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Items: 43

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
MLC1
Single nucleotide variant
(stop lost +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GUncertain significance
MLC1
Single nucleotide variant
(stop lost +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GLikely pathogenic
MLC1
(L359fs +5 more)
Deletion
(frameshift variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GUncertain significance
MLC1
(R356fs +5 more)
Deletion
(frameshift variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GUncertain significance
MLC1
Single nucleotide variant
(splice donor variant)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GLikely pathogenic
MLC1
(R328H +5 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+2 more
GUncertain significance
MLC1
(Q325* +5 more)
Single nucleotide variant
(nonsense +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts
+2 more
GPathogenic/Likely pathogenic
MLC1
(T320K +5 more)
Single nucleotide variant
(missense variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
+2 more
GPathogenic/Likely pathogenic
MLC1
Microsatellite
(inframe_insertion +1 more)
not provided
+2 more
GUncertain significance
MLC1
Microsatellite
(inframe_insertion +1 more)
not provided
+1 more
GUncertain significance
MLC1
(L308Q +5 more)
Single nucleotide variant
(missense variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GUncertain significance
MLC1
(Y301* +5 more)
Single nucleotide variant
(nonsense +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GLikely pathogenic
MLC1
Single nucleotide variant
(splice acceptor variant)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GLikely pathogenic
MLC1
(S280L +5 more)
Single nucleotide variant
(missense variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GUncertain significance
MLC1
(A275D +5 more)
Single nucleotide variant
(missense variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
+1 more
GPathogenic/Likely pathogenic
MLC1
(T274I +5 more)
Single nucleotide variant
(missense variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GUncertain significance
MLC1
Duplication
(splice donor variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GUncertain significance
MLC1
Single nucleotide variant
(intron variant)
Megalencephalic leukoencephalopathy with subcortical cysts 1
+2 more
GConflicting classifications of pathogenicity
MLC1
Single nucleotide variant
(splice donor variant)
not provided
+1 more
GPathogenic/Likely pathogenic
MLC1
(N218K +4 more)
Single nucleotide variant
(missense variant +1 more)
not specified
+2 more
GBenign/Likely benign
MLC1
(G212R +4 more)
Single nucleotide variant
(missense variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts
+1 more
GLikely pathogenic
MLC1
(G212R +4 more)
Single nucleotide variant
(missense variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
+2 more
GPathogenic/Likely pathogenic
MLC1
(V210I +4 more)
Single nucleotide variant
(missense variant +1 more)
not specified
+2 more
GConflicting classifications of pathogenicity
MLC1
(A209fs +4 more)
Deletion
(frameshift variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GLikely pathogenic
MLC1
Single nucleotide variant
(splice donor variant)
not provided
+1 more
GPathogenic/Likely pathogenic
MLC1
(L150fs +4 more)
Deletion
(frameshift variant +1 more)
not provided
+1 more
GPathogenic
MLC1
(L150fs +4 more)
Deletion
(frameshift variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GPathogenic
MLC1
Duplication
(splice donor variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GLikely pathogenic
MLC1
(N110fs +2 more)
Deletion
(frameshift variant +2 more)
not provided
+1 more
GPathogenic/Likely pathogenic
MLC1
Single nucleotide variant
(splice donor variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GLikely pathogenic
MLC1
Single nucleotide variant
(splice donor variant +1 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
+1 more
GLikely pathogenic
MLC1
(P92S +2 more)
Single nucleotide variant
(missense variant +2 more)
Megalencephalic leukoencephalopathy with subcortical cysts
+2 more
GPathogenic/Likely pathogenic
MLC1
(I91fs +2 more)
Deletion
(frameshift variant +2 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GLikely pathogenic
LOC125446261, MLC1
(E79K)
Single nucleotide variant
(missense variant +3 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
+1 more
GUncertain significance
MLC1
Single nucleotide variant
(intron variant)
Megalencephalic leukoencephalopathy with subcortical cysts 1
+1 more
GBenign/Likely benign
MLC1
(C46fs)
Deletion
(frameshift variant +2 more)
not provided
+1 more
GPathogenic/Likely pathogenic
MLC1
(A32V)
Single nucleotide variant
(missense variant +2 more)
not provided
+1 more
GConflicting classifications of pathogenicity
MLC1
(Y28*)
Duplication
(nonsense +2 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GLikely pathogenic
MLC1
(P25R)
Single nucleotide variant
(missense variant +2 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GUncertain significance
MLC1
(Q23*)
Single nucleotide variant
(nonsense +2 more)
not provided
+1 more
GPathogenic/Likely pathogenic
MLC1
(R22Q)
Single nucleotide variant
(missense variant +2 more)
not specified
+2 more
GUncertain significance
MLC1
(M15fs)
Deletion
(frameshift variant +2 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GLikely pathogenic
MLC1
Single nucleotide variant
(5 prime UTR variant +3 more)
Megalencephalic leukoencephalopathy with subcortical cysts 1
GUncertain significance
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