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Items: 22

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
FBN1
(K2848T)
Single nucleotide variant
(missense variant)
Marfan syndrome
+3 more
GUncertain significance
FBN1
(R2726W)
Single nucleotide variant
(missense variant)
Familial thoracic aortic aneurysm and aortic dissection
+8 more
GConflicting classifications of pathogenicity
FBN1
(G2669R)
Single nucleotide variant
(missense variant)
Stiff skin syndrome
GLikely pathogenic
FBN1
(C2448Y)
Single nucleotide variant
(missense variant)
Marfan syndrome
GPathogenic
FBN1
(E2447K)
Single nucleotide variant
(missense variant)
Connective tissue disorder
+3 more
GPathogenic/Likely pathogenic
FBN1
(R2414*)
Single nucleotide variant
(nonsense)
Familial thoracic aortic aneurysm and aortic dissection
+1 more
GPathogenic
FBN1
(C2230Y)
Single nucleotide variant
(missense variant)
Marfan syndrome
+2 more
GLikely pathogenic
FBN1
(C2111Y)
Single nucleotide variant
(missense variant)
Marfan syndrome
+2 more
GPathogenic/Likely pathogenic
FBN1
Single nucleotide variant
(synonymous variant)
Familial thoracic aortic aneurysm and aortic dissection
+1 more
GConflicting classifications of pathogenicity
FBN1
Single nucleotide variant
(intron variant)
Familial thoracic aortic aneurysm and aortic dissection
+3 more
GConflicting classifications of pathogenicity
FBN1
(Y1962C)
Single nucleotide variant
(missense variant)
Marfan syndrome
GLikely pathogenic
FBN1
(C1748fs)
Microsatellite
(frameshift variant)
Marfan syndrome
+1 more
GPathogenic
FBN1
(R1596*)
Single nucleotide variant
(nonsense)
Marfan syndrome
+9 more
GPathogenic
FBN1
(G1353R)
Single nucleotide variant
(missense variant)
not specified
+9 more
GConflicting classifications of pathogenicity
FBN1
(R1170H)
Single nucleotide variant
(missense variant)
Marfan syndrome
GBenign
FBN1
(D1155N)
Single nucleotide variant
(missense variant)
Familial thoracic aortic aneurysm and aortic dissection
+4 more
GPathogenic/Likely pathogenic
FBN1
(P1036R)
Single nucleotide variant
(missense variant)
Marfan syndrome
GUncertain significance
FBN1
(R954L)
Single nucleotide variant
(missense variant)
Familial thoracic aortic aneurysm and aortic dissection
+1 more
GConflicting classifications of pathogenicity
FBN1
(S438C)
Single nucleotide variant
(missense variant)
Familial thoracic aortic aneurysm and aortic dissection
+2 more
GUncertain significance
FBN1, LOC113939944
(R332C)
Single nucleotide variant
(missense variant)
Familial thoracic aortic aneurysm and aortic dissection
+4 more
GConflicting classifications of pathogenicity
FBN1
(R232H)
Single nucleotide variant
(missense variant)
Stiff skin syndrome
GUncertain significance
FBN1
(M223I)
Single nucleotide variant
(missense variant)
not specified
+2 more
GUncertain significance
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