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Items: 59

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
SDHA
Single nucleotide variant
(5 prime UTR variant)
Mitochondrial complex II deficiency, nuclear type 1
+6 more
GConflicting classifications of pathogenicity
SDHA
Single nucleotide variant
(5 prime UTR variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
SDHA
(M1L)
Single nucleotide variant
(missense variant +1 more)
Paragangliomas 5
+3 more
GPathogenic/Likely pathogenic
SDHA
(M1T)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+2 more
GPathogenic/Likely pathogenic
SDHA
(G6D)
Single nucleotide variant
(missense variant)
Leigh syndrome
+6 more
GConflicting classifications of pathogenicity
SDHA
(R31*)
Single nucleotide variant
(nonsense)
Gastrointestinal stromal tumor
+9 more
GPathogenic/Likely pathogenic
SDHA
(R31Q)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+5 more
GConflicting classifications of pathogenicity
SDHA
(V37I)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+3 more
GConflicting classifications of pathogenicity
SDHA
(A45T)
Single nucleotide variant
(missense variant)
Leigh syndrome
+6 more
GConflicting classifications of pathogenicity
SDHA
(K46E)
Single nucleotide variant
(missense variant)
not specified
+4 more
GConflicting classifications of pathogenicity
SDHA
(D49G)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+4 more
GConflicting classifications of pathogenicity
SDHA
(G71fs)
Duplication
(frameshift variant)
Paragangliomas 5
GLikely pathogenic
SDHA
(T96I)
Single nucleotide variant
(missense variant)
B-lymphoblastic leukemia/lymphoma with hypodiploidy
+5 more
GUncertain significance
SDHA
Single nucleotide variant
(intron variant)
not specified
+4 more
GConflicting classifications of pathogenicity
SDHA
Single nucleotide variant
(intron variant)
Hereditary cancer-predisposing syndrome
+3 more
GConflicting classifications of pathogenicity
SDHA
Single nucleotide variant
(intron variant)
Paragangliomas 5
+2 more
GLikely benign
SDHA
(F160L +1 more)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+3 more
GConflicting classifications of pathogenicity
SDHA
Single nucleotide variant
(synonymous variant)
not specified
+3 more
GBenign/Likely benign
SDHA
Single nucleotide variant
(intron variant)
Paragangliomas 5
+2 more
GConflicting classifications of pathogenicity
SDHA
(I235T +1 more)
Single nucleotide variant
(missense variant)
Dilated cardiomyopathy 1GG
+6 more
GUncertain significance
SDHA
(I247V +1 more)
Single nucleotide variant
(missense variant)
Dilated cardiomyopathy 1GG
+5 more
GConflicting classifications of pathogenicity
SDHA
(V205fs +1 more)
Deletion
(frameshift variant)
Paragangliomas 5
+1 more
GPathogenic/Likely pathogenic
SDHA
Single nucleotide variant
(intron variant)
not specified
+1 more
GConflicting classifications of pathogenicity
SDHA
Deletion
(intron variant)
Paragangliomas 5
GUncertain significance
SDHA
(T273I +1 more)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+4 more
GConflicting classifications of pathogenicity
SDHA
(G276S +1 more)
Single nucleotide variant
(missense variant)
Mitochondrial complex II deficiency, nuclear type 1
+2 more
GUncertain significance
SDHA
(T277M +1 more)
Single nucleotide variant
(missense variant)
Dilated cardiomyopathy 1GG
+7 more
GConflicting classifications of pathogenicity
SDHA
(T281A +1 more)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+6 more
GUncertain significance
SDHA
Single nucleotide variant
(intron variant)
Paragangliomas 5
+5 more
GConflicting classifications of pathogenicity
SDHA
(C305Y +1 more)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+3 more
GUncertain significance
SDHA
(I319V +1 more)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+2 more
GUncertain significance
SDHA
(E324K +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+4 more
GUncertain significance
SDHA
(V333T +1 more)
Indel
(missense variant)
Paragangliomas 5
+2 more
GUncertain significance
SDHA
(D336Y +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
SDHA
(R352Q +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+6 more
GConflicting classifications of pathogenicity
SDHA
Single nucleotide variant
(intron variant)
not provided
+3 more
GConflicting classifications of pathogenicity
SDHA
(P399L +1 more)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+2 more
GUncertain significance
SDHA
(V425M +1 more)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+5 more
GUncertain significance
SDHA
(V425G +1 more)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+2 more
GUncertain significance
SDHA
(A449V +1 more)
Single nucleotide variant
(missense variant)
Dilated cardiomyopathy 1GG
+2 more
GUncertain significance
SDHA
(A454T +1 more)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+2 more
GUncertain significance
SDHA
(E472K +1 more)
Single nucleotide variant
(missense variant)
Dilated cardiomyopathy 1GG
+4 more
GConflicting classifications of pathogenicity
SDHA
(C475R +1 more)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+3 more
GUncertain significance
SDHA
Single nucleotide variant
(intron variant)
Paragangliomas 5
+2 more
GLikely benign
SDHA
Single nucleotide variant
(intron variant)
Mitochondrial complex II deficiency, nuclear type 1
+1 more
GConflicting classifications of pathogenicity
SDHA
Single nucleotide variant
(intron variant)
Paragangliomas 5
+2 more
GBenign/Likely benign
SDHA
(R512* +1 more)
Single nucleotide variant
(nonsense)
Mitochondrial complex II deficiency, nuclear type 1
+6 more
GPathogenic/Likely pathogenic
SDHA
(V531M +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+5 more
GUncertain significance
SDHA
(T551M +1 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+4 more
GUncertain significance
SDHA
(R554Q +1 more)
Single nucleotide variant
(missense variant +1 more)
Leigh syndrome
+6 more
GConflicting classifications of pathogenicity
SDHA
Deletion
(intron variant)
Paragangliomas 5
GLikely benign
SDHA
(A575V +1 more)
Single nucleotide variant
(missense variant +1 more)
Paragangliomas 5
+5 more
GUncertain significance
SDHA
(R585W +1 more)
Single nucleotide variant
(missense variant +1 more)
Dilated cardiomyopathy 1GG
+6 more
GConflicting classifications of pathogenicity
SDHA
(R585Q +1 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+6 more
GConflicting classifications of pathogenicity
SDHA
(E640G +2 more)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+6 more
GConflicting classifications of pathogenicity
SDHA
(V644M +2 more)
Single nucleotide variant
(missense variant)
not provided
+5 more
GUncertain significance
SDHA
(E651Q +2 more)
Single nucleotide variant
(missense variant)
Paragangliomas 5
+2 more
GUncertain significance
SDHA
(A660G +2 more)
Single nucleotide variant
(missense variant)
Leigh syndrome
+5 more
GConflicting classifications of pathogenicity
SDHA
Single nucleotide variant
(3 prime UTR variant)
not provided
+1 more
GUncertain significance
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