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Items: 21

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
KIF5A
(E323fs +1 more)
Duplication
(frameshift variant)
Hereditary spastic paraplegia 10
GPathogenic
SPAST
Single nucleotide variant
(splice acceptor variant)
Hereditary spastic paraplegia 4
GPathogenic
SPAST
Deletion
(splice acceptor variant)
Hereditary spastic paraplegia 4
GLikely pathogenic
SPAST
Single nucleotide variant
(splice acceptor variant)
Hereditary spastic paraplegia 4
GPathogenic
SPAST
Single nucleotide variant
(intron variant)
Hereditary spastic paraplegia 4
GPathogenic
MTMR2
(C155R +1 more)
Single nucleotide variant
(missense variant)
Charcot-Marie-Tooth disease type 4B1
GLikely pathogenic
PMP22
Duplication
Charcot-Marie-Tooth disease, type IA
GPathogenic
SCP2
(P215S +3 more)
Single nucleotide variant
(missense variant)
Sterol carrier protein 2 deficiency
GUncertain significance
DYNC1H1
(E2248G)
Single nucleotide variant
(missense variant)
Charcot-Marie-Tooth disease axonal type 2O
GUncertain significance
DYNC1H1
(V3307L)
Single nucleotide variant
(missense variant)
Charcot-Marie-Tooth disease axonal type 2O
GUncertain significance
MED25
(G317C)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
GDAP1
(K47fs)
Deletion
(5 prime UTR variant +3 more)
Charcot-Marie-Tooth disease axonal type 2K
GPathogenic
KIF5A
(L868del +1 more)
Deletion
(inframe_deletion)
Hereditary spastic paraplegia 10
GLikely pathogenic
HSPB1
(Q190H)
Single nucleotide variant
(missense variant)
Charcot-Marie-Tooth disease axonal type 2F
GConflicting classifications of pathogenicity
TUBB4A
(P125S +3 more)
Single nucleotide variant
(missense variant)
Torsion dystonia 4
GBenign
PNKP
(Q50E)
Single nucleotide variant
(missense variant)
not provided
GPathogenic
ATP7A
(S688N)
Single nucleotide variant
(missense variant)
Menkes kinky-hair syndrome
GBenign
POLR3A
(N775K)
Single nucleotide variant
(missense variant)
Leukoencephalopathy-ataxia-hypodontia-hypomyelination syndrome
GPathogenic
MFN2
(Q754fs)
Duplication
(frameshift variant)
Charcot-Marie-Tooth disease type 2
+2 more
GConflicting classifications of pathogenicity
SPAST
Single nucleotide variant
(splice donor variant)
Hereditary spastic paraplegia 4
+4 more
GPathogenic/Likely pathogenic
TSC2
(R1483T +9 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GBenign/Likely benign
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