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Items: 27

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
NBN
Single nucleotide variant
(splice donor variant)
Hereditary cancer-predisposing syndrome
+2 more
GLikely pathogenic
LOC126860438, NBN
(K627R +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
NBN
(R551fs +1 more)
Duplication
(frameshift variant)
Hereditary cancer-predisposing syndrome
+3 more
GPathogenic
NBN
(K468fs +1 more)
Deletion
(frameshift variant)
Hereditary cancer-predisposing syndrome
+4 more
GPathogenic/Likely pathogenic
NBN
(P413fs +1 more)
Indel
(frameshift variant)
Microcephaly, normal intelligence and immunodeficiency
+4 more
GPathogenic/Likely pathogenic
NBN
(Q494K +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GUncertain significance
NBN
(Q448L +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+4 more
GConflicting classifications of pathogenicity
NBN
(N337fs +1 more)
Deletion
(frameshift variant)
not provided
+3 more
GPathogenic/Likely pathogenic
NBN
(K322* +1 more)
Single nucleotide variant
(nonsense)
not provided
GLikely pathogenic
NBN
(Q391* +1 more)
Single nucleotide variant
(nonsense)
not provided
+2 more
GPathogenic
NBN
(E301del +1 more)
Deletion
(inframe_deletion +1 more)
not provided
GUncertain significance
NBN
(V346M +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+5 more
GConflicting classifications of pathogenicity
NBN
(Q344* +1 more)
Single nucleotide variant
(nonsense)
Microcephaly, normal intelligence and immunodeficiency
+4 more
GPathogenic/Likely pathogenic
NBN
Single nucleotide variant
(splice acceptor variant)
NBN-related disorder
+5 more
GLikely pathogenic
NBN
(V270fs +1 more)
Microsatellite
(frameshift variant)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GPathogenic/Likely pathogenic
NBN
(T253I +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+3 more
GConflicting classifications of pathogenicity
NBN
(K137fs +1 more)
Deletion
(frameshift variant)
Microcephaly
+6 more
GPathogenic
NBN
(R215Q +1 more)
Single nucleotide variant
(missense variant)
not specified
+4 more
GUncertain significance
NBN
Single nucleotide variant
(intron variant)
Microcephaly, normal intelligence and immunodeficiency
+2 more
GUncertain significance
NBN
(I171V +1 more)
Single nucleotide variant
(missense variant)
Hereditary breast ovarian cancer syndrome
+9 more
GConflicting classifications of pathogenicity
NBN
(M152I +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+5 more
GConflicting classifications of pathogenicity
NBN
(Y28*)
Single nucleotide variant
(nonsense)
not provided
GPathogenic
NBN
(F20fs)
Deletion
(frameshift variant)
Aplastic anemia
+3 more
GPathogenic/Likely pathogenic
NBN
(R89* +1 more)
Single nucleotide variant
(nonsense)
Aplastic anemia
+4 more
GPathogenic/Likely pathogenic
NBN
(Q59*)
Single nucleotide variant
(5 prime UTR variant +1 more)
not provided
+4 more
GPathogenic/Likely pathogenic
NBN
(D38V)
Single nucleotide variant
(5 prime UTR variant +1 more)
not provided
+1 more
GUncertain significance
NBN
Single nucleotide variant
(splice donor variant)
Microcephaly, normal intelligence and immunodeficiency
+4 more
GPathogenic/Likely pathogenic
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