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Items: 27

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
MTOR
(E1799K)
Single nucleotide variant
(missense variant)
CEBALID syndrome
+5 more
GPathogenic
AGO1
(F180del +1 more)
Microsatellite
(inframe_deletion)
Neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizures
+8 more
GConflicting classifications of pathogenicity
ST3GAL3
(R173C +14 more)
Single nucleotide variant
(missense variant +3 more)
Intellectual disability, autosomal recessive 12
GLikely pathogenic
METTL5
(K191fs)
Deletion
(frameshift variant)
Intellectual disability, severe
+1 more
GPathogenic/Likely pathogenic
METTL5
(R115fs)
Deletion
(frameshift variant)
Intellectual disability, severe
+1 more
GPathogenic
HDAC4
(T244K)
Single nucleotide variant
(missense variant)
HDAC4-related disorder
+1 more
GPathogenic/Likely pathogenic
KCNN2
(Y372* +1 more)
Single nucleotide variant
(nonsense)
Motor tics
+3 more
GPathogenic
TMEM67
(C615R +1 more)
Single nucleotide variant
(missense variant +1 more)
Pancreatitis
+26 more
GPathogenic/Likely pathogenic
CAMK2G
(R292P +5 more)
Single nucleotide variant
(missense variant +1 more)
Global developmental delay
+4 more
GPathogenic/Likely pathogenic
COPB1
(F551V)
Single nucleotide variant
(missense variant)
Baralle-Macken syndrome
GPathogenic
COPB1
Single nucleotide variant
(splice donor variant)
Baralle-Macken syndrome
+3 more
GPathogenic/Likely pathogenic
CHKA
(F201L +5 more)
Single nucleotide variant
(missense variant +1 more)
Neurodevelopmental disorder with microcephaly, movement abnormalities, and seizures
+3 more
GLikely pathogenic
CHKA
(P176S +4 more)
Single nucleotide variant
(missense variant +2 more)
Microcephaly
+2 more
GLikely pathogenic
CHKA
(R141W +1 more)
Single nucleotide variant
(missense variant +1 more)
Microcephaly
+2 more
GLikely pathogenic
CHKA
(C6fs)
Duplication
(frameshift variant +2 more)
Neurodevelopmental disorder with microcephaly, movement abnormalities, and seizures
+3 more
GLikely pathogenic
CHKA
(M1T)
Single nucleotide variant
(missense variant +3 more)
Microcephaly
+2 more
GUncertain significance
PPFIBP1
(R135*)
Single nucleotide variant
(5 prime UTR variant +1 more)
Cerebral calcification
+3 more
GPathogenic
PPFIBP1
(E320fs +3 more)
Microsatellite
(frameshift variant)
Intellectual disability, severe
+3 more
GPathogenic
PPFIBP1
(Q354* +3 more)
Single nucleotide variant
(nonsense)
Cerebral calcification
+3 more
GPathogenic
PPFIBP1
(R658* +3 more)
Single nucleotide variant
(nonsense)
Cerebral calcification
+3 more
GPathogenic
PPFIBP1
(Y738fs +3 more)
Deletion
(frameshift variant)
Cerebral calcification
+3 more
GPathogenic
NAGLU
(S169fs)
Deletion
(frameshift variant)
Hypertrichosis
+10 more
GPathogenic
TMEM147
Single nucleotide variant
(intron variant)
not provided
+5 more
GPathogenic/Likely pathogenic
NOVA2
(V261fs)
Deletion
(frameshift variant)
Intellectual disability, severe
GPathogenic
ASXL1
(R404* +1 more)
Single nucleotide variant
(nonsense)
not provided
+14 more
GPathogenic
CSTB
(R68*)
Single nucleotide variant
(nonsense)
not provided
+10 more
GPathogenic
ATRX
(R2348* +1 more)
Single nucleotide variant
(nonsense)
not provided
+8 more
GPathogenic
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