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Items: 51

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
SDHC
(A2T)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
SDHC
(A2G)
Single nucleotide variant
(missense variant)
Paragangliomas 3
+2 more
GUncertain significance
SDHC
(A3T)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+4 more
GUncertain significance
SDHC
(A3S)
Single nucleotide variant
(missense variant)
not provided
+4 more
GUncertain significance
SDHC
(A3V)
Single nucleotide variant
(missense variant)
Paragangliomas 3
+5 more
GUncertain significance
SDHC
(L4P)
Single nucleotide variant
(missense variant)
not provided
+4 more
GUncertain significance
SDHC
(L5M)
Single nucleotide variant
(missense variant)
Gastrointestinal stromal tumor
+3 more
GUncertain significance
SDHC
(L5F)
Single nucleotide variant
(missense variant)
not provided
+4 more
GUncertain significance
SDHC
Single nucleotide variant
(5 prime UTR variant +1 more)
Gastrointestinal stromal tumor
+2 more
GUncertain significance
SDHC
(R11H)
Single nucleotide variant
(missense variant +3 more)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
SDHC
(R11L)
Single nucleotide variant
(missense variant +3 more)
Hereditary cancer-predisposing syndrome
+4 more
GUncertain significance
SDHC
(L14F)
Single nucleotide variant
(missense variant +3 more)
not specified
+5 more
GUncertain significance
SDHC
(R15*)
Single nucleotide variant
(nonsense +3 more)
Hereditary pheochromocytoma-paraganglioma
+4 more
GPathogenic
SDHC
(R15Q)
Single nucleotide variant
(missense variant +3 more)
Paragangliomas 3
+3 more
GUncertain significance
SDHC
(A16V)
Single nucleotide variant
(missense variant +3 more)
Paragangliomas 3
+1 more
GUncertain significance
SDHC
(L22F)
Single nucleotide variant
(missense variant +3 more)
not provided
+3 more
GUncertain significance
SDHC
(C23Y)
Single nucleotide variant
(missense variant +3 more)
Gastrointestinal stromal tumor
+2 more
GUncertain significance
SDHC
(T33M +1 more)
Single nucleotide variant
(missense variant +3 more)
Gastrointestinal stromal tumor
+5 more
GUncertain significance
SDHC
(E20G +2 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
SDHC
(E39A +2 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
SDHC
(R40W +2 more)
Single nucleotide variant
(missense variant +2 more)
Gastrointestinal stromal tumor
+4 more
GUncertain significance
SDHC
(R40Q +2 more)
Single nucleotide variant
(missense variant +2 more)
Paragangliomas 3
+3 more
GUncertain significance
SDHC
(N49D +2 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary pheochromocytoma-paraganglioma
+2 more
GUncertain significance
SDHC
(N49T +2 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
SDHC
(N49S +2 more)
Single nucleotide variant
(missense variant +2 more)
Paragangliomas 3
+1 more
GUncertain significance
SDHC
(R50C +2 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+4 more
GConflicting classifications of pathogenicity
SDHC
Single nucleotide variant
(splice donor variant +1 more)
Gastrointestinal stromal tumor
+1 more
GLikely pathogenic
SDHC
Single nucleotide variant
(intron variant)
Gastrointestinal stromal tumor
+1 more
GUncertain significance
SDHC
(A66V +5 more)
Single nucleotide variant
(missense variant)
Paragangliomas 3
+2 more
GUncertain significance
SDHC
(R72H +5 more)
Single nucleotide variant
(missense variant)
Hereditary pheochromocytoma-paraganglioma
+4 more
GConflicting classifications of pathogenicity
SDHC
(V82F +7 more)
Single nucleotide variant
(missense variant +2 more)
Gastrointestinal stromal tumor
+2 more
GUncertain significance
SDHC
(G126R +7 more)
Single nucleotide variant
(missense variant +2 more)
Gastrointestinal stromal tumor
GUncertain significance
SDHC
(S88L +7 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+3 more
GConflicting classifications of pathogenicity
SDHC
(L37V +7 more)
Single nucleotide variant
(missense variant +2 more)
Gastrointestinal stromal tumor
+2 more
GUncertain significance
SDHC
(S98A +7 more)
Single nucleotide variant
(missense variant +2 more)
Gastrointestinal stromal tumor
+4 more
GUncertain significance
SDHC
(Y99H +7 more)
Single nucleotide variant
(missense variant +2 more)
Paragangliomas 3
+4 more
GConflicting classifications of pathogenicity
SDHC
(K104E +7 more)
Single nucleotide variant
(missense variant +2 more)
Gastrointestinal stromal tumor
+1 more
GUncertain significance
SDHC
(L120F +7 more)
Single nucleotide variant
(missense variant +2 more)
Gastrointestinal stromal tumor
+2 more
GUncertain significance
SDHC
(P89S +7 more)
Single nucleotide variant
(missense variant +2 more)
not provided
+4 more
GUncertain significance
SDHC
(Y126C +7 more)
Single nucleotide variant
(missense variant +2 more)
Gastrointestinal stromal tumor
+4 more
GPathogenic/Likely pathogenic
SDHC
(H127R +7 more)
Single nucleotide variant
(missense variant +2 more)
not provided
+4 more
GPathogenic/Likely pathogenic
SDHC
(W129* +7 more)
Single nucleotide variant
(nonsense +2 more)
Gastrointestinal stromal tumor
+3 more
GPathogenic/Likely pathogenic
SDHC
(R133* +7 more)
Single nucleotide variant
(nonsense +2 more)
Hereditary cancer-predisposing syndrome
+5 more
GPathogenic
SDHC
(R133Q +7 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary pheochromocytoma-paraganglioma
+3 more
GUncertain significance
SDHC
(L135M +7 more)
Single nucleotide variant
(missense variant +2 more)
Gastrointestinal stromal tumor
+1 more
GUncertain significance
SDHC
(K141R +7 more)
Single nucleotide variant
(synonymous variant +2 more)
Hereditary pheochromocytoma-paraganglioma
+4 more
GUncertain significance
SDHC
(K144T +10 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
SDHC
(K144N +10 more)
Single nucleotide variant
(missense variant)
Hereditary pheochromocytoma-paraganglioma
+3 more
GUncertain significance
SDHC
(P146T +10 more)
Single nucleotide variant
(missense variant)
Gastrointestinal stromal tumor
+3 more
GUncertain significance
SDHC
(A146V +7 more)
Single nucleotide variant
(non-coding transcript variant +2 more)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
ADCY10, ALDH9A1
+137 more
Copy number loss
not provided
GPathogenic
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