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Items: 21

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
RRM2B
Deletion
(3 prime UTR variant)
Mitochondrial DNA depletion syndrome 8a
+4 more
GUncertain significance
RRM2B
Single nucleotide variant
(intron variant)
Rod-cone dystrophy, sensorineural deafness, and Fanconi-type renal dysfunction
+4 more
GBenign/Likely benign
RRM2B
(R252K +2 more)
Single nucleotide variant
(missense variant)
Rod-cone dystrophy, sensorineural deafness, and Fanconi-type renal dysfunction
+3 more
GUncertain significance
RRM2B
Single nucleotide variant
(intron variant)
not specified
+4 more
GBenign/Likely benign
RRM2B
(I296S +1 more)
Single nucleotide variant
(missense variant)
Mitochondrial DNA depletion syndrome 8a
+3 more
GPathogenic/Likely pathogenic
RRM2B
(I153V +2 more)
Single nucleotide variant
(missense variant)
not provided
+3 more
GUncertain significance
RRM2B
Single nucleotide variant
(intron variant)
Rod-cone dystrophy, sensorineural deafness, and Fanconi-type renal dysfunction
+3 more
GBenign/Likely benign
RRM2B
Single nucleotide variant
(synonymous variant)
Rod-cone dystrophy, sensorineural deafness, and Fanconi-type renal dysfunction
+3 more
GLikely benign
RRM2B
(N229S +2 more)
Single nucleotide variant
(missense variant)
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 5
+3 more
GUncertain significance
RRM2B
Single nucleotide variant
(splice donor variant)
not provided
+3 more
GLikely pathogenic
RRM2B
Single nucleotide variant
(intron variant)
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 5
+3 more
GLikely benign
RRM2B
(K158N +2 more)
Single nucleotide variant
(missense variant)
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 5
+3 more
GUncertain significance
RRM2B
(E157del +2 more)
Deletion
(inframe_deletion)
Mitochondrial DNA depletion syndrome 8a
+3 more
GConflicting classifications of pathogenicity
RRM2B
(Q120R +1 more)
Single nucleotide variant
(missense variant +1 more)
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 5
+3 more
GUncertain significance
RRM2B
(R112H +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+3 more
GUncertain significance
RRM2B
Single nucleotide variant
(intron variant)
Mitochondrial DNA depletion syndrome 8a
+3 more
GBenign/Likely benign
RRM2B
Single nucleotide variant
(synonymous variant +1 more)
not specified
+4 more
GBenign/Likely benign
RRM2B
(E62fs)
Deletion
(frameshift variant +1 more)
Mitochondrial DNA depletion syndrome 8a
+4 more
GUncertain significance
RRM2B
(R51Q)
Single nucleotide variant
(missense variant +1 more)
Rod-cone dystrophy, sensorineural deafness, and Fanconi-type renal dysfunction
+3 more
GUncertain significance
RRM2B
(P15L)
Single nucleotide variant
(missense variant +1 more)
not provided
+3 more
GBenign/Likely benign
LOC130000896, RRM2B
Single nucleotide variant
(5 prime UTR variant +1 more)
Mitochondrial DNA depletion syndrome 8a
+3 more
GPathogenic/Likely pathogenic
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