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Items: 90

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
DENND5A, DNHD1
+723 more
Copy number gain
See cases
GPathogenic
ANO9, AP2A2
+266 more
Copy number gain
See cases
GPathogenic
DEAF1
(Q537* +2 more)
Single nucleotide variant
(nonsense)
Inborn genetic diseases
+1 more
GUncertain significance
DEAF1
(R530C +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1
(F527del +2 more)
Deletion
(inframe_deletion)
not provided
GUncertain significance
DEAF1
(E268D +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1
(G266V +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1, LOC126861109
(A255V +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1, LOC126861109
(K250E +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1, LOC126861109
(R242* +2 more)
Single nucleotide variant
(nonsense)
not provided
GPathogenic/Likely pathogenic
DEAF1, LOC126861109
Single nucleotide variant
(synonymous variant)
not provided
GBenign
LOC126861109, DEAF1
(Y213H +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1, LOC126861109
(E207fs +2 more)
Insertion
(frameshift variant)
not provided
GUncertain significance
DEAF1, LOC126861109
(P197A +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1, LOC126861109
(A436V +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1, LOC126861109
(K193E +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1, LOC126861109
(A185V +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1, LOC126861109
Single nucleotide variant
(intron variant)
not provided
GBenign
DEAF1
(A162S +2 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
DEAF1
(Q160* +2 more)
Single nucleotide variant
(nonsense)
not provided
GLikely pathogenic
DEAF1
(F282Y +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1
(G126R +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1
(A366T +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1
(P123fs +2 more)
Microsatellite
(frameshift variant)
not provided
+1 more
GConflicting classifications of pathogenicity
DEAF1
(A110T +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1
Indel
(inframe_indel)
not provided
GUncertain significance
DEAF1
(S249L +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
DEAF1
Single nucleotide variant
(splice acceptor variant)
not provided
GLikely pathogenic
DEAF1
Single nucleotide variant
(intron variant)
not provided
GLikely pathogenic
DEAF1
(A327T +1 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
+2 more
GConflicting classifications of pathogenicity
DEAF1
(S318A +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GUncertain significance
DEAF1
(K305E +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(K304E +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(R303L +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(F297S +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GConflicting classifications of pathogenicity
DEAF1
Deletion
(splice donor variant)
not provided
GLikely pathogenic
DEAF1
(C279W +2 more)
Single nucleotide variant
(missense variant)
not provided
GConflicting classifications of pathogenicity
DEAF1
(Q26* +1 more)
Single nucleotide variant
(nonsense +1 more)
not provided
GUncertain significance
DEAF1
(Q22E +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(L21S +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GConflicting classifications of pathogenicity
DEAF1
(I256N +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GLikely pathogenic
DEAF1
(R254del +1 more)
Microsatellite
(inframe_deletion +1 more)
not provided
GUncertain significance
DEAF1
(R254S +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GPathogenic
DEAF1
(K250E +1 more)
Single nucleotide variant
(missense variant +1 more)
Intellectual disability, autosomal dominant 24
+1 more
GPathogenic/Likely pathogenic
DEAF1
(S249N +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(M1I +1 more)
Single nucleotide variant
(missense variant +2 more)
not provided
GUncertain significance
DEAF1
(E241D)
Single nucleotide variant
(5 prime UTR variant +2 more)
Inborn genetic diseases
+1 more
GUncertain significance
DEAF1
(E239G)
Single nucleotide variant
(5 prime UTR variant +2 more)
Intellectual disability-epilepsy-extrapyramidal syndrome
+1 more
GConflicting classifications of pathogenicity
DEAF1
(S236G)
Single nucleotide variant
(5 prime UTR variant +2 more)
not provided
GLikely pathogenic
DEAF1
(W234*)
Single nucleotide variant
(5 prime UTR variant +2 more)
not provided
GUncertain significance
DEAF1
(W234G)
Single nucleotide variant
(5 prime UTR variant +2 more)
not provided
GPathogenic/Likely pathogenic
DEAF1
(Q230P)
Single nucleotide variant
(5 prime UTR variant +2 more)
not provided
GUncertain significance
DEAF1
(R224Q)
Single nucleotide variant
(5 prime UTR variant +2 more)
not provided
+1 more
GConflicting classifications of pathogenicity
DEAF1
(R224W)
Single nucleotide variant
(5 prime UTR variant +2 more)
Intellectual disability, autosomal dominant 24
+1 more
GPathogenic/Likely pathogenic
DEAF1
(G223S)
Single nucleotide variant
(5 prime UTR variant +2 more)
Intellectual disability-epilepsy-extrapyramidal syndrome
+1 more
GConflicting classifications of pathogenicity
DEAF1
Single nucleotide variant
(splice donor variant)
not provided
GPathogenic
DEAF1
(G220S)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
+2 more
GConflicting classifications of pathogenicity
DEAF1
(R218T)
Single nucleotide variant
(missense variant +1 more)
not provided
GConflicting classifications of pathogenicity
DEAF1
(L214P)
Single nucleotide variant
(missense variant +1 more)
not provided
GConflicting classifications of pathogenicity
DEAF1
(G212S)
Single nucleotide variant
(missense variant +1 more)
not provided
+2 more
GPathogenic/Likely pathogenic
DEAF1
(R208W)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(C207Y)
Single nucleotide variant
(missense variant +1 more)
Intellectual disability, autosomal dominant 24
+1 more
GConflicting classifications of pathogenicity
DEAF1
(S201T)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(D195E)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(T190P)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(E186Q)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(Q185*)
Single nucleotide variant
(nonsense +1 more)
not provided
GPathogenic/Likely pathogenic
DEAF1
(P183L)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(A167T)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(G155R)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(A146V)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(G138R)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(V103M)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
Single nucleotide variant
(intron variant)
not provided
GUncertain significance
DEAF1
(A93T)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(E46*)
Single nucleotide variant
(nonsense +1 more)
not provided
GLikely pathogenic
DEAF1
(R44fs)
Deletion
(frameshift variant +1 more)
not provided
GUncertain significance
DEAF1
(P40R)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
Indel
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(A31V)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
Deletion
(inframe_deletion +1 more)
not provided
GUncertain significance
DEAF1
Deletion
(inframe_deletion +1 more)
not provided
GConflicting classifications of pathogenicity
DEAF1
(A30G)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
Deletion
(inframe_deletion +1 more)
not provided
GUncertain significance
DEAF1
Deletion
(inframe_deletion +1 more)
not provided
GUncertain significance
DEAF1
Deletion
(inframe_deletion +1 more)
not provided
GUncertain significance
CDHR5, DEAF1
+12 more
Copy number gain
See cases
GUncertain significance
TMEM80, CRACR2B
+9 more
Copy number gain
See cases
GUncertain significance
DEAF1
(D251G +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
DEAF1
(R19* +1 more)
Single nucleotide variant
not provided
GPathogenic/Likely pathogenic
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