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Items: 32

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
ASPA, SPATA22
Single nucleotide variant
(5 prime UTR variant +1 more)
Spongy degeneration of central nervous system
GUncertain significance
ASPA, SPATA22
(I16T)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
GPathogenic/Likely pathogenic
ASPA, SPATA22
(G27R)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
+2 more
GPathogenic/Likely pathogenic
ASPA, SPATA22
(L30P)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
+1 more
GLikely pathogenic
ASPA, SPATA22
(N54K)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
GPathogenic/Likely pathogenic
ASPA, SPATA22
(R71H)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
+2 more
GPathogenic/Likely pathogenic
ASPA, SPATA22
(N77S)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
GConflicting classifications of pathogenicity
ASPA, SPATA22
Single nucleotide variant
(intron variant +1 more)
Spongy degeneration of central nervous system
+1 more
GPathogenic/Likely pathogenic
SPATA22, ASPA
(M82fs)
Duplication
(frameshift variant +1 more)
not provided
+3 more
GPathogenic/Likely pathogenic
ASPA, SPATA22
(D114Y)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
+1 more
GPathogenic/Likely pathogenic
ASPA, SPATA22
(I143V)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
+1 more
GConflicting classifications of pathogenicity
ASPA, SPATA22
(I143F)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
+1 more
GPathogenic/Likely pathogenic
ASPA, SPATA22
(S146fs)
Deletion
(frameshift variant +1 more)
Spongy degeneration of central nervous system
+1 more
GPathogenic/Likely pathogenic
ASPA, SPATA22
(R168C)
Single nucleotide variant
(missense variant +1 more)
not provided
+2 more
GPathogenic/Likely pathogenic
SPATA22, ASPA
(R168H)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
+1 more
GPathogenic/Likely pathogenic
ASPA, SPATA22
(I170T)
Single nucleotide variant
(missense variant +1 more)
not specified
+1 more
GConflicting classifications of pathogenicity
ASPA, SPATA22
(P181T)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
+2 more
GPathogenic/Likely pathogenic
SPATA22, ASPA
Single nucleotide variant
(intron variant +1 more)
Spongy degeneration of central nervous system
+2 more
GPathogenic/Likely pathogenic
ASPA, SPATA22
(K213E)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
+2 more
GConflicting classifications of pathogenicity
ASPA, SPATA22
(C218*)
Single nucleotide variant
(nonsense +1 more)
Spongy degeneration of central nervous system
+1 more
GPathogenic
ASPA, SPATA22
Single nucleotide variant
(synonymous variant +1 more)
not specified
+3 more
GBenign/Likely benign
ASPA, SPATA22
(Y231*)
Single nucleotide variant
(nonsense +1 more)
Spongy degeneration of central nervous system
+3 more
GPathogenic
ASPA, SPATA22
(D249V)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
GPathogenic/Likely pathogenic
SPATA22, ASPA
Single nucleotide variant
(synonymous variant +1 more)
Spongy degeneration of central nervous system
GConflicting classifications of pathogenicity
ASPA, SPATA22
(I270T)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
GUncertain significance
ASPA, SPATA22
(G274R)
Single nucleotide variant
(missense variant +1 more)
Canavan Disease, Familial Form
+2 more
GPathogenic/Likely pathogenic
ASPA, SPATA22
(V278fs)
Deletion
(frameshift variant +1 more)
Spongy degeneration of central nervous system
GPathogenic/Likely pathogenic
ASPA, SPATA22
(E285A)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
+3 more
GPathogenic
ASPA, SPATA22
(A287T)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
+2 more
GPathogenic/Likely pathogenic
ASPA, SPATA22
(E293fs)
Microsatellite
(frameshift variant +1 more)
Spongy degeneration of central nervous system
+1 more
GPathogenic/Likely pathogenic
ASPA, SPATA22
Single nucleotide variant
(synonymous variant +1 more)
Spongy degeneration of central nervous system
GConflicting classifications of pathogenicity
ASPA, SPATA22
(A305E)
Single nucleotide variant
(missense variant +1 more)
Spongy degeneration of central nervous system
+3 more
GPathogenic
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