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Items: 38

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
LOC130005193, SMPD1
(G26R)
Single nucleotide variant
(missense variant +2 more)
Inborn genetic diseases
+1 more
GUncertain significance
SMPD1
Duplication
(inframe_insertion +2 more)
not provided
+2 more
GUncertain significance
SMPD1
Deletion
(inframe_deletion +2 more)
Niemann-Pick disease, type B
+3 more
GBenign
SMPD1
Microsatellite
(inframe_insertion +2 more)
Niemann-Pick disease, type B
+2 more
GConflicting classifications of pathogenicity
SMPD1
(V36A)
Single nucleotide variant
(missense variant +2 more)
not provided
+3 more
GBenign
SMPD1
Microsatellite
(inframe_deletion +2 more)
Niemann-Pick disease, type B
+3 more
GBenign
SMPD1
Microsatellite
(inframe_deletion +2 more)
not specified
+3 more
GBenign
SMPD1
(A38fs)
Deletion
(frameshift variant +2 more)
not provided
GBenign
SMPD1
(A38V)
Single nucleotide variant
(missense variant +2 more)
not provided
+2 more
GUncertain significance
SMPD1
Single nucleotide variant
(synonymous variant +2 more)
not provided
GLikely benign
SMPD1
(R113C +1 more)
Single nucleotide variant
(missense variant +2 more)
not provided
+3 more
GConflicting classifications of pathogenicity
SMPD1
(V114M +1 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type A
+5 more
GUncertain significance
SMPD1
(V117M +1 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type B
+2 more
GConflicting classifications of pathogenicity
SMPD1
(T165I +1 more)
Single nucleotide variant
(missense variant +2 more)
not provided
GUncertain significance
SMPD1
(L203F +1 more)
Single nucleotide variant
(missense variant +2 more)
not provided
+1 more
GUncertain significance
SMPD1
Single nucleotide variant
(synonymous variant +2 more)
Niemann-Pick disease, type B
+3 more
GBenign
SMPD1
(C229F +1 more)
Single nucleotide variant
(missense variant +2 more)
not provided
GUncertain significance
SMPD1
(R230H +1 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type B
+4 more
GConflicting classifications of pathogenicity
SMPD1
(R230Q +1 more)
Single nucleotide variant
(missense variant +2 more)
not provided
+2 more
GUncertain significance
SMPD1
Single nucleotide variant
(synonymous variant +2 more)
Inborn genetic diseases
+4 more
GBenign/Likely benign
SMPD1
(R240Q +1 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type B
+3 more
GBenign/Likely benign
SMPD1
(R291H +1 more)
Single nucleotide variant
(missense variant +2 more)
Inborn genetic diseases
+5 more
GUncertain significance
SMPD1
(R296Q +1 more)
Single nucleotide variant
(missense variant +2 more)
not provided
+3 more
GConflicting classifications of pathogenicity
SMPD1
(V301I +1 more)
Single nucleotide variant
(missense variant +2 more)
not specified
+4 more
GBenign/Likely benign
SMPD1
(F332fs +2 more)
Deletion
(frameshift variant +1 more)
Niemann-Pick disease, type A
+3 more
GPathogenic
SMPD1
(P37L)
Single nucleotide variant
(synonymous variant +2 more)
Niemann-Pick disease, type A
+5 more
GBenign/Likely benign
SMPD1
(R360H +2 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+2 more
GUncertain significance
SMPD1
(R378H +2 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type B
+3 more
GConflicting classifications of pathogenicity
SMPD1
(R136Q +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
SMPD1
(A446G +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GUncertain significance
SMPD1
(A487V +3 more)
Single nucleotide variant
(missense variant +1 more)
not specified
+3 more
GConflicting classifications of pathogenicity
SMPD1
(G492S +3 more)
Single nucleotide variant
(missense variant +1 more)
Niemann-Pick disease, type A
+5 more
GUncertain significance
SMPD1
(G508R +3 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type B
+3 more
GBenign
SMPD1
(E517V +3 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type B
+4 more
GConflicting classifications of pathogenicity
SMPD1
Single nucleotide variant
(synonymous variant +2 more)
not specified
+3 more
GConflicting classifications of pathogenicity
SMPD1
(G530A +3 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type A
+4 more
GConflicting classifications of pathogenicity
SMPD1
(P533L +3 more)
Single nucleotide variant
(missense variant +2 more)
Niemann-Pick disease, type B
+3 more
GConflicting classifications of pathogenicity
SMPD1
Single nucleotide variant
(synonymous variant +2 more)
not specified
+3 more
GBenign
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