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Items: 15

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
LOC126860438, NBN
Microsatellite
(splice donor variant)
Microcephaly, normal intelligence and immunodeficiency
+2 more
GConflicting classifications of pathogenicity
LOC126860438, NBN
(S638Y +1 more)
Single nucleotide variant
(missense variant)
not specified
+4 more
GUncertain significance
LOC126860438, NBN
(K635* +1 more)
Single nucleotide variant
(nonsense)
Aplastic anemia
+4 more
GPathogenic/Likely pathogenic
LOC126860438, NBN
(W550R +1 more)
Single nucleotide variant
(missense variant)
Microcephaly, normal intelligence and immunodeficiency
+3 more
GUncertain significance
LOC126860438, NBN
(S548* +1 more)
Single nucleotide variant
(nonsense)
Aplastic anemia
GLikely pathogenic
LOC126860438, NBN
(S548* +1 more)
Single nucleotide variant
(nonsense)
Hereditary cancer-predisposing syndrome
+2 more
GPathogenic/Likely pathogenic
LOC126860438, NBN
(E628fs +1 more)
Deletion
(frameshift variant)
not provided
+3 more
GPathogenic/Likely pathogenic
LOC126860438, NBN
(E543fs +1 more)
Duplication
(frameshift variant)
Aplastic anemia
GLikely pathogenic
LOC126860438, NBN
(R624H +1 more)
Single nucleotide variant
(missense variant)
Aplastic anemia
+3 more
GUncertain significance
LOC126860438, NBN
(R542G +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GUncertain significance
LOC126860438, NBN
(R624C +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GConflicting classifications of pathogenicity
LOC126860438, NBN
(E535D +1 more)
Single nucleotide variant
(missense variant)
Aplastic anemia
+2 more
GUncertain significance
LOC126860438, NBN
(E617K +1 more)
Single nucleotide variant
(missense variant)
not specified
+3 more
GUncertain significance
LOC126860438, NBN
(E617fs +1 more)
Deletion
(frameshift variant)
Aplastic anemia
+2 more
GPathogenic/Likely pathogenic
LOC126860438, NBN
Single nucleotide variant
(splice acceptor variant)
Aplastic anemia
+2 more
GConflicting classifications of pathogenicity
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