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Items: 60

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
NBN
(L739V +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+4 more
GUncertain significance
NBN
(T717S +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+5 more
GUncertain significance
NBN
(N716D +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+6 more
GBenign/Likely benign
NBN
(R714* +1 more)
Single nucleotide variant
(nonsense)
Aplastic anemia
+4 more
GPathogenic/Likely pathogenic
NBN
(S667P +1 more)
Single nucleotide variant
(missense variant)
Aplastic anemia
+5 more
GConflicting classifications of pathogenicity
LOC126860438, NBN
(K635* +1 more)
Single nucleotide variant
(nonsense)
Aplastic anemia
+4 more
GPathogenic/Likely pathogenic
LOC126860438, NBN
(E628K +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+6 more
GBenign/Likely benign
NBN
(M513V +1 more)
Single nucleotide variant
(missense variant)
not provided
+4 more
GUncertain significance
NBN
(E585G +1 more)
Single nucleotide variant
(missense variant)
not specified
+5 more
GConflicting classifications of pathogenicity
NBN
(Q583* +1 more)
Single nucleotide variant
(nonsense)
Aplastic anemia
+4 more
GPathogenic/Likely pathogenic
NBN
(K468fs +1 more)
Deletion
(frameshift variant)
Hereditary cancer-predisposing syndrome
+4 more
GPathogenic/Likely pathogenic
NBN
(T497A +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+6 more
GBenign/Likely benign
NBN
(P413fs +1 more)
Indel
(frameshift variant)
Microcephaly, normal intelligence and immunodeficiency
+4 more
GPathogenic/Likely pathogenic
NBN
(S486F +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GUncertain significance
NBN
Deletion
(splice donor variant)
Microcephaly, normal intelligence and immunodeficiency
+4 more
GPathogenic
NBN
(P427T +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GConflicting classifications of pathogenicity
NBN
(L421S +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+6 more
GConflicting classifications of pathogenicity
NBN
(M416T +1 more)
Single nucleotide variant
(missense variant)
Acute lymphoid leukemia
+5 more
GUncertain significance
NBN
(K408E +1 more)
Single nucleotide variant
(missense variant)
Hereditary breast ovarian cancer syndrome
+6 more
GBenign/Likely benign
NBN
(S287* +1 more)
Single nucleotide variant
(nonsense)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GPathogenic/Likely pathogenic
NBN
(P354S +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GUncertain significance
NBN
(G345V +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+4 more
GUncertain significance
NBN
(Q344* +1 more)
Single nucleotide variant
(nonsense)
Microcephaly, normal intelligence and immunodeficiency
+4 more
GPathogenic/Likely pathogenic
NBN
Single nucleotide variant
(intron variant)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GBenign/Likely benign
NBN
(Q326E +1 more)
Single nucleotide variant
(missense variant)
not specified
+5 more
GUncertain significance
NBN
(I310T +1 more)
Single nucleotide variant
(missense variant)
Aplastic anemia
+3 more
GUncertain significance
NBN
(Q286R +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GUncertain significance
NBN
(T268M +1 more)
Single nucleotide variant
(missense variant)
not specified
+5 more
GUncertain significance
NBN
(P266L +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+6 more
GBenign/Likely benign
NBN
(E259K +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+5 more
GUncertain significance
NBN
(V243L +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GUncertain significance
NBN
(K151fs)
Deletion
(frameshift variant)
Aplastic anemia
+4 more
GPathogenic
NBN
(K151Q +1 more)
Single nucleotide variant
(missense variant)
Acute lymphoid leukemia
+2 more
GUncertain significance
NBN
(I228R +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+5 more
GUncertain significance
NBN
(F222L +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+5 more
GUncertain significance
NBN
(V210F +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+5 more
GConflicting classifications of pathogenicity
NBN
(P199S +1 more)
Single nucleotide variant
(missense variant)
Aplastic anemia
+4 more
GConflicting classifications of pathogenicity
NBN
Single nucleotide variant
(synonymous variant)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GLikely benign
NBN
(V172A +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+4 more
GUncertain significance
NBN
(R169C +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+7 more
GConflicting classifications of pathogenicity
NBN
(G168E +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+4 more
GUncertain significance
NBN
Single nucleotide variant
(splice acceptor variant)
Microcephaly, normal intelligence and immunodeficiency
+4 more
GPathogenic/Likely pathogenic
NBN
(M152I +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+5 more
GConflicting classifications of pathogenicity
NBN
(T144I +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GUncertain significance
NBN
(N142S +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer
+6 more
GConflicting classifications of pathogenicity
NBN
Single nucleotide variant
(synonymous variant)
Hereditary cancer-predisposing syndrome
+5 more
GBenign/Likely benign
NBN
(D121H +1 more)
Single nucleotide variant
(missense variant)
Acute lymphoid leukemia
+3 more
GUncertain significance
NBN
(S118del +1 more)
Microsatellite
(inframe_deletion)
not provided
+4 more
GUncertain significance
NBN
(V114F +1 more)
Single nucleotide variant
(missense variant)
Aplastic anemia
+5 more
GConflicting classifications of pathogenicity
NBN
(R107fs +1 more)
Duplication
(frameshift variant)
Microcephaly, normal intelligence and immunodeficiency
+2 more
GPathogenic/Likely pathogenic
NBN
(R89* +1 more)
Single nucleotide variant
(nonsense)
Aplastic anemia
+4 more
GPathogenic/Likely pathogenic
NBN
(Y74H)
Single nucleotide variant
(5 prime UTR variant +1 more)
not provided
+5 more
GUncertain significance
NBN
(N71fs)
Insertion
(5 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
+4 more
GPathogenic/Likely pathogenic
NBN
Deletion
(5 prime UTR variant +1 more)
Acute lymphoid leukemia
+6 more
GPathogenic/Likely pathogenic
NBN
(H45Q)
Single nucleotide variant
(5 prime UTR variant +1 more)
Aplastic anemia
+2 more
GUncertain significance
NBN
(S40L)
Single nucleotide variant
(5 prime UTR variant +1 more)
Microcephaly, normal intelligence and immunodeficiency
+4 more
GUncertain significance
NBN
(V26F)
Single nucleotide variant
(5 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
NBN
Single nucleotide variant
(intron variant)
Acute lymphoid leukemia
+5 more
GBenign/Likely benign
NBN
(L4R)
Single nucleotide variant
(5 prime UTR variant +1 more)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GUncertain significance
NBN
Single nucleotide variant
(5 prime UTR variant)
Microcephaly, normal intelligence and immunodeficiency
+4 more
GBenign/Likely benign
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