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Items: 66

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
TOP3A
(S865L +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GConflicting classifications of pathogenicity
TOP3A
(A941T +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
TOP3A
(P925L +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
TOP3A
(V904I +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(G795D +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GConflicting classifications of pathogenicity
TOP3A
(L776V +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(P866L +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
TOP3A
(N844S +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GConflicting classifications of pathogenicity
TOP3A
(R833Q +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(R738W +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(R736Q +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GConflicting classifications of pathogenicity
TOP3A
(R730C +1 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GUncertain significance
TOP3A
(G721S +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(N714S +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(T708M +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
TOP3A
(S778T +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(R670C +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
TOP3A
(P662L +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+2 more
GConflicting classifications of pathogenicity
TOP3A
(G644V +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
TOP3A
(R627H +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
TOP3A
(G674R +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(T574I +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GConflicting classifications of pathogenicity
TOP3A
(C661Y +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
TOP3A
(E550D +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(A642V +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
TOP3A
(G636R +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(A535G +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(A535D +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(V509A +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(E578A +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
TOP3A
(M575V +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GConflicting classifications of pathogenicity
TOP3A
(Y572C +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(L568I +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(H443Y +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(L526F +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(D427N +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
TOP3A
(V505M +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(S487R +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(G451R +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(C445S +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(C349S +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(P415R +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(N311K +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(I265L +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(R246K +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
TOP3A
(R243* +1 more)
Single nucleotide variant
(nonsense)
Inborn genetic diseases
+1 more
GPathogenic
TOP3A
(S316T +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(R315T +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(C296S +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(V186I +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(G184V +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
TOP3A
(R92K +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(N170S +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GLikely benign
TOP3A
(I61V +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(E154K +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
TOP3A
(A47V +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(R43H +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(E22G +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TOP3A
(S90A)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
TOP3A
(K69N)
Single nucleotide variant
(5 prime UTR variant +1 more)
Inborn genetic diseases
+1 more
GUncertain significance
TOP3A
(M58I)
Single nucleotide variant
(5 prime UTR variant +1 more)
Inborn genetic diseases
GUncertain significance
LOC130060427, TOP3A
(A50V)
Single nucleotide variant
(5 prime UTR variant +1 more)
Inborn genetic diseases
GUncertain significance
LOC130060427, TOP3A
(A45V)
Single nucleotide variant
(5 prime UTR variant +1 more)
not provided
+1 more
GConflicting classifications of pathogenicity
LOC130060427, TOP3A
(V36L)
Single nucleotide variant
(5 prime UTR variant +1 more)
Inborn genetic diseases
GUncertain significance
LOC130060427, TOP3A
(V5I)
Single nucleotide variant
(5 prime UTR variant +1 more)
Inborn genetic diseases
GUncertain significance
LOC130060427, TOP3A
(P4S)
Single nucleotide variant
(5 prime UTR variant +1 more)
Inborn genetic diseases
GUncertain significance
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