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Items: 65

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
SPTLC1
(R460C)
Single nucleotide variant
(missense variant +1 more)
not specified
+2 more
GBenign/Likely benign
SPTLC1
(A468S +3 more)
Single nucleotide variant
(missense variant)
not provided
+3 more
GConflicting classifications of pathogenicity
SPTLC1
(S462Y +2 more)
Single nucleotide variant
(synonymous variant +1 more)
not provided
+3 more
GUncertain significance
SPTLC1
(V292M +2 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
SPTLC1
(L317F +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
SPTLC1
(C438R +2 more)
Single nucleotide variant
(missense variant)
Hereditary sensory and autonomic neuropathy type 1
+1 more
GUncertain significance
SPTLC1
(E314del +2 more)
Microsatellite
(inframe_deletion)
Hereditary sensory and autonomic neuropathy type 1
+2 more
GUncertain significance
SPTLC1
(E433* +2 more)
Single nucleotide variant
(nonsense)
not specified
+1 more
GUncertain significance
SPTLC1
(M298V +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
SPTLC1
Single nucleotide variant
(intron variant)
Inborn genetic diseases
GUncertain significance
SPTLC1
Single nucleotide variant
(synonymous variant)
Neuropathy, hereditary sensory and autonomic, type 1A
+3 more
GLikely benign
SPTLC1
(R405H +2 more)
Single nucleotide variant
(missense variant)
Neuropathy, hereditary sensory and autonomic, type 1A
+2 more
GUncertain significance
SPTLC1
(R405C +2 more)
Single nucleotide variant
(missense variant)
Hereditary sensory and autonomic neuropathy type 1
+2 more
GUncertain significance
SPTLC1
(T247A +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
SPTLC1
(L235F +2 more)
Single nucleotide variant
(missense variant)
Charcot-Marie-Tooth disease
+2 more
GConflicting classifications of pathogenicity
SPTLC1
(G232E +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+3 more
GUncertain significance
SPTLC1
(G387A +2 more)
Single nucleotide variant
(missense variant)
Neuropathy, hereditary sensory and autonomic, type 1A
+4 more
GBenign/Likely benign
SPTLC1
Single nucleotide variant
(intron variant)
Hereditary sensory and autonomic neuropathy type 1
+2 more
GLikely benign
SPTLC1
(K245R +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
SPTLC1
(G206R +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
SPTLC1
(N232S +2 more)
Single nucleotide variant
(missense variant)
Hereditary sensory and autonomic neuropathy type 1
+1 more
GLikely benign
SPTLC1
Single nucleotide variant
(synonymous variant)
Hereditary sensory and autonomic neuropathy type 1
+1 more
GLikely benign
SPTLC1
(S340L +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+3 more
GUncertain significance
SPTLC1
(S338T +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GConflicting classifications of pathogenicity
SPTLC1
Single nucleotide variant
(intron variant)
not provided
+4 more
GBenign/Likely benign
SPTLC1
Single nucleotide variant
(synonymous variant)
Hereditary sensory and autonomic neuropathy type 1
+2 more
GLikely benign
SPTLC1
(M307V +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
SPTLC1
Single nucleotide variant
(intron variant)
Hereditary sensory and autonomic neuropathy type 1
+2 more
GUncertain significance
SPTLC1
(Y293C +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
SPTLC1
(I116M +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
SPTLC1
(I116V +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
SPTLC1
Single nucleotide variant
(synonymous variant)
Hereditary sensory and autonomic neuropathy type 1
+4 more
GLikely benign
SPTLC1
(K262E +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+2 more
GConflicting classifications of pathogenicity
SPTLC1
(I132V +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
SPTLC1
(I99fs +2 more)
Deletion
(frameshift variant)
Inborn genetic diseases
GUncertain significance
SPTLC1
(Y248C +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
SPTLC1
(R85H +2 more)
Single nucleotide variant
(missense variant)
Hereditary sensory and autonomic neuropathy type 1
+1 more
GUncertain significance
SPTLC1
(R118C +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
SPTLC1
(R111H +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
SPTLC1
Indel
(intron variant)
Inborn genetic diseases
GUncertain significance
SPTLC1
(K108T +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
SPTLC1
(L221I +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+2 more
GUncertain significance
SPTLC1
Single nucleotide variant
(synonymous variant)
Hereditary sensory and autonomic neuropathy type 1
+1 more
GLikely benign
SPTLC1
Single nucleotide variant
(synonymous variant)
Hereditary sensory and autonomic neuropathy type 1
+2 more
GLikely benign
SPTLC1
Single nucleotide variant
(synonymous variant)
Inborn genetic diseases
+2 more
GBenign/Likely benign
SPTLC1
(A161T +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
SPTLC1
(V144D +1 more)
Single nucleotide variant
(missense variant +1 more)
Charcot-Marie-Tooth disease
+4 more
GPathogenic/Likely pathogenic
SPTLC1
Single nucleotide variant
(intron variant)
Inborn genetic diseases
+1 more
GBenign/Likely benign
SPTLC1
(C133Y)
Single nucleotide variant
(missense variant +1 more)
Hereditary sensory and autonomic neuropathy type 1
+1 more
GPathogenic
SPTLC1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary sensory and autonomic neuropathy type 1
+1 more
GLikely benign
SPTLC1
Single nucleotide variant
(synonymous variant +1 more)
Neuropathy, hereditary sensory and autonomic, type 1A
+4 more
GBenign/Likely benign
SPTLC1
(A123T)
Single nucleotide variant
(missense variant +1 more)
Hereditary sensory and autonomic neuropathy type 1
+2 more
GConflicting classifications of pathogenicity
SPTLC1
(G110A)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
SPTLC1
(T93S)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
SPTLC1
(S90N)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
+1 more
GUncertain significance
SPTLC1
Single nucleotide variant
(synonymous variant +1 more)
not provided
+4 more
GLikely benign
SPTLC1
Single nucleotide variant
(synonymous variant +1 more)
not specified
+2 more
GLikely benign
SPTLC1
(K75N)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
SPTLC1
(V70F)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
+2 more
GConflicting classifications of pathogenicity
SPTLC1
(F40L)
Single nucleotide variant
(missense variant +1 more)
Hereditary sensory and autonomic neuropathy type 1
+4 more
GConflicting classifications of pathogenicity
SPTLC1
(V11G)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
SPTLC1
(L10V)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
SPTLC1
(T5R)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
SPTLC1
(A4T)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
SPTLC1
(M1V)
Single nucleotide variant
(missense variant +2 more)
Inborn genetic diseases
+1 more
GUncertain significance
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