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Items: 1 to 100 of 6273

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
SDHB
Single nucleotide variant
(synonymous variant)
Gastrointestinal stromal tumor
+8 more
GBenign
FH
Single nucleotide variant
(synonymous variant)
Hereditary cancer-predisposing syndrome
+4 more
GBenign
EPCAM
(M115T)
Single nucleotide variant
(missense variant)
Lynch syndrome 1
+5 more
GBenign
ATR
(R2407H +1 more)
Single nucleotide variant
(missense variant)
Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome
+3 more
GUncertain significance
ATR
(K297N)
Single nucleotide variant
(missense variant)
Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome
+4 more
GBenign/Likely benign
SDHA
Single nucleotide variant
(intron variant)
not provided
+8 more
GBenign
SDHA
Single nucleotide variant
(synonymous variant)
Leigh syndrome
+8 more
GBenign
PMS2
(P470S +7 more)
Single nucleotide variant
(missense variant +1 more)
Lynch syndrome
GBenign
PMS2
Single nucleotide variant
(synonymous variant +2 more)
Lynch syndrome
GBenign
PMS2
Single nucleotide variant
(intron variant)
Lynch syndrome
GBenign
EGFR, EGFR-AS1
Single nucleotide variant
(non-coding transcript variant +1 more)
Hereditary cancer-predisposing syndrome
+6 more
GBenign
MET
Single nucleotide variant
(synonymous variant +1 more)
Autosomal recessive nonsyndromic hearing loss 97
+5 more
GBenign
MET
Single nucleotide variant
(synonymous variant)
Renal cell carcinoma
+5 more
GBenign
MET
Single nucleotide variant
(synonymous variant)
Renal cell carcinoma
+5 more
GBenign
MET
Single nucleotide variant
(synonymous variant)
not specified
+5 more
GBenign
NBN
(Y749F +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
(N747S +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+2 more
GUncertain significance
NBN
(Y746* +1 more)
Single nucleotide variant
(nonsense)
Aplastic anemia
+3 more
GConflicting classifications of pathogenicity
NBN
Single nucleotide variant
(intron variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
NBN
(L661fs +1 more)
Deletion
(frameshift variant)
Microcephaly, normal intelligence and immunodeficiency
+1 more
GUncertain significance
NBN
(D742E +1 more)
Single nucleotide variant
(missense variant)
Aplastic anemia
+2 more
GUncertain significance
NBN
(D742E +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
NBN
(D742Y +1 more)
Single nucleotide variant
(missense variant)
not specified
+2 more
GUncertain significance
NBN
(L739V +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+4 more
GUncertain significance
NBN
(S738F +1 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GUncertain significance
NBN
(E737D +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
(E737V +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+2 more
GUncertain significance
NBN
(E654Q +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+1 more
GUncertain significance
NBN
(E736* +1 more)
Single nucleotide variant
(nonsense)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
Single nucleotide variant
(synonymous variant)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GBenign/Likely benign
NBN
(A734V +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
(H733R +1 more)
Single nucleotide variant
(missense variant)
not provided
+3 more
GUncertain significance
NBN
(H733D +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+1 more
GUncertain significance
NBN
(N731Y +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
NBN
Single nucleotide variant
(splice donor variant)
Hereditary cancer-predisposing syndrome
+2 more
GLikely pathogenic
NBN
(E644K +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
(Q643R +1 more)
Single nucleotide variant
(missense variant)
not provided
+3 more
GUncertain significance
NBN
(Q725P +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
(W722S +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+2 more
GUncertain significance
NBN
(W722G +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
(E721* +1 more)
Single nucleotide variant
(nonsense)
not provided
+3 more
GPathogenic/Likely pathogenic
NBN
(E720K +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
Duplication
(inframe_insertion)
Microcephaly, normal intelligence and immunodeficiency
+2 more
GUncertain significance
NBN
(T717I +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+1 more
GUncertain significance
NBN
(T717S +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+5 more
GUncertain significance
NBN
(R714Q +1 more)
Single nucleotide variant
(missense variant)
Aplastic anemia
+3 more
GUncertain significance
NBN
(R714G +1 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GConflicting classifications of pathogenicity
NBN
(R714* +1 more)
Single nucleotide variant
(nonsense)
Aplastic anemia
+4 more
GPathogenic/Likely pathogenic
NBN
(A713G +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+1 more
GUncertain significance
NBN
(H630Y +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
NBN
(H712N +1 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GUncertain significance
NBN
(H711Y +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
NBN
(A710V +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+2 more
GUncertain significance
NBN
Deletion
(inframe_deletion)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
(A710P +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GConflicting classifications of pathogenicity
NBN
(S706* +1 more)
Single nucleotide variant
(nonsense)
Hereditary cancer-predisposing syndrome
+4 more
GPathogenic/Likely pathogenic
NBN
(P700T +1 more)
Single nucleotide variant
(missense variant)
not specified
+3 more
GUncertain significance
NBN
(A696V +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+1 more
GUncertain significance
NBN
(A696S +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
(G695E +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
(P694R +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
NBN
(T692I +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
NBN
(V609F +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
(V691I +1 more)
Single nucleotide variant
(missense variant)
Aplastic anemia
+2 more
GUncertain significance
NBN
Single nucleotide variant
(intron variant)
Hereditary cancer-predisposing syndrome
+1 more
GConflicting classifications of pathogenicity
NBN
Single nucleotide variant
(intron variant)
not provided
+3 more
GUncertain significance
NBN
Single nucleotide variant
(intron variant)
not provided
+3 more
GConflicting classifications of pathogenicity
NBN
Single nucleotide variant
(splice donor variant)
Hereditary cancer-predisposing syndrome
+1 more
GLikely pathogenic
NBN
(K690Q +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
NBN
(K687T +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+2 more
GUncertain significance
NBN
(F603S +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GUncertain significance
NBN
(N684S +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
(G598V +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
(G680S +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
NBN
(Y679C +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+2 more
GUncertain significance
NBN
(D677N +1 more)
Single nucleotide variant
(missense variant)
not specified
+4 more
GConflicting classifications of pathogenicity
NBN
(N676S +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
Single nucleotide variant
(synonymous variant)
Microcephaly, normal intelligence and immunodeficiency
+1 more
GConflicting classifications of pathogenicity
NBN
Single nucleotide variant
(synonymous variant)
Acute lymphoid leukemia
+5 more
GBenign
NBN
(P672L +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+2 more
GConflicting classifications of pathogenicity
NBN
(N671S +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
NBN
(T668I +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+1 more
GUncertain significance
NBN
(T668A +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+1 more
GUncertain significance
NBN
(S667P +1 more)
Single nucleotide variant
(missense variant)
Aplastic anemia
+5 more
GConflicting classifications of pathogenicity
NBN
(K665E +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GConflicting classifications of pathogenicity
NBN
Single nucleotide variant
(synonymous variant)
Microcephaly, normal intelligence and immunodeficiency
+2 more
GConflicting classifications of pathogenicity
NBN
(R660K +1 more)
Single nucleotide variant
(missense variant)
not provided
+3 more
GUncertain significance
NBN
(R660T +1 more)
Single nucleotide variant
(missense variant)
NBN-related disorder
+5 more
GConflicting classifications of pathogenicity
NBN
(E576fs)
Deletion
(frameshift variant)
Aplastic anemia
+3 more
GPathogenic/Likely pathogenic
NBN
(E658G +1 more)
Single nucleotide variant
(missense variant)
Aplastic anemia
+3 more
GUncertain significance
NBN
(M649I +1 more)
Single nucleotide variant
(missense variant)
not specified
+2 more
GUncertain significance
NBN
(M649T +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
NBN
(S647R +1 more)
Single nucleotide variant
(missense variant)
Aplastic anemia
+3 more
GUncertain significance
NBN
(D645Y +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
NBN
(D645N +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+2 more
GUncertain significance
NBN
(Q644K +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
NBN
(K642R +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
NBN
(N640S +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
NBN
Single nucleotide variant
(intron variant)
Hereditary cancer-predisposing syndrome
+2 more
GConflicting classifications of pathogenicity
LOC126860438, NBN
Single nucleotide variant
(intron variant)
not provided
+3 more
GConflicting classifications of pathogenicity
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