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Items: 53

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
C17orf107, CHRNE
(M312del)
Deletion
(5 prime UTR variant +1 more)
Congenital myasthenic syndrome 4A
+3 more
GPathogenic/Likely pathogenic
C17orf107, CHRNE
(R306M)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+3 more
GConflicting classifications of pathogenicity
C17orf107, CHRNE
(P302S)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
GUncertain significance
C17orf107, CHRNE
(V301M)
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome
+4 more
GConflicting classifications of pathogenicity
C17orf107, CHRNE
(L299P)
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome
+5 more
GUncertain significance
C17orf107, CHRNE
Deletion
(3 prime UTR variant +1 more)
not provided
GUncertain significance
C17orf107, CHRNE
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 4A
+1 more
GConflicting classifications of pathogenicity
C17orf107, CHRNE
(A266V)
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome
+2 more
GConflicting classifications of pathogenicity
C17orf107, CHRNE
(P265fs)
Deletion
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 4A
+1 more
GPathogenic
C17orf107, CHRNE
(R237H)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+5 more
GUncertain significance
C17orf107, CHRNE
(R237L)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+4 more
GConflicting classifications of pathogenicity
C17orf107, CHRNE
(R237C)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+1 more
GUncertain significance
C17orf107, CHRNE
(D229fs)
Deletion
(3 prime UTR variant +1 more)
not provided
+1 more
GPathogenic/Likely pathogenic
C17orf107, CHRNE
(G224D)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+2 more
GConflicting classifications of pathogenicity
CHRNE, C17orf107
(G224S)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+2 more
GUncertain significance
C17orf107, CHRNE
(D223N)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
GUncertain significance
C17orf107, CHRNE
(H217R)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
GUncertain significance
C17orf107, CHRNE
Deletion
(3 prime UTR variant +1 more)
not provided
GLikely pathogenic
C17orf107, CHRNE
(P211L)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+1 more
GConflicting classifications of pathogenicity
C17orf107, CHRNE
(W205fs)
Deletion
(frameshift variant +1 more)
Congenital myasthenic syndrome 4B
+4 more
GPathogenic
C17orf107, CHRNE
(A206V)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
GUncertain significance
C17orf107, CHRNE
(G203A)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
GUncertain significance
CHRNE, C17orf107
(T200A)
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 4A
+1 more
GUncertain significance
C17orf107, CHRNE
(I194T)
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 4B
+6 more
GUncertain significance
C17orf107, CHRNE
(E177fs)
Deletion
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 4A
+3 more
GPathogenic/Likely pathogenic
C17orf107, CHRNE
(T170R)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+1 more
GUncertain significance
C17orf107, CHRNE
(Q169R)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+2 more
GUncertain significance
C17orf107, CHRNE
(Q169L)
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 4C
+5 more
GConflicting classifications of pathogenicity
C17orf107, CHRNE
Duplication
(splice acceptor variant +1 more)
Congenital myasthenic syndrome 4A
+1 more
GConflicting classifications of pathogenicity
C17orf107, CHRNE
(S163W)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+1 more
GConflicting classifications of pathogenicity
C17orf107, CHRNE
(S163L)
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 4A
+2 more
GLikely pathogenic
C17orf107, CHRNE
(C148S)
Single nucleotide variant
(3 prime UTR variant +1 more)
Abnormality of the musculature
+2 more
GPathogenic/Likely pathogenic
C17orf107, CHRNE
(V136M)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+1 more
GUncertain significance
C17orf107, CHRNE
(S135C)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+2 more
GUncertain significance
C17orf107, CHRNE
(F120S)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+1 more
GUncertain significance
C17orf107, CHRNE
(Q119*)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+1 more
GPathogenic/Likely pathogenic
C17orf107, CHRNE
(L104P)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+1 more
GUncertain significance
C17orf107, CHRNE
(P101A)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+1 more
GUncertain significance
C17orf107, CHRNE
(R84*)
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 4A
+1 more
GPathogenic
C17orf107, CHRNE
(D82N)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
GUncertain significance
C17orf107, CHRNE
(L70F)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
GUncertain significance
C17orf107, CHRNE
(L60F)
Single nucleotide variant
(3 prime UTR variant +1 more)
Inborn genetic diseases
+2 more
GUncertain significance
C17orf107, CHRNE
(S52N)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+1 more
GUncertain significance
CHRNE, C17orf107
(E44fs)
Duplication
(frameshift variant +1 more)
Congenital myasthenic syndrome 4A
+6 more
GPathogenic
C17orf107, CHRNE
(R43W)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
GUncertain significance
C17orf107, CHRNE
(R40W)
Single nucleotide variant
(3 prime UTR variant +1 more)
Congenital myasthenic syndrome 4A
+3 more
GUncertain significance
CHRNE, C17orf107
(Y35H)
Single nucleotide variant
(3 prime UTR variant +1 more)
Tip-toe gait
+5 more
GPathogenic/Likely pathogenic
C17orf107, CHRNE
(R26H)
Single nucleotide variant
(3 prime UTR variant +1 more)
Inborn genetic diseases
+2 more
GConflicting classifications of pathogenicity
C17orf107, CHRNE
(L25V)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
GUncertain significance
C17orf107, CHRNE
(V19L)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
GUncertain significance
C17orf107, CHRNE
(G16S)
Single nucleotide variant
(missense variant)
Congenital myasthenic syndrome 4A
+1 more
GUncertain significance
CHRNE, C17orf107
(L11F)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
C17orf107, CHRNE
(L6F)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
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