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Items: 24

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
SYNGAP1
(T153fs)
Deletion
(frameshift variant)
Intellectual disability, autosomal dominant 5
Gnot provided
WDR45
(K225fs +1 more)
Deletion
(frameshift variant)
Neurodegeneration with brain iron accumulation 5
Gnot provided
GABRG2
(T176N +8 more)
Single nucleotide variant
(missense variant +1 more)
Developmental and epileptic encephalopathy, 74
Gnot provided
LOC102724058, SCN1A
(T1541fs +5 more)
Deletion
(frameshift variant +1 more)
Severe myoclonic epilepsy in infancy
Gnot provided
GRIN2A
Single nucleotide variant
(splice acceptor variant)
Landau-Kleffner syndrome
Gnot provided
PCDH19
(Q290fs)
Duplication
(frameshift variant)
Developmental and epileptic encephalopathy, 9
Gnot provided
LOC102724058, SCN1A
(G1246V +5 more)
Single nucleotide variant
(missense variant +1 more)
Developmental and epileptic encephalopathy 6B
Gnot provided
SLC35A2
(W191* +3 more)
Single nucleotide variant
(nonsense +1 more)
SLC35A2-congenital disorder of glycosylation
Gnot provided
HECW2
(D450N +1 more)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder with hypotonia, seizures, and absent language
Gnot provided
SZT2
(R482C)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
SCN1A
(D807E +5 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
PCDH19
(T404I)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 9
GPathogenic
SCN1A
(R117S +5 more)
Single nucleotide variant
(missense variant +1 more)
Severe myoclonic epilepsy in infancy
+1 more
GPathogenic/Likely pathogenic
KCNA2
(P407R)
Single nucleotide variant
(missense variant +1 more)
Developmental and epileptic encephalopathy, 32
GPathogenic
KCNQ3
(P387R +1 more)
Single nucleotide variant
(missense variant)
Benign neonatal seizures
+1 more
GUncertain significance
TSC1
(L93P)
Single nucleotide variant
(missense variant +2 more)
Tuberous sclerosis 1
GUncertain significance
KCNQ3
(R244C +1 more)
Single nucleotide variant
(missense variant)
Benign neonatal seizures
GPathogenic
SZT2
(R1514W +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
TBCE
Single nucleotide variant
(splice donor variant)
not provided
+3 more
GConflicting classifications of pathogenicity
TPP1
(Q278P)
Single nucleotide variant
(missense variant)
Neuronal ceroid lipofuscinosis 2
GUncertain significance
WWOX
(V316L +1 more)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 1
+1 more
GUncertain significance
SLC6A1
(G307R +2 more)
Single nucleotide variant
(missense variant)
not provided
+3 more
GPathogenic/Likely pathogenic
CHD2
(Q1641*)
Single nucleotide variant
(nonsense)
Developmental and epileptic encephalopathy 94
GPathogenic
STXBP1
Single nucleotide variant
(splice donor variant)
Developmental and epileptic encephalopathy, 4
GPathogenic
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