"Database of Curated Mutations (DoCM)"[submitter] AND "FBXW7"[gene] - ClinVar - NCBI

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Items: 15

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 376427	NM_001349798.2(FBXW7):c.1973G>A (p.Arg658Gln)	FBXW7 (R658Q +2 more)	Single nucleotide variant (missense variant)	Neoplasm of uterine cervix +7 more	GLikely pathogenic
Select item 376425	NM_001349798.2(FBXW7):c.1514G>A (p.Arg505His)	FBXW7 (R505H +2 more)	Single nucleotide variant (missense variant)	not provided	GConflicting classifications of pathogenicity
Select item 376424	NM_001349798.2(FBXW7):c.1514G>T (p.Arg505Leu)	FBXW7 (R505L +2 more)	Single nucleotide variant (missense variant)	Carcinoma of esophagus +11 more	GLikely pathogenic
Select item 376426	NM_001349798.2(FBXW7):c.1513C>A (p.Arg505Ser)	FBXW7 (R505S +2 more)	Single nucleotide variant (missense variant)	Neoplasm of uterine cervix +11 more	GLikely pathogenic
Select item 376423	NM_001349798.2(FBXW7):c.1513C>G (p.Arg505Gly)	FBXW7 (R505G +2 more)	Single nucleotide variant (missense variant)	Neoplasm of uterine cervix +11 more	GLikely pathogenic
Select item 69961	NM_001349798.2(FBXW7):c.1513C>T (p.Arg505Cys)	FBXW7 (R505C +2 more)	Single nucleotide variant (missense variant)	FBXW7-related neurodevelopmental disorder	GLikely pathogenic
Select item 376421	NM_001349798.2(FBXW7):c.1436G>T (p.Arg479Leu)	FBXW7 (R479L +2 more)	Single nucleotide variant (missense variant)	Uterine carcinosarcoma +11 more	GLikely pathogenic
Select item 376420	NM_001349798.2(FBXW7):c.1436G>C (p.Arg479Pro)	FBXW7 (R479P +2 more)	Single nucleotide variant (missense variant)	Uterine carcinosarcoma +11 more	GLikely pathogenic
Select item 376419	NM_001349798.2(FBXW7):c.1436G>A (p.Arg479Gln)	FBXW7 (R479Q +2 more)	Single nucleotide variant (missense variant)	Malignant neoplasm of body of uterus +11 more	GLikely pathogenic
Select item 376422	NM_001349798.2(FBXW7):c.1435C>G (p.Arg479Gly)	FBXW7 (R479G +2 more)	Single nucleotide variant (missense variant)	Uterine carcinosarcoma +11 more	GLikely pathogenic
Select item 376417	NM_001349798.2(FBXW7):c.1394G>T (p.Arg465Leu)	FBXW7 (R465L +2 more)	Single nucleotide variant (missense variant)	Squamous cell carcinoma of the head and neck +13 more	GLikely pathogenic
Select item 376416	NM_001349798.2(FBXW7):c.1394G>C (p.Arg465Pro)	FBXW7 (R465P +2 more)	Single nucleotide variant (missense variant)	Breast neoplasm +13 more	GLikely pathogenic
Select item 376415	NM_001349798.2(FBXW7):c.1394G>A (p.Arg465His)	FBXW7 (R465H +2 more)	Single nucleotide variant (missense variant)	Carcinoma of esophagus +13 more	GLikely pathogenic
Select item 376418	NM_001349798.2(FBXW7):c.1393C>G (p.Arg465Gly)	FBXW7 (R465G +2 more)	Single nucleotide variant (missense variant)	Breast neoplasm +13 more	GLikely pathogenic
Select item 376414	NM_001349798.2(FBXW7):c.1393C>T (p.Arg465Cys)	FBXW7 (R465C +2 more)	Single nucleotide variant (missense variant)	not provided	GPathogenic