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Items: 21

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
NPC1
(N1156S)
Single nucleotide variant
(missense variant)
Niemann-Pick disease, type C1
+2 more
GPathogenic
NPC1
(I1061T)
Single nucleotide variant
(missense variant)
Sphingomyelin/cholesterol lipidosis
+4 more
GPathogenic
NPC1
(P1007A)
Single nucleotide variant
(missense variant)
Cataplexy
+9 more
GPathogenic
NPC1
(S1004L)
Single nucleotide variant
(missense variant)
Niemann-Pick disease, type C1
+2 more
GConflicting classifications of pathogenicity
NPC1
(G992W)
Single nucleotide variant
(missense variant)
not provided
+1 more
GPathogenic/Likely pathogenic
NPC1
(P981L)
Single nucleotide variant
(missense variant)
Niemann-Pick disease, type C1
+1 more
GUncertain significance
NPC1
(R978C)
Single nucleotide variant
(missense variant)
not provided
+2 more
GPathogenic/Likely pathogenic
NPC1
Single nucleotide variant
(synonymous variant)
Niemann-Pick disease, type C1
+2 more
GConflicting classifications of pathogenicity
NPC1
(V950M)
Single nucleotide variant
(missense variant)
not provided
+1 more
GPathogenic/Likely pathogenic
NPC1
(Q921*)
Single nucleotide variant
(nonsense)
Niemann-Pick disease, type C1
+3 more
GPathogenic/Likely pathogenic
NPC1
(N916S)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
NPC1
(D874V)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+3 more
GPathogenic/Likely pathogenic
NPC1
(V810F)
Single nucleotide variant
(missense variant)
Niemann-Pick disease, type C1
+1 more
GConflicting classifications of pathogenicity
NPC1
(L766*)
Single nucleotide variant
(nonsense)
Niemann-Pick disease, type C1
GPathogenic
NPC1
(C479Y)
Single nucleotide variant
(missense variant)
not provided
+2 more
GConflicting classifications of pathogenicity
NPC1
(E451K)
Single nucleotide variant
(missense variant)
Niemann-Pick disease, type C
+1 more
GConflicting classifications of pathogenicity
NPC1
(L408P)
Single nucleotide variant
(missense variant)
not provided
+2 more
GUncertain significance
NPC1
(R404Q)
Single nucleotide variant
(missense variant)
Niemann-Pick disease, type C1
+2 more
GPathogenic
NPC1
(L280fs)
Deletion
(frameshift variant)
Niemann-Pick disease, type C1
GLikely pathogenic
NPC1
(M156T)
Single nucleotide variant
(missense variant)
Niemann-Pick disease, type C1
+1 more
GUncertain significance
NPC1
(T137M)
Single nucleotide variant
(missense variant)
Niemann-Pick disease, type C
+2 more
GConflicting classifications of pathogenicity
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