"GeneDx"[submitter] AND "KRAS"[gene] - ClinVar - NCBI

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	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 40467	NM_033360.4(KRAS):c.*298T>G	KRAS	Single nucleotide variant (3 prime UTR variant)	Noonan syndrome and Noonan-related syndrome +3 more	GBenign/Likely benign
Select item 385525	NM_033360.4(KRAS):c.*134C>T	KRAS	Single nucleotide variant (3 prime UTR variant)	not specified	GLikely benign
Select item 561725	NM_033360.4(KRAS):c.*110G>T	KRAS (V186L)	Single nucleotide variant (3 prime UTR variant +1 more)	not provided	GUncertain significance
Select item 2914356	NM_004985.5(KRAS):c.550_551del (p.Lys184fs)	KRAS (K184fs)	Deletion (3 prime UTR variant +1 more)	RASopathy +1 more	GUncertain significance
Select item 45129	NM_004985.5(KRAS):c.528GAA[1] (p.Lys180del)	KRAS (K180del)	Microsatellite (3 prime UTR variant +1 more)	RASopathy	GBenign FDA Recognized database
Select item 41449	NM_004985.5(KRAS):c.519T>C (p.Asp173=)	KRAS	Single nucleotide variant (3 prime UTR variant +1 more)	RASopathy	GBenign FDA Recognized database
Select item 180859	NM_004985.5(KRAS):c.508A>T (p.Met170Leu)	KRAS (M170L)	Single nucleotide variant (missense variant +1 more)	RASopathy	GUncertain significance FDA Recognized database
Select item 3373678	NM_004985.5(KRAS):c.488T>C (p.Ile163Thr)	KRAS (I163T)	Single nucleotide variant (3 prime UTR variant +1 more)	not provided	GUncertain significance
Select item 1803471	NM_004985.5(KRAS):c.481C>T (p.Arg161Ter)	KRAS (R161*)	Single nucleotide variant (3 prime UTR variant +1 more)	not provided	GUncertain significance
Select item 2662065	NM_004985.5(KRAS):c.479T>G (p.Val160Gly)	KRAS (V160G)	Single nucleotide variant (3 prime UTR variant +1 more)	not provided	GUncertain significance
Select item 12595	NM_033360.4(KRAS):c.*22C>G	KRAS (F156L)	Single nucleotide variant (3 prime UTR variant +1 more)	RASopathy +2 more	GPathogenic
Select item 163758	NM_004985.5(KRAS):c.466T>A (p.Phe156Ile)	KRAS (F156I)	Single nucleotide variant (3 prime UTR variant +1 more)	Noonan syndrome +3 more	GPathogenic
Select item 45127	NM_004985.5(KRAS):c.466T>G (p.Phe156Val)	KRAS (F156V)	Single nucleotide variant (3 prime UTR variant +1 more)	not provided +1 more	GPathogenic/Likely pathogenic
Select item 40465	NM_004985.5(KRAS):c.458A>G (p.Asp153Gly)	KRAS (D153G)	Single nucleotide variant (3 prime UTR variant +1 more)	RASopathy +2 more	GPathogenic/Likely pathogenic
Select item 12587	NM_004985.5(KRAS):c.458A>T (p.Asp153Val)	KRAS (D153V)	Single nucleotide variant (3 prime UTR variant +1 more)	Noonan syndrome	GPathogenic FDA Recognized database
Select item 561755	NM_033360.4(KRAS):c.*11G>A	KRAS (D153N)	Single nucleotide variant (3 prime UTR variant +1 more)	not provided	GPathogenic
Select item 1239850	NM_004985.5(KRAS):c.456T>G (p.Val152=)	KRAS	Single nucleotide variant (3 prime UTR variant +1 more)	RASopathy +1 more	GLikely benign
Select item 1264725	NM_004985.5(KRAS):c.453T>C (p.Gly151=)	KRAS	Single nucleotide variant (3 prime UTR variant +1 more)	RASopathy +1 more	GLikely benign
Select item 40464	NM_004985.5(KRAS):c.451-9G>A	KRAS	Single nucleotide variant (intron variant)	not specified +3 more	GBenign
Select item 378062	NM_033360.4(KRAS):c.5-11A>G	KRAS	Single nucleotide variant (intron variant)	RASopathy +2 more	GLikely benign
Select item 138060	NM_004985.5(KRAS):c.451-14T>C	KRAS	Single nucleotide variant (intron variant)	RASopathy	GLikely benign FDA Recognized database
Select item 379556	NM_033360.4(KRAS):c.5-18A>G	KRAS	Single nucleotide variant (intron variant)	not provided +13 more	GBenign/Likely benign
Select item 561623	NM_033360.4(KRAS):c.5-240G>A	KRAS	Single nucleotide variant (intron variant)	not provided	GLikely benign
Select item 561815	NM_033360.4(KRAS):c.4+287A>G	KRAS	Single nucleotide variant (intron variant)	not provided	GBenign
Select item 1192108	NM_004985.5(KRAS):c.451-5327G>A	KRAS	Single nucleotide variant (intron variant)	not provided	GLikely benign
Select item 46542	NM_004985.5(KRAS):c.451-5535A>C	KRAS (M189L)	Single nucleotide variant (missense variant +1 more)	not provided +1 more	GConflicting classifications of pathogenicity
Select item 46541	NM_004985.5(KRAS):c.451-5560T>A	KRAS (C180*)	Single nucleotide variant (nonsense +1 more)	not specified +2 more	GConflicting classifications of pathogenicity
Select item 46540	NM_004985.5(KRAS):c.451-5565G>A	KRAS (G179S)	Single nucleotide variant (missense variant +1 more)	not specified +2 more	GBenign/Likely benign
Select item 372611	NM_004985.5(KRAS):c.451-5588T>C	KRAS (I171T)	Single nucleotide variant (missense variant +1 more)	not provided	GUncertain significance
Select item 386200	NM_004985.5(KRAS):c.451-5604T>C	KRAS (Y166H)	Single nucleotide variant (missense variant +1 more)	not specified +2 more	GConflicting classifications of pathogenicity
Select item 46539	NM_004985.5(KRAS):c.451-5604T>A	KRAS (Y166N)	Single nucleotide variant (missense variant +1 more)	not provided	GLikely benign
Select item 46538	NM_004985.5(KRAS):c.451-5617=	KRAS	Single nucleotide variant (no sequence alteration +1 more)	Cardiovascular phenotype +2 more	GBenign
Select item 561660	NM_033360.4(KRAS):c.451-224T>A	KRAS	Single nucleotide variant (intron variant)	not provided	GLikely benign
Select item 1267974	NM_004985.5(KRAS):c.450+304_450+322del	KRAS	Deletion (intron variant)	not provided	GBenign
Select item 1253667	NM_004985.5(KRAS):c.450+306_450+322del	KRAS	Deletion (intron variant)	not provided	GBenign
Select item 1246048	NM_004985.5(KRAS):c.450+298_450+322del	KRAS	Deletion (intron variant)	not provided	GBenign
Select item 1244733	NM_004985.5(KRAS):c.450+300_450+322del	KRAS	Deletion (intron variant)	not provided	GBenign
Select item 1233405	NM_004985.5(KRAS):c.450+308_450+322del	KRAS	Deletion (intron variant)	not provided	GBenign
Select item 1219169	NM_004985.5(KRAS):c.450+304T>A	KRAS	Single nucleotide variant (intron variant)	not provided	GLikely benign
Select item 1276764	NM_004985.5(KRAS):c.450+298T>A	KRAS	Single nucleotide variant (intron variant)	not provided	GBenign
Select item 1212481	NM_004985.5(KRAS):c.450+296T>A	KRAS	Single nucleotide variant (intron variant)	not provided	GLikely benign
Select item 1247750	NM_033360.4(KRAS):c.450+92A>G	KRAS	Single nucleotide variant (intron variant)	not provided	GBenign
Select item 1234106	NM_033360.4(KRAS):c.450+40A>G	KRAS	Single nucleotide variant (intron variant)	not provided	GBenign
Select item 515085	NM_033360.4(KRAS):c.450+16A>G	KRAS	Single nucleotide variant (intron variant)	not specified	GLikely benign
Select item 391031	NM_033360.4(KRAS):c.450+13G>A	KRAS	Single nucleotide variant (intron variant)	not provided	GLikely benign
Select item 31941	NM_033360.4(KRAS):c.439A>G (p.Lys147Glu)	KRAS (K147E)	Single nucleotide variant (missense variant)	not provided	GPathogenic/Likely pathogenic
Select item 3378021	NM_004985.5(KRAS):c.413G>C (p.Gly138Ala)	KRAS (G138A)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 1218871	NM_004985.5(KRAS):c.411T>C (p.Tyr137=)	KRAS	Single nucleotide variant (synonymous variant)	RASopathy +1 more	GLikely benign
Select item 503538	NM_004985.5(KRAS):c.407G>A (p.Ser136Asn)	KRAS (S136N)	Single nucleotide variant (missense variant)	RASopathy +2 more	GUncertain significance
Select item 1677688	NM_004985.5(KRAS):c.401C>G (p.Ala134Gly)	KRAS (A134G)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 180861	NM_033360.4(KRAS):c.389C>T (p.Ala130Val)	KRAS (A130V)	Single nucleotide variant (missense variant)	Noonan syndrome 3 +15 more	GUncertain significance
Select item 2498003	NM_004985.5(KRAS):c.380C>G (p.Thr127Arg)	KRAS (T127R)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 452452	NM_033360.4(KRAS):c.371C>T (p.Thr124Ile)	KRAS (T124I)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 40460	NM_033360.4(KRAS):c.355G>A (p.Asp119Asn)	KRAS (D119N)	Single nucleotide variant (missense variant)	Autoimmune lymphoproliferative syndrome type 4 +5 more	GLikely pathogenic
Select item 156338	NM_033360.4(KRAS):c.347A>G (p.Asn116Ser)	KRAS (N116S)	Single nucleotide variant (missense variant)	not provided	GLikely pathogenic
Select item 1219824	NM_004985.5(KRAS):c.346A>C (p.Asn116His)	KRAS (N116H)	Single nucleotide variant (missense variant)	not provided	GPathogenic
Select item 1189384	NM_004985.5(KRAS):c.291-128T>G	KRAS	Single nucleotide variant (intron variant)	not provided	GLikely benign
Select item 1292363	NM_004985.5(KRAS):c.291-162A>C	KRAS	Single nucleotide variant (intron variant)	not provided	GBenign
Select item 561928	NM_033360.4(KRAS):c.291-311A>G	KRAS	Single nucleotide variant (intron variant)	not provided	GLikely benign
Select item 1279239	NM_033360.4(KRAS):c.290+97A>T	KRAS	Single nucleotide variant (intron variant)	not provided	GBenign
Select item 1263524	NM_033360.4(KRAS):c.290+97A>C	KRAS	Single nucleotide variant (intron variant)	not provided	GBenign
Select item 1253268	NM_033360.4(KRAS):c.290+74T>G	KRAS	Single nucleotide variant (intron variant)	not provided	GBenign
Select item 2061689	NM_004985.5(KRAS):c.283C>A (p.His95Asn)	KRAS (H95N)	Single nucleotide variant (missense variant)	RASopathy +1 more	GUncertain significance
Select item 1803539	NM_004985.5(KRAS):c.283C>T (p.His95Tyr)	KRAS (H95Y)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 227471	NM_004985.5(KRAS):c.264A>G (p.Lys88=)	KRAS	Single nucleotide variant (synonymous variant)	not specified +3 more	GConflicting classifications of pathogenicity
Select item 1318518	NM_004985.5(KRAS):c.250A>G (p.Ile84Val)	KRAS (I84V)	Single nucleotide variant (missense variant)	not provided +1 more	GUncertain significance
Select item 40456	NM_033360.4(KRAS):c.249C>T (p.Ala83=)	KRAS	Single nucleotide variant (synonymous variant)	RASopathy +2 more	GConflicting classifications of pathogenicity
Select item 1191328	NM_004985.5(KRAS):c.229G>A (p.Gly77Ser)	KRAS (G77S)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 228267	NM_004985.5(KRAS):c.211T>G (p.Tyr71Asp)	KRAS (Y71D)	Single nucleotide variant (missense variant)	Cardio-facio-cutaneous syndrome +1 more	GLikely pathogenic
Select item 45118	NM_004985.5(KRAS):c.198A>G (p.Ala66=)	KRAS	Single nucleotide variant (synonymous variant)	Noonan syndrome +3 more	GConflicting classifications of pathogenicity
Select item 180857	NM_004985.5(KRAS):c.184GAG[1] (p.Glu63del)	KRAS (E63del)	Microsatellite (inframe_deletion)	RASopathy	GLikely pathogenic
Select item 163766	NM_004985.5(KRAS):c.179G>T (p.Gly60Val)	KRAS (G60V)	Single nucleotide variant (missense variant)	not provided +1 more	GPathogenic/Likely pathogenic
Select item 12597	NM_033360.4(KRAS):c.178G>A (p.Gly60Ser)	KRAS (G60S)	Single nucleotide variant (missense variant)	Cardiofaciocutaneous syndrome 2 +3 more	GPathogenic
Select item 12586	NM_004985.5(KRAS):c.178G>C (p.Gly60Arg)	KRAS (G60R)	Single nucleotide variant (missense variant)	Cardio-facio-cutaneous syndrome	GPathogenic FDA Recognized database
Select item 12588	NM_004985.5(KRAS):c.173C>T (p.Thr58Ile)	KRAS (T58I)	Single nucleotide variant (missense variant)	Noonan syndrome	GPathogenic FDA Recognized database
Select item 2575733	NM_004985.5(KRAS):c.148A>C (p.Thr50Pro)	KRAS (T50P)	Single nucleotide variant (missense variant)	not provided	GLikely pathogenic
Select item 180858	NM_033360.4(KRAS):c.148A>T (p.Thr50Ser)	KRAS (T50S)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 2444789	NM_004985.5(KRAS):c.121A>G (p.Arg41Gly)	KRAS (R41G)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 477690	NM_033360.4(KRAS):c.112-10C>T	KRAS	Single nucleotide variant (intron variant)	not provided +1 more	GLikely benign
Select item 561662	NM_033360.4(KRAS):c.111+239A>G	KRAS	Single nucleotide variant (intron variant)	not provided	GLikely benign
Select item 1294373	NM_004985.5(KRAS):c.111+190A>T	KRAS	Single nucleotide variant (intron variant)	not provided	GBenign
Select item 163768	NM_004985.5(KRAS):c.108A>G (p.Ile36Met)	KRAS (I36M)	Single nucleotide variant (missense variant)	not provided +5 more	GPathogenic/Likely pathogenic
Select item 2505054	NM_004985.5(KRAS):c.106A>G (p.Ile36Val)	KRAS (I36V)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 40454	NM_004985.5(KRAS):c.101C>T (p.Pro34Leu)	KRAS (P34L)	Single nucleotide variant (missense variant)	Noonan syndrome	GPathogenic FDA Recognized database
Select item 12590	NM_004985.5(KRAS):c.101C>G (p.Pro34Arg)	KRAS (P34R)	Single nucleotide variant (missense variant)	RASopathy +7 more	GPathogenic/Likely pathogenic
Select item 2506804	NM_004985.5(KRAS):c.98A>G (p.Asp33Gly)	KRAS (D33G)	Single nucleotide variant (missense variant)	RASopathy +1 more	GUncertain significance
Select item 195234	NM_033360.4(KRAS):c.93A>G (p.Glu31=)	KRAS	Single nucleotide variant (synonymous variant)	RASopathy +2 more	GConflicting classifications of pathogenicity
Select item 138061	NM_033360.4(KRAS):c.90C>T (p.Asp30=)	KRAS	Single nucleotide variant (synonymous variant)	RASopathy	GLikely benign FDA Recognized database
Select item 195235	NM_033360.4(KRAS):c.76A>T (p.Asn26Tyr)	KRAS (N26Y)	Single nucleotide variant (missense variant)	not provided	GUncertain significance
Select item 180860	NM_033360.4(KRAS):c.68T>G (p.Leu23Arg)	KRAS (L23R)	Single nucleotide variant (missense variant)	not provided	GLikely pathogenic
Select item 40453	NM_033360.4(KRAS):c.65A>T (p.Gln22Leu)	KRAS (Q22L)	Single nucleotide variant (missense variant)	not provided	GLikely pathogenic
Select item 40452	NM_004985.5(KRAS):c.65A>G (p.Gln22Arg)	KRAS (Q22R)	Single nucleotide variant (missense variant)	Noonan syndrome	GPathogenic FDA Recognized database
Select item 452631	NM_033360.4(KRAS):c.44G>T (p.Gly15Val)	KRAS (G15V)	Single nucleotide variant (missense variant)	not provided	GLikely pathogenic
Select item 12589	NM_004985.5(KRAS):c.40G>A (p.Val14Ile)	KRAS (V14I)	Single nucleotide variant (missense variant)	Noonan syndrome	GPathogenic FDA Recognized database
Select item 45123	NM_004985.5(KRAS):c.37G>T (p.Gly13Cys)	KRAS (G13C)	Single nucleotide variant (missense variant)	Autoimmune lymphoproliferative syndrome type 4 +3 more	GPathogenic/Likely pathogenic
Select item 12583	NM_004985.5(KRAS):c.35G>T (p.Gly12Val)	KRAS (G12V)	Single nucleotide variant (missense variant)	Juvenile myelomonocytic leukemia +5 more	GPathogenic OOncogenic
Select item 12582	NM_004985.5(KRAS):c.35G>A (p.Gly12Asp)	KRAS (G12D)	Single nucleotide variant (missense variant)	RASopathy +6 more	GPathogenic/Likely pathogenic OOncogenic
Select item 12584	NM_004985.5(KRAS):c.34G>A (p.Gly12Ser)	KRAS (G12S)	Single nucleotide variant (missense variant)	RASopathy +4 more	GPathogenic OOncogenic
Select item 424018	NM_033360.4(KRAS):c.31_32insGGC (p.Ala11delinsGlyPro)	KRAS	Insertion (inframe_indel)	not provided	GPathogenic
Select item 45119	NM_004985.5(KRAS):c.24A>G (p.Val8=)	KRAS	Single nucleotide variant (synonymous variant)	RASopathy	GLikely benign FDA Recognized database

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