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Items: 23

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
AAMDC, ACER3
+355 more
Copy number loss
See cases
GPathogenic
PAK1
(Q447H +11 more)
Single nucleotide variant
(missense variant +2 more)
not provided
GUncertain significance
PAK1
(I393T +6 more)
Single nucleotide variant
(missense variant +2 more)
See cases
+2 more
GPathogenic/Likely pathogenic
PAK1
(P364S +7 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
PAK1
(A356T +7 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
PAK1
Single nucleotide variant
(intron variant)
Intellectual developmental disorder with macrocephaly, seizures, and speech delay
+1 more
GBenign
PAK1
(E336G +6 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
PAK1
(E176Q +4 more)
Single nucleotide variant
(missense variant +2 more)
not provided
GUncertain significance
PAK1
(S161I +3 more)
Single nucleotide variant
(missense variant +2 more)
not provided
GUncertain significance
PAK1
Single nucleotide variant
(splice donor variant +1 more)
not provided
GUncertain significance
PAK1
(R160* +3 more)
Single nucleotide variant
(nonsense +3 more)
not provided
GUncertain significance
PAK1
(V106G +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
PAK1
(M143V +2 more)
Single nucleotide variant
(missense variant +2 more)
not provided
GLikely pathogenic
PAK1
(S133L +2 more)
Single nucleotide variant
(missense variant +2 more)
not provided
GUncertain significance
PAK1
(V127M +2 more)
Single nucleotide variant
(missense variant +2 more)
not provided
GConflicting classifications of pathogenicity
PAK1
(P128L +2 more)
Single nucleotide variant
(missense variant +2 more)
PAK1-related disorder
+2 more
GPathogenic
PAK1
(P121S +2 more)
Single nucleotide variant
(missense variant +2 more)
Intellectual developmental disorder with macrocephaly, seizures, and speech delay
+1 more
GPathogenic/Likely pathogenic
PAK1
(E95A)
Single nucleotide variant
(missense variant +3 more)
not provided
GUncertain significance
PAK1
(N64D +1 more)
Single nucleotide variant
(missense variant +2 more)
not provided
GUncertain significance
PAK1
(P15S)
Single nucleotide variant
(missense variant +2 more)
not provided
GUncertain significance
PAK1
(L159* +3 more)
Single nucleotide variant
(nonsense +2 more)
not provided
GUncertain significance
PAK1
(P104L +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
PAK1
Single nucleotide variant
(splice donor variant +1 more)
not provided
GUncertain significance
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