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Items: 32

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
SMPD1
(G34D)
Single nucleotide variant
(missense variant +2 more)
not provided
GUncertain significance
SMPD1
(L35V)
Single nucleotide variant
(missense variant +2 more)
not provided
+3 more
GConflicting classifications of pathogenicity
SMPD1
(D51V)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type B
+3 more
GConflicting classifications of pathogenicity
SMPD1
Single nucleotide variant
(splice donor variant)
not provided
GPathogenic
SMPD1
(V114M +1 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type A
+5 more
GUncertain significance
SMPD1
(C159R +1 more)
Single nucleotide variant
(missense variant +2 more)
Sphingomyelin/cholesterol lipidosis
+3 more
GPathogenic/Likely pathogenic
SMPD1
(P186L +1 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type A
+3 more
GPathogenic
SMPD1
(A198P +1 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type B
+3 more
GConflicting classifications of pathogenicity
SMPD1
(G244* +1 more)
Single nucleotide variant
(nonsense +2 more)
Sphingomyelin/cholesterol lipidosis
+2 more
GPathogenic/Likely pathogenic
SMPD1
(G244R +1 more)
Single nucleotide variant
(missense variant +2 more)
not specified
+4 more
GConflicting classifications of pathogenicity
SMPD1
(G247S +1 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type A
+3 more
GPathogenic/Likely pathogenic
SMPD1
(R291H +1 more)
Single nucleotide variant
(missense variant +2 more)
Inborn genetic diseases
+5 more
GUncertain significance
SMPD1
(F332fs +2 more)
Deletion
(frameshift variant +1 more)
Niemann-Pick disease, type A
+3 more
GPathogenic
SMPD1
(P332R +2 more)
Single nucleotide variant
(missense variant +1 more)
Sphingomyelin/cholesterol lipidosis
+4 more
GConflicting classifications of pathogenicity
SMPD1
(E351* +1 more)
Single nucleotide variant
(nonsense +2 more)
not provided
+3 more
GPathogenic/Likely pathogenic
SMPD1
(R389C +2 more)
Single nucleotide variant
(missense variant +2 more)
not provided
+2 more
GUncertain significance
SMPD1
(R389H +2 more)
Single nucleotide variant
(missense variant +2 more)
not provided
+2 more
GUncertain significance
SMPD1
(R111Q +2 more)
Single nucleotide variant
(missense variant +2 more)
not specified
+3 more
GConflicting classifications of pathogenicity
SMPD1
(H423Y +3 more)
Single nucleotide variant
(missense variant +1 more)
Niemann-Pick disease, type A
+3 more
GPathogenic
SMPD1
(R476W +3 more)
Single nucleotide variant
(missense variant +1 more)
Sphingomyelin/cholesterol lipidosis
+4 more
GPathogenic/Likely pathogenic
SMPD1
(P477L +3 more)
Single nucleotide variant
(missense variant +1 more)
Niemann-Pick disease, type A
+3 more
GPathogenic/Likely pathogenic
SMPD1
Single nucleotide variant
(intron variant)
Niemann-Pick disease, type B
+2 more
GConflicting classifications of pathogenicity
SMPD1
(R498C +3 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type A
+3 more
GPathogenic/Likely pathogenic
APBB1, SMPD1
(R498L +4 more)
Single nucleotide variant
(missense variant +1 more)
Niemann-Pick disease, type A
+4 more
GPathogenic/Likely pathogenic
SMPD1
(S510F +3 more)
Single nucleotide variant
(missense variant +2 more)
not specified
+3 more
GConflicting classifications of pathogenicity
SMPD1
(W535R +3 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type A
+1 more
GLikely pathogenic
SMPD1
(R542* +3 more)
Single nucleotide variant
(nonsense +2 more)
not provided
+4 more
GConflicting classifications of pathogenicity
SMPD1
(H577R +3 more)
Single nucleotide variant
(missense variant +2 more)
not provided
+3 more
GConflicting classifications of pathogenicity
SMPD1
(L292I +3 more)
Single nucleotide variant
(missense variant +2 more)
not provided
GUncertain significance
SMPD1
(R602H +3 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type A
+3 more
GPathogenic/Likely pathogenic
APBB1, SMPD1
(R610del +3 more)
Microsatellite
(inframe_deletion +2 more)
not specified
+3 more
GPathogenic
SMPD1
(R566C +3 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type B
+2 more
GConflicting classifications of pathogenicity
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