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Items: 38

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
RPGRIP1
Deletion
Retinal dystrophy
GPathogenic
RPGRIP1
(M32K)
Single nucleotide variant
(missense variant)
Leber congenital amaurosis 6
+2 more
GConflicting classifications of pathogenicity
RPGRIP1
(E45fs)
Duplication
(frameshift variant)
Retinal dystrophy
GLikely pathogenic
RPGRIP1
(R52Q)
Single nucleotide variant
(missense variant)
Leber congenital amaurosis 6
+3 more
GUncertain significance
RPGRIP1
Single nucleotide variant
(intron variant)
Cone-rod dystrophy 13
+1 more
GUncertain significance
RPGRIP1
(V90I)
Single nucleotide variant
(missense variant)
Cone-rod dystrophy 13
+4 more
GConflicting classifications of pathogenicity
RPGRIP1
(S114P)
Single nucleotide variant
(missense variant)
Leber congenital amaurosis 6
+1 more
GUncertain significance
RPGRIP1
(V131I)
Single nucleotide variant
(missense variant)
Optic atrophy
GUncertain significance
RPGRIP1
Single nucleotide variant
(synonymous variant)
Retinal dystrophy
GUncertain significance
RPGRIP1
Single nucleotide variant
(splice donor variant)
not provided
+4 more
GPathogenic/Likely pathogenic
RPGRIP1
(L353F)
Single nucleotide variant
(missense variant)
not provided
+3 more
GUncertain significance
RPGRIP1
(K369E)
Single nucleotide variant
(missense variant)
Retinal dystrophy
GUncertain significance
RPGRIP1
(N175S +2 more)
Single nucleotide variant
(missense variant)
Retinal dystrophy
GUncertain significance
RPGRIP1
(E539fs +2 more)
Deletion
(frameshift variant)
not provided
+4 more
GPathogenic/Likely pathogenic
RPGRIP1
(A547S +2 more)
Single nucleotide variant
(missense variant)
Leber congenital amaurosis 1
+5 more
GBenign/Likely benign
RPGRIP1
(L200del +2 more)
Deletion
(inframe_deletion)
Retinal dystrophy
GUncertain significance
RPGRIP1
(P585S +2 more)
Single nucleotide variant
(missense variant)
Leber congenital amaurosis 6
+4 more
GConflicting classifications of pathogenicity
RPGRIP1
(Q589H +1 more)
Single nucleotide variant
(missense variant +1 more)
Cone-rod dystrophy 13
+4 more
GBenign/Likely benign
RPGRIP1
(P292S +1 more)
Single nucleotide variant
(missense variant +1 more)
Retinal dystrophy
GLikely pathogenic
RPGRIP1
(P316H +1 more)
Single nucleotide variant
(missense variant +1 more)
Retinal dystrophy
GLikely pathogenic
RPGRIP1
Single nucleotide variant
(synonymous variant +1 more)
Cone-rod dystrophy 13
+3 more
GConflicting classifications of pathogenicity
RPGRIP1
Deletion
(intron variant)
Retinal dystrophy
+3 more
GConflicting classifications of pathogenicity
RPGRIP1
(A479G +1 more)
Single nucleotide variant
(missense variant +1 more)
Retinal dystrophy
+3 more
GUncertain significance
RPGRIP1
(R852* +1 more)
Single nucleotide variant
(nonsense +1 more)
not provided
+3 more
GPathogenic/Likely pathogenic
RPGRIP1
(R852Q +1 more)
Single nucleotide variant
(missense variant +1 more)
Cone-rod dystrophy 13
+5 more
GConflicting classifications of pathogenicity
RPGRIP1
(I872V +1 more)
Single nucleotide variant
(missense variant +1 more)
Cone-rod dystrophy 13
+1 more
GUncertain significance
RPGRIP1
(R890Q +1 more)
Single nucleotide variant
(missense variant +1 more)
Retinal dystrophy
+2 more
GUncertain significance
RPGRIP1
(N907* +4 more)
Duplication
(nonsense)
Cone-rod dystrophy 13
+3 more
GPathogenic/Likely pathogenic
RPGRIP1
(E117K +4 more)
Single nucleotide variant
(missense variant)
Retinal dystrophy
+2 more
GUncertain significance
RPGRIP1
Single nucleotide variant
(splice acceptor variant +1 more)
Leber congenital amaurosis 6
+1 more
GLikely pathogenic
RPGRIP1
(D1114G +4 more)
Single nucleotide variant
(missense variant)
Leber congenital amaurosis 6
+4 more
GBenign/Likely benign
RPGRIP1
(I1120V +4 more)
Single nucleotide variant
(missense variant)
Retinal dystrophy
+4 more
GUncertain significance
RPGRIP1
(P1152S +4 more)
Single nucleotide variant
(missense variant)
Cone-rod dystrophy 13
+1 more
GUncertain significance
RPGRIP1
(K1221N +4 more)
Single nucleotide variant
(missense variant)
Retinal dystrophy
GUncertain significance
RPGRIP1
(E1279del +4 more)
Deletion
(inframe_deletion)
not specified
+3 more
GUncertain significance
RPGRIP1
(E1279fs +4 more)
Deletion
(frameshift variant)
Retinal dystrophy
GUncertain significance
RPGRIP1
Deletion
Retinal dystrophy
GPathogenic
RPGRIP1
Deletion
Retinal dystrophy
GPathogenic
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