"Mayo Clinic Laboratories, Mayo Clinic"[submitter] AND "STK11"[gene] - ClinVar

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Items: 24

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 428793	NM_000455.5(STK11):c.159_170del (p.Asp53_Gly56del)	STK11	Deletion (inframe_deletion)	Hereditary cancer-predisposing syndrome +1 more	GConflicting classifications of pathogenicity
Select item 2474945	NM_000455.5(STK11):c.157del (p.Asp53fs)	STK11 (D53fs)	Deletion (frameshift variant +1 more)	not provided +1 more	GPathogenic
Select item 256204	NM_000455.5(STK11):c.374+24G>T	STK11	Single nucleotide variant	not provided +3 more	GBenign
Select item 182906	NM_000455.5(STK11):c.397G>A (p.Val133Met)	STK11 (V133M)	Single nucleotide variant (missense variant)	Hepatoblastoma +4 more	GConflicting classifications of pathogenicity
Select item 141508	NM_000455.5(STK11):c.449T>C (p.Val150Ala)	STK11 (V150A)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +4 more	GConflicting classifications of pathogenicity
Select item 139331	NM_000455.5(STK11):c.464+9G>A	STK11	Single nucleotide variant (intron variant)	not specified +4 more	GBenign/Likely benign
Select item 492741	NM_000455.5(STK11):c.527A>C (p.Asp176Ala)	STK11 (D176A)	Single nucleotide variant (missense variant)	not specified	GUncertain significance
Select item 185384	NM_000455.5(STK11):c.582C>A (p.Asp194Glu)	STK11 (D194E)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +1 more	GLikely pathogenic
Select item 492742	NM_000455.5(STK11):c.710A>G (p.Asp237Gly)	STK11 (D237G)	Single nucleotide variant (missense variant)	not specified	GUncertain significance
Select item 139334	NM_000455.5(STK11):c.734+20G>A	STK11	Single nucleotide variant (intron variant)	Hereditary cancer-predisposing syndrome +3 more	GConflicting classifications of pathogenicity
Select item 141192	NM_000455.5(STK11):c.816C>T (p.Tyr272=)	STK11	Single nucleotide variant (synonymous variant)	not specified +4 more	GBenign
Select item 492743	NM_000455.5(STK11):c.862+26A>C	STK11	Single nucleotide variant (intron variant)	not specified	GLikely benign
Select item 93099	NM_000455.5(STK11):c.920+7G>C	STK11	Single nucleotide variant (intron variant)	Hereditary cancer-predisposing syndrome +3 more	GBenign
Select item 135929	NM_000455.5(STK11):c.945G>A (p.Pro315=)	STK11	Single nucleotide variant (synonymous variant)	not specified +4 more	GBenign/Likely benign
Select item 458074	NM_000455.5(STK11):c.947C>G (p.Ala316Gly)	STK11 (A316G)	Single nucleotide variant (missense variant)	not specified +3 more	GConflicting classifications of pathogenicity
Select item 127710	NM_000455.5(STK11):c.970C>G (p.Pro324Ala)	STK11 (P324A)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +3 more	GConflicting classifications of pathogenicity
Select item 140986	NM_000455.5(STK11):c.1027G>A (p.Asp343Asn)	LOC130062899, STK11 (D343N)	Single nucleotide variant (missense variant)	not specified +3 more	GConflicting classifications of pathogenicity
Select item 7461	NM_000455.5(STK11):c.1062C>G (p.Phe354Leu)	LOC130062899, STK11 (F354L)	Single nucleotide variant (missense variant)	Melanoma, cutaneous malignant, susceptibility to, 1 +7 more	GBenign/Likely benign
Select item 184046	NM_000455.5(STK11):c.1180G>A (p.Gly394Ser)	STK11 (G394S)	Single nucleotide variant (missense variant)	Embryonal rhabdomyosarcoma +7 more	GUncertain significance
Select item 135917	NM_000455.5(STK11):c.1225C>T (p.Arg409Trp)	STK11 (R409W)	Single nucleotide variant (missense variant)	not specified +3 more	GConflicting classifications of pathogenicity
Select item 135918	NM_000455.5(STK11):c.1254C>G (p.Cys418Trp)	STK11 (C418W)	Single nucleotide variant (missense variant)	not specified +3 more	GConflicting classifications of pathogenicity
Select item 141156	NM_000455.5(STK11):c.1283C>G (p.Ser428Trp)	STK11 (S428W)	Single nucleotide variant (missense variant)	Hereditary cancer-predisposing syndrome +3 more	GConflicting classifications of pathogenicity
Select item 216428	NM_000455.5(STK11):c.1286C>G (p.Ala429Gly)	STK11 (A429G)	Single nucleotide variant (missense variant)	not provided +2 more	GConflicting classifications of pathogenicity
Select item 139340	NM_000455.5(STK11):c.*8C>T	STK11	Single nucleotide variant (3 prime UTR variant)	Hereditary cancer-predisposing syndrome +4 more	GConflicting classifications of pathogenicity

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Items: 24