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Items: 19

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
LOC130002223, TGFBR1
Single nucleotide variant
(5 prime UTR variant)
Loeys-Dietz syndrome 1
+4 more
GConflicting classifications of pathogenicity
TGFBR1
(L14P)
Single nucleotide variant
(missense variant)
Ehlers-Danlos syndrome
+3 more
GUncertain significance
TGFBR1
Microsatellite
(inframe_insertion)
Loeys-Dietz syndrome 1
+2 more
GUncertain significance
TGFBR1
Microsatellite
(inframe_deletion)
Familial thoracic aortic aneurysm and aortic dissection
+2 more
GUncertain significance
TGFBR1
(N45S)
Single nucleotide variant
(missense variant)
Multiple self-healing squamous epithelioma
+6 more
GUncertain significance
TGFBR1
(H67Y)
Single nucleotide variant
(missense variant)
not provided
+5 more
GConflicting classifications of pathogenicity
TGFBR1
(R151C +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+4 more
GUncertain significance
TGFBR1
Single nucleotide variant
(synonymous variant +1 more)
Familial thoracic aortic aneurysm and aortic dissection
+3 more
GLikely benign
TGFBR1
(I205V +2 more)
Single nucleotide variant
(missense variant)
Loeys-Dietz syndrome 1
+4 more
GUncertain significance
TGFBR1
(Y282H +2 more)
Single nucleotide variant
(missense variant)
Loeys-Dietz syndrome 1
+5 more
GConflicting classifications of pathogenicity
TGFBR1
(V297I +2 more)
Single nucleotide variant
(missense variant)
Loeys-Dietz syndrome 1
+2 more
GUncertain significance
TGFBR1
(T309M +2 more)
Single nucleotide variant
(missense variant)
Familial thoracic aortic aneurysm and aortic dissection
+3 more
GUncertain significance
TGFBR1
(A310V +2 more)
Single nucleotide variant
(missense variant)
Familial thoracic aortic aneurysm and aortic dissection
+4 more
GUncertain significance
TGFBR1
(E242D +2 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GUncertain significance
TGFBR1
(C347S +2 more)
Single nucleotide variant
(missense variant)
Loeys-Dietz syndrome
+4 more
GUncertain significance
TGFBR1
Single nucleotide variant
(synonymous variant)
not provided
+3 more
GUncertain significance
TGFBR1
(T364S +2 more)
Single nucleotide variant
(missense variant)
Loeys-Dietz syndrome
+4 more
GConflicting classifications of pathogenicity
TGFBR1
(N401S +2 more)
Single nucleotide variant
(missense variant)
Ehlers-Danlos syndrome
+6 more
GConflicting classifications of pathogenicity
TGFBR1
(R487W +2 more)
Single nucleotide variant
(missense variant)
not provided
+4 more
GPathogenic/Likely pathogenic
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