 more)
Deletion
(3 prime UTR variant +1 more)
Fetal akinesia deformation sequence 3
+2 more
GPathogenic
DOK7
(C298fs +2 more)
Deletion
(3 prime UTR variant +1 more)
Fetal akinesia deformation sequence 3
+2 more
GPathogenic/Likely pathogenic
DOK7
(G448fs +2 more)
Microsatellite
(3 prime UTR variant +1 more)
Fetal akinesia deformation sequence 1
+3 more
GPathogenic
DOK7
(L137fs +2 more)
Microsatellite
(3 prime UTR variant +1 more)
Fetal akinesia deformation sequence 3
+2 more
GPathogenic/Likely pathogenic
DOK7
(Q150fs +2 more)
Duplication
(3 prime UTR variant +1 more)
not provided
+3 more
GPathogenic/Likely pathogenic
DOK7
(Q150fs +2 more)
Deletion
(3 prime UTR variant +1 more)
Fetal akinesia deformation sequence 3
+2 more
GPathogenic
DOK7
(A458D +2 more)
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 10
+3 more
GUncertain significance
DOK7
(Q316* +2 more)
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 10
+2 more
GPathogenic
DOK7
(W475C +2 more)
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 10
+2 more
GUncertain significance
DOK7
(P176fs +2 more)
Deletion
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 10
+3 more
GConflicting classifications of pathogenicity
DOK7
(G352fs +2 more)
Duplication
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 10
+1 more
GPathogenic/Likely pathogenic
MUSK
Single nucleotide variant
(splice donor variant)
Congenital myasthenic syndrome 9
+3 more
GPathogenic
MUSK
Single nucleotide variant
(intron variant)
Fetal akinesia deformation sequence 1
+1 more
GConflicting classifications of pathogenicity
MUSK
(R162S)
Single nucleotide variant
(missense variant)
not provided
+2 more
GConflicting classifications of pathogenicity
MUSK
(P138L +3 more)
Single nucleotide variant
(missense variant)
Fetal akinesia deformation sequence 1
GUncertain significance
MUSK
(A165P +3 more)
Single nucleotide variant
(missense variant)
Fetal akinesia deformation sequence 1
+1 more
GUncertain significance
MUSK
(I764T +3 more)
Single nucleotide variant
(missense variant)
Congenital myasthenic syndrome 9
+2 more
GConflicting classifications of pathogenicity
MUSK
(V790M +3 more)
Single nucleotide variant
(missense variant)
not provided
+3 more
GPathogenic/Likely pathogenic
MUSK
(Y798C +3 more)
Single nucleotide variant
(missense variant)
Fetal akinesia deformation sequence 1
+2 more
GConflicting classifications of pathogenicity
MUSK
(L401P +3 more)
Single nucleotide variant
(missense variant)
Fetal akinesia deformation sequence 1
GUncertain significance
MUSK
(R750H +3 more)
Single nucleotide variant
(missense variant)
Fetal akinesia deformation sequence 1
+1 more
GUncertain significance
MUSK
(R438C +3 more)
Single nucleotide variant
(missense variant)
Congenital myasthenic syndrome 9
+2 more
GUncertain significance
RAPSN
(K314del +1 more)
Microsatellite
(inframe_deletion)
Fetal akinesia deformation sequence 1
+4 more
GPathogenic/Likely pathogenic
RAPSN
(E285fs +1 more)
Deletion
(frameshift variant)
Fetal akinesia deformation sequence 2
+3 more
GConflicting classifications of pathogenicity
RAPSN
(E333* +1 more)
Single nucleotide variant
(nonsense)
Fetal akinesia deformation sequence 2
+3 more
GPathogenic
RAPSN
Deletion
(nonsense)
Fetal akinesia deformation sequence 2
+2 more
GPathogenic
RAPSN
Indel
(intron variant +1 more)
Fetal akinesia deformation sequence 2
+3 more
GPathogenic/Likely pathogenic
RAPSN
Single nucleotide variant
(intron variant +1 more)
Fetal akinesia deformation sequence 2
+2 more
GLikely pathogenic
RAPSN
(G291D)
Single nucleotide variant
(missense variant +1 more)
Congenital myasthenic syndrome 11
+3 more
GConflicting classifications of pathogenicity
RAPSN
(L283P)
Single nucleotide variant
(missense variant +1 more)
Global developmental delay
+5 more
GConflicting classifications of pathogenicity
RAPSN
(A246V)
Single nucleotide variant
(missense variant)
Fetal akinesia deformation sequence 2
+3 more
GPathogenic/Likely pathogenic
RAPSN
(Q245*)
Single nucleotide variant
(nonsense)
Fetal akinesia deformation sequence 2
+2 more
GPathogenic/Likely pathogenic
RAPSN
(R242W)
Single nucleotide variant
(missense variant)
Fetal akinesia deformation sequence 2
+2 more
GConflicting classifications of pathogenicity
RAPSN
(Q238*)
Single nucleotide variant
(nonsense)
Fetal akinesia deformation sequence 1
+2 more
GPathogenic
RAPSN
(W200*)
Single nucleotide variant
(nonsense)
Fetal akinesia deformation sequence 2
+2 more
GPathogenic/Likely pathogenic
RAPSN
(F185fs)
Duplication
(frameshift variant)
Fetal akinesia deformation sequence 1
+3 more
GPathogenic/Likely pathogenic
RAPSN
Single nucleotide variant
(splice donor variant)
Congenital myasthenic syndrome 11
+2 more
GPathogenic/Likely pathogenic
RAPSN
(V165M)
Single nucleotide variant
(missense variant)
not provided
+4 more
GPathogenic/Likely pathogenic
RAPSN
(R164C)
Single nucleotide variant
(missense variant)
Congenital myasthenic syndrome 11
+3 more
GPathogenic/Likely pathogenic
RAPSN
(E162K)
Single nucleotide variant
(missense variant)
Fetal akinesia deformation sequence 2
+2 more
GPathogenic
RAPSN
(A153T)
Single nucleotide variant
(missense variant)
Congenital myasthenic syndrome 11
+3 more
GConflicting classifications of pathogenicity
RAPSN
(E147K)
Single nucleotide variant
(missense variant)
RAPSN-related disorder
+4 more
GPathogenic/Likely pathogenic
RAPSN
(A142D)
Single nucleotide variant
(missense variant)
Fetal akinesia deformation sequence 1
+4 more
GConflicting classifications of pathogenicity
RAPSN
(Q140*)
Single nucleotide variant
(nonsense)
Fetal akinesia deformation sequence 2
+2 more
GPathogenic/Likely pathogenic
RAPSN
(V138I)
Single nucleotide variant
(missense variant)
Congenital myasthenic syndrome 11
+3 more
GConflicting classifications of pathogenicity
RAPSN
(Q124*)
Single nucleotide variant
(nonsense)
Congenital myasthenic syndrome
+4 more
GPathogenic/Likely pathogenic
RAPSN
(H100fs)
Deletion
(frameshift variant)
Fetal akinesia deformation sequence 2
+2 more
GPathogenic/Likely pathogenic
RAPSN
(C97fs)
Deletion
(frameshift variant)
Fetal akinesia deformation sequence 2
+2 more
GPathogenic/Likely pathogenic
RAPSN
(E94K)
Single nucleotide variant
(missense variant)
not specified
+5 more
GConflicting classifications of pathogenicity
RAPSN
(R91L)
Single nucleotide variant
(missense variant)
Fetal akinesia deformation sequence 1
+4 more
GConflicting classifications of pathogenicity
RAPSN
(N88K)
Single nucleotide variant
(missense variant)
Myopathy
+7 more
GPathogenic/Likely pathogenic
RAPSN
(I70fs)
Deletion
(frameshift variant)
Fetal akinesia deformation sequence 2
+2 more
GPathogenic/Likely pathogenic
RAPSN
Deletion
(splice acceptor variant)
Fetal akinesia deformation sequence 2
+2 more
GLikely pathogenic
RAPSN
Single nucleotide variant
(splice donor variant)
Fetal akinesia deformation sequence 2
+3 more
GPathogenic
RAPSN
(V45M)
Single nucleotide variant
(missense variant)
Fetal akinesia deformation sequence 2
+3 more
GPathogenic/Likely pathogenic
RAPSN
(Q21*)
Single nucleotide variant
(nonsense)
Fetal akinesia deformation sequence 1
+2 more
GPathogenic/Likely pathogenic
RAPSN
(L16fs)
Duplication
(frameshift variant)
Fetal akinesia deformation sequence 2
+2 more
GPathogenic
RAPSN
(L14P)
Single nucleotide variant
(missense variant)
not provided
+3 more
GPathogenic/Likely pathogenic
RAPSN
(D4fs)
Duplication
(frameshift variant)
Fetal akinesia deformation sequence 2
+2 more
GPathogenic/Likely pathogenic
RAPSN
Single nucleotide variant
Fetal akinesia deformation sequence 2
+3 more
GPathogenic/Likely pathogenic
RAPSN
Single nucleotide variant
Fetal akinesia deformation sequence 2
+3 more
GPathogenic/Likely pathogenic
PIEZO2
(R2686H +1 more)
Single nucleotide variant
(missense variant)
Fetal akinesia deformation sequence 1
+6 more
GPathogenic
PIEZO2
(Y304C)
Single nucleotide variant
(missense variant)
Arthrogryposis, distal, with impaired proprioception and touch
+2 more
GConflicting classifications of pathogenicity
SETBP1
(I871T)
Single nucleotide variant
(missense variant)
Fetal akinesia deformation sequence 1
+4 more
GConflicting classifications of pathogenicity
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