"deCODE genetics, Amgen"[submitter] AND "MSH6"[gene] - ClinVar

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 576557	NM_000179.3(MSH6):c.394C>T (p.Gln132Ter)	MSH6 (Q132*)	Single nucleotide variant (nonsense +2 more)	Hereditary nonpolyposis colorectal neoplasms +1 more	GPathogenic
Select item 2574105	NM_000179.3(MSH6):c.457+1G>A	MSH6 (G153D)	Single nucleotide variant (missense variant +2 more)	Lynch syndrome 5	GLikely pathogenic
Select item 1763360	NM_000179.3(MSH6):c.843_844insAC (p.Val282fs)	MSH6 (V152fs +1 more)	Insertion (frameshift variant +1 more)	Lynch syndrome 5 +1 more	GPathogenic
Select item 89220	NM_000179.3(MSH6):c.1754T>C (p.Leu585Pro)	MSH6 (L585P +2 more)	Single nucleotide variant (missense variant)	not provided +5 more	GPathogenic/Likely pathogenic
Select item 89330	NM_000179.3(MSH6):c.3013C>T (p.Arg1005Ter)	MSH6 (R1005* +2 more)	Single nucleotide variant (nonsense)	Lynch syndrome	GPathogenic
Select item 89364	NM_000179.3(MSH6):c.3261dup (p.Phe1088fs)	MSH6 (F1088fs +2 more)	Duplication (frameshift variant)	Lynch syndrome	GPathogenic

ClinVar