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Items: 38

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
CHRNA1
(G473D +1 more)
Single nucleotide variant
(missense variant)
Lethal multiple pterygium syndrome
+1 more
GUncertain significance
CHRNA1
(G441R +1 more)
Single nucleotide variant
(missense variant)
Lethal multiple pterygium syndrome
+2 more
GPathogenic/Likely pathogenic
CHRNA1
(G432R +1 more)
Single nucleotide variant
(missense variant)
Congenital myasthenic syndrome
+3 more
GConflicting classifications of pathogenicity
CHRNA1
(V447I +1 more)
Single nucleotide variant
(missense variant)
Lethal multiple pterygium syndrome
+1 more
GUncertain significance
CHRNA1
(A441V +1 more)
Single nucleotide variant
(missense variant)
Congenital myasthenic syndrome
+3 more
GUncertain significance
CHRNA1
(N439K +1 more)
Single nucleotide variant
(missense variant)
Lethal multiple pterygium syndrome
+2 more
GUncertain significance
CHRNA1
(K407N +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
CHRNA1
(S394R +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
CHRNA1
Single nucleotide variant
(synonymous variant)
not provided
+1 more
GConflicting classifications of pathogenicity
CHRNA1
(M405T +1 more)
Single nucleotide variant
(missense variant)
Lethal multiple pterygium syndrome
+1 more
GConflicting classifications of pathogenicity
CHRNA1
(P377R +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
CHRNA1
(K356T +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+2 more
GConflicting classifications of pathogenicity
CHRNA1
(E355G +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GConflicting classifications of pathogenicity
CHRNA1
(F361V +1 more)
Single nucleotide variant
(missense variant)
Lethal multiple pterygium syndrome
+1 more
GUncertain significance
CHRNA1
(I284L +1 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
CHRNA1
(V281M +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
CHRNA1
Single nucleotide variant
(splice acceptor variant)
not provided
GLikely pathogenic
CHRNA1
(S271F +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GConflicting classifications of pathogenicity
CHRNA1
(N237S +1 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
CHRNA1
(V226I +1 more)
Single nucleotide variant
(missense variant)
Lethal multiple pterygium syndrome
+2 more
GConflicting classifications of pathogenicity
CHRNA1
(G194R +1 more)
Single nucleotide variant
(missense variant)
Lethal multiple pterygium syndrome
+1 more
GUncertain significance
CHRNA1
(V176M +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
CHRNA1
(G173S +1 more)
Single nucleotide variant
(missense variant)
Congenital myopathy
+3 more
GPathogenic/Likely pathogenic
CHRNA1
(I150M +1 more)
Single nucleotide variant
(missense variant)
Lethal multiple pterygium syndrome
+2 more
GUncertain significance
CHRNA1
(P165S +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
CHRNA1
(A121T +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+2 more
GUncertain significance
CHRNA1
(R107H +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
CHRNA1
(R107S +1 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
CHRNA1
(R107C +1 more)
Single nucleotide variant
(missense variant)
Congenital myasthenic syndrome
+3 more
GConflicting classifications of pathogenicity
CHRNA1
(K104E +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
CHRNA1
(G119C +1 more)
Single nucleotide variant
(missense variant)
Lethal multiple pterygium syndrome
+1 more
GConflicting classifications of pathogenicity
CHRNA1
(R86H)
Single nucleotide variant
(missense variant +1 more)
Myasthenic syndrome, congenital, 1B, fast-channel
+2 more
GConflicting classifications of pathogenicity
CHRNA1
(R75H)
Single nucleotide variant
(missense variant)
Congenital myasthenic syndrome
+2 more
GConflicting classifications of pathogenicity
CHRNA1
(Q59H)
Single nucleotide variant
(missense variant)
Lethal multiple pterygium syndrome
+1 more
GUncertain significance
CHRNA1
(V49M)
Single nucleotide variant
(missense variant)
Lethal multiple pterygium syndrome
+1 more
GUncertain significance
CHRNA1
(E22K)
Single nucleotide variant
(missense variant)
not provided
+1 more
GConflicting classifications of pathogenicity
CHRNA1
(V18L)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
CHRNA1
(P5S)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
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