"Genome Diagnostics Laboratory, The Hospital for Sick Children"[submit - ClinVar - NCBI

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Items: 12

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 308059	NM_033360.4(KRAS):c.*4200T>A	KRAS	Single nucleotide variant (3 prime UTR variant)	not provided +2 more	GBenign/Likely benign
Select item 308084	NM_033360.4(KRAS):c.*2626T>G	KRAS	Single nucleotide variant (3 prime UTR variant)	not provided +3 more	GBenign/Likely benign
Select item 308116	NM_033360.4(KRAS):c.*671C>T	KRAS	Single nucleotide variant (3 prime UTR variant)	not provided +2 more	GConflicting classifications of pathogenicity
Select item 308118	NM_033360.4(KRAS):c.*633T>C	KRAS	Single nucleotide variant (3 prime UTR variant)	Noonan syndrome +2 more	GBenign/Likely benign
Select item 308119	NM_033360.4(KRAS):c.*525T>C	KRAS	Single nucleotide variant (3 prime UTR variant)	Noonan syndrome and Noonan-related syndrome +1 more	GConflicting classifications of pathogenicity
Select item 40467	NM_033360.4(KRAS):c.*298T>G	KRAS	Single nucleotide variant (3 prime UTR variant)	Noonan syndrome and Noonan-related syndrome +3 more	GBenign/Likely benign
Select item 45129	NM_004985.5(KRAS):c.528GAA[1] (p.Lys180del)	KRAS (K180del)	Microsatellite (3 prime UTR variant +1 more)	RASopathy	GBenign FDA Recognized database
Select item 45115	NM_004985.5(KRAS):c.182A>G (p.Gln61Arg)	KRAS (Q61R)	Single nucleotide variant (missense variant)	RASopathy +3 more	GConflicting classifications of pathogenicity OOncogenic
Select item 12589	NM_004985.5(KRAS):c.40G>A (p.Val14Ile)	KRAS (V14I)	Single nucleotide variant (missense variant)	Noonan syndrome	GPathogenic FDA Recognized database
Select item 12580	NM_004985.5(KRAS):c.38G>A (p.Gly13Asp)	KRAS (G13D)	Single nucleotide variant (missense variant)	RASopathy +6 more	GPathogenic OOncogenic
Select item 1334243	NM_004985.5(KRAS):c.-14G>C	KRAS, LOC130007561	Single nucleotide variant (5 prime UTR variant +1 more)	Noonan syndrome and Noonan-related syndrome	GUncertain significance
Select item 1334244	NM_004985.5(KRAS):c.-167_-153dup	KRAS, LOC130007561	Duplication (5 prime UTR variant)	Noonan syndrome and Noonan-related syndrome	GUncertain significance