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Items: 17

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
MCPH1
(K259Q +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GUncertain significance
MCPH1
(D261E +3 more)
Single nucleotide variant
(missense variant +1 more)
Microcephaly 1, primary, autosomal recessive
+2 more
GConflicting classifications of pathogenicity
MCPH1
(H396N +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+3 more
GUncertain significance
MCPH1
(Y425N +3 more)
Single nucleotide variant
(missense variant +1 more)
Microcephaly 1, primary, autosomal recessive
+1 more
GConflicting classifications of pathogenicity
MCPH1
(K450T +3 more)
Single nucleotide variant
(missense variant +1 more)
Microcephaly 1, primary, autosomal recessive
+1 more
GConflicting classifications of pathogenicity
MCPH1
(R459C +3 more)
Single nucleotide variant
(missense variant +1 more)
Microcephaly 1, primary, autosomal recessive
+1 more
GUncertain significance
MCPH1
(L542* +3 more)
Single nucleotide variant
(nonsense +1 more)
not provided
+1 more
GPathogenic/Likely pathogenic
MCPH1
(S560I +3 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
+2 more
GUncertain significance
MCPH1
Single nucleotide variant
(synonymous variant +1 more)
not provided
+2 more
GBenign/Likely benign
MCPH1
Single nucleotide variant
(splice acceptor variant +1 more)
not provided
+1 more
GConflicting classifications of pathogenicity
MCPH1
(A702V)
Single nucleotide variant
(missense variant +1 more)
Microcephaly 1, primary, autosomal recessive
+2 more
GUncertain significance
MCPH1
(R703H)
Single nucleotide variant
(missense variant +1 more)
Microcephaly 1, primary, autosomal recessive
+2 more
GUncertain significance
ANGPT2, MCPH1
(P727L)
Single nucleotide variant
(3 prime UTR variant +2 more)
not provided
+4 more
GConflicting classifications of pathogenicity
MCPH1, MCPH1-AS1
Indel
(non-coding transcript variant +1 more)
not provided
+1 more
GLikely benign
MCPH1, MCPH1-AS1
(G660R +1 more)
Single nucleotide variant
(non-coding transcript variant +1 more)
not provided
+1 more
GUncertain significance
MCPH1, MCPH1-AS1
(P799S +1 more)
Single nucleotide variant
(non-coding transcript variant +1 more)
Microcephaly 1, primary, autosomal recessive
+1 more
GConflicting classifications of pathogenicity
MCPH1, MCPH1-AS1
(P828S +2 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GBenign
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