"GeneDx"[submitter] AND "TET2"[gene] - ClinVar

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Items: 35

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 58033	GRCh38/hg38 4q22.3-28.3(chr4:96092893-136410207)x3	LOC129993082, LOC129993083 +661 more	Copy number gain	See cases	GPathogenic
Select item 1234506	NM_001127208.3(TET2):c.-46-63ATAG[4]	TET2, TET2-AS1	Microsatellite (intron variant)	not specified +1 more	GBenign
Select item 1700440	NM_001127208.3(TET2):c.95C>T (p.Thr32Ile)	TET2, TET2-AS1 (T32I)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 3364189	NM_001127208.3(TET2):c.301C>A (p.Pro101Thr)	TET2, TET2-AS1 (P101T)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 135321	NM_001127208.3(TET2):c.652G>A (p.Val218Met)	TET2, TET2-AS1 (V218M)	Single nucleotide variant (missense variant)	not provided	GBenign
Select item 1329593	NM_001127208.3(TET2):c.744C>A (p.His248Gln)	TET2, TET2-AS1 (H248Q)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 135318	NM_001127208.3(TET2):c.1285G>A (p.Gly429Arg)	TET2, TET2-AS1 (G429R)	Single nucleotide variant (missense variant)	not provided +1 more	GUncertain significance
Select item 1318623	NM_001127208.3(TET2):c.1924C>T (p.Gln642Ter)	TET2, TET2-AS1 (Q642*)	Single nucleotide variant (nonsense)	not provided	GUncertain significance
Select item 1708755	NM_001127208.3(TET2):c.2084T>C (p.Met695Thr)	TET2-AS1, TET2 (M695T)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 1318869	NM_001127208.3(TET2):c.2216_2264dup (p.Glu755delinsAspSerLysProAlaThrAlaAlaLysIleThrAsnLysGluTer)	TET2, TET2-AS1	Duplication (nonsense)	not provided	GUncertain significance
Select item 1318951	NM_001127208.3(TET2):c.2230C>T (p.Gln744Ter)	TET2, TET2-AS1 (Q744*)	Single nucleotide variant (nonsense)	not provided	GUncertain significance
Select item 135303	NM_001127208.3(TET2):c.2429A>G (p.Gln810Arg)	TET2, TET2-AS1 (Q810R)	Single nucleotide variant (missense variant)	not provided +1 more	GConflicting classifications of pathogenicity
Select item 432521	NM_001127208.3(TET2):c.2964_2967dup (p.His990fs)	TET2, TET2-AS1 (H990fs)	Duplication (frameshift variant)	not provided	GUncertain significance
Select item 1711916	NM_001127208.3(TET2):c.3223del (p.Asp1075fs)	TET2, TET2-AS1 (D1075fs)	Deletion (frameshift variant)	not provided	GUncertain significance
Select item 2662492	NM_001127208.3(TET2):c.3401G>C (p.Arg1134Thr)	TET2, TET2-AS1 (R1134T)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 135327	NM_001127208.3(TET2):c.3409+42G>T	TET2, TET2-AS1 (E1151*)	Single nucleotide variant (nonsense +1 more)	not provided	GUncertain significance
Select item 2184873	NM_001127208.3(TET2):c.3583A>G (p.Ile1195Val)	TET2, TET2-AS1 (I1195V)	Single nucleotide variant (missense variant)	not provided	GConflicting classifications of pathogenicity
Select item 1251249	NM_001127208.3(TET2):c.3594+200T>G	TET2, TET2-AS1	Single nucleotide variant (intron variant)	not provided	GBenign
Select item 1711917	NM_001127208.3(TET2):c.3821A>T (p.Gln1274Leu)	TET2, TET2-AS1 (Q1274L)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 1318592	NM_001127208.3(TET2):c.4042C>T (p.Gln1348Ter)	TET2, TET2-AS1 (Q1348*)	Single nucleotide variant (nonsense)	not provided	GUncertain significance
Select item 430399	NM_001127208.3(TET2):c.4145A>G (p.His1382Arg)	TET2-AS1, TET2 (H1382R)	Single nucleotide variant (genic downstream transcript variant +1 more)	not provided	GUncertain significance
Select item 1711926	NM_001127208.3(TET2):c.4276G>A (p.Val1426Met)	TET2, TET2-AS1 (V1426M)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 1318626	NM_001127208.3(TET2):c.4354C>T (p.Arg1452Ter)	TET2, TET2-AS1 (R1452*)	Single nucleotide variant (nonsense)	not provided	GConflicting classifications of pathogenicity
Select item 1221839	NM_001127208.3(TET2):c.4538-113C>T	TET2, TET2-AS1	Single nucleotide variant (intron variant)	not provided	GBenign
Select item 3364379	NM_001127208.3(TET2):c.4603C>T (p.Pro1535Ser)	TET2, TET2-AS1 (P1535S)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 1318591	NM_001127208.3(TET2):c.4624C>T (p.Gln1542Ter)	TET2-AS1, TET2 (Q1542*)	Single nucleotide variant (nonsense)	not provided	GUncertain significance
Select item 1315792	NM_001127208.3(TET2):c.4879C>T (p.Gln1627Ter)	TET2, TET2-AS1 (Q1627*)	Single nucleotide variant (nonsense)	not provided	GUncertain significance
Select item 3368201	NM_001127208.3(TET2):c.5004dup (p.Lys1669Ter)	TET2, TET2-AS1 (K1669*)	Duplication (nonsense)	not provided	GUncertain significance
Select item 135287	NM_001127208.3(TET2):c.5284A>G (p.Ile1762Val)	TET2, TET2-AS1 (I1762V)	Single nucleotide variant (missense variant)	not specified +1 more	GBenign
Select item 1316492	NM_001127208.3(TET2):c.5834A>G (p.His1945Arg)	TET2, TET2-AS1 (H1945R)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 1318499	NM_001127208.3(TET2):c.6002_*30del (p.Arg2000_Tyr2001insTer)	TET2, TET2-AS1	Deletion (nonsense)	not provided	GUncertain significance
Select item 1250875	NM_001127208.3(TET2):c.329_330dup	TET2, TET2-AS1	Duplication (3 prime UTR variant)	not provided	GBenign
Select item 3360917	NM_001127208.3(TET2):c.3677T>C (p.Ile1226Thr)	TET2 (I1226T)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 3359863	NM_001127208.3(TET2):c.3011A>T (p.Lys1004Ile)	TET2 (K1004I)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 3359485	NM_001127208.3(TET2):c.3473C>T (p.Ala1158Val)	TET2 (A1158V)	Single nucleotide variant (missense variant +1 more)	not provided	GUncertain significance

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Items: 35