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Items: 1 to 100 of 117

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
BRCA2
(R3384G)
Single nucleotide variant
(missense variant)
Hereditary breast ovarian cancer syndrome
+3 more
GUncertain significance
BRCA2
(R3005T)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
BRCA2
(R3007K)
Single nucleotide variant
(missense variant)
Breast neoplasm
GUncertain significance
BRCA2
(T2834A)
Single nucleotide variant
(missense variant)
Breast neoplasm
+1 more
GUncertain significance
BRCA2
(K2777E)
Single nucleotide variant
(missense variant)
Hereditary breast ovarian cancer syndrome
+1 more
GUncertain significance
BRCA2
(L2656P)
Single nucleotide variant
(missense variant)
Breast neoplasm
GUncertain significance
BRCA2
(E2558Q)
Single nucleotide variant
(missense variant)
Breast neoplasm
GUncertain significance
BRCA2
Single nucleotide variant
(synonymous variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GLikely benign
BRCA2
Single nucleotide variant
(synonymous variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GLikely benign
BRCA2
(I1516M)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+2 more
GConflicting classifications of pathogenicity
BRCA2
(C1159G)
Single nucleotide variant
(missense variant)
Hereditary breast ovarian cancer syndrome
+2 more
GConflicting classifications of pathogenicity
BRCA2
Single nucleotide variant
(synonymous variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GLikely benign
BRCA2
(V2079L)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GConflicting classifications of pathogenicity
BRCA2
(L1829F)
Single nucleotide variant
(missense variant)
not specified
+6 more
GConflicting classifications of pathogenicity
BRCA2
(I2086V)
Single nucleotide variant
(missense variant)
Breast neoplasm
+1 more
GConflicting classifications of pathogenicity
BRCA2
(K1018Q)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GConflicting classifications of pathogenicity
BRCA2
(F2200L)
Single nucleotide variant
(missense variant)
Breast neoplasm
+1 more
GConflicting classifications of pathogenicity
BRCA2
(Q1782R)
Single nucleotide variant
(missense variant)
Breast neoplasm
+1 more
GConflicting classifications of pathogenicity
BRCA2
(E1158G)
Single nucleotide variant
(missense variant)
Breast neoplasm
+1 more
GConflicting classifications of pathogenicity
BRCA2
(S504C)
Single nucleotide variant
(missense variant)
not provided
+4 more
GConflicting classifications of pathogenicity
BRCA2
(D596N)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GConflicting classifications of pathogenicity
BRCA2
(I488V)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+3 more
GConflicting classifications of pathogenicity
BRCA2
(K531E)
Single nucleotide variant
(missense variant)
Hereditary breast ovarian cancer syndrome
+2 more
GConflicting classifications of pathogenicity
BRCA2
(N404S)
Single nucleotide variant
(missense variant)
BRCA2-related disorder
+5 more
GConflicting classifications of pathogenicity
BRCA2
(T152A)
Single nucleotide variant
(missense variant)
Familial cancer of breast
+5 more
GConflicting classifications of pathogenicity
BRCA2
(Q154R)
Single nucleotide variant
(missense variant)
Hereditary breast ovarian cancer syndrome
+2 more
GUncertain significance
BRCA2
Single nucleotide variant
(synonymous variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GLikely benign
BRCA2
(W31L)
Single nucleotide variant
(missense variant)
Breast and/or ovarian cancer
+3 more
GUncertain significance
BRCA2
Single nucleotide variant
(splice donor variant +1 more)
not provided
+4 more
GPathogenic/Likely pathogenic
BRCA2
Deletion
(frameshift variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GPathogenic
BRCA2
(W3106*)
Single nucleotide variant
(nonsense)
Breast-ovarian cancer, familial, susceptibility to, 2
GPathogenic
BRCA2
Deletion
(frameshift variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GPathogenic
BRCA2
Deletion
Breast neoplasm
GPathogenic
BRCA2
Deletion
(frameshift variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GPathogenic
BRCA2
(Q1736*)
Single nucleotide variant
(nonsense)
Breast-ovarian cancer, familial, susceptibility to, 2
GPathogenic
BRCA2
(S1001fs)
Deletion
(frameshift variant)
Breast neoplasm
GPathogenic
BRCA2
(C1348fs)
Deletion
(frameshift variant)
Breast neoplasm
GPathogenic
BRCA2
Deletion
(frameshift variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GPathogenic
BRCA2
(H2178fs)
Duplication
(frameshift variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GPathogenic
BRCA2
(Q397fs)
Deletion
(frameshift variant)
Breast neoplasm
GPathogenic
BRCA2
Deletion
(frameshift variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GPathogenic
BRCA1
(I1808fs +3 more)
Deletion
(frameshift variant +2 more)
Breast neoplasm
GUncertain significance
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GConflicting classifications of pathogenicity
BRCA1
Single nucleotide variant
(synonymous variant)
Breast neoplasm
GUncertain significance
BRCA1
(S1387P +48 more)
Single nucleotide variant
(missense variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
+5 more
GConflicting classifications of pathogenicity
BRCA1
Single nucleotide variant
(synonymous variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
BRCA1
(S1024T +20 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+2 more
GConflicting classifications of pathogenicity
BRCA1
(K607E +20 more)
Single nucleotide variant
(missense variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
+3 more
GConflicting classifications of pathogenicity
BRCA1
Single nucleotide variant
(synonymous variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
BRCA1
(R756S +20 more)
Single nucleotide variant
(missense variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
+4 more
GConflicting classifications of pathogenicity
BRCA1
(C64W +1 more)
Single nucleotide variant
(missense variant)
Breast-ovarian cancer, familial, susceptibility to, 1
+2 more
GPathogenic/Likely pathogenic
BRCA1
Single nucleotide variant
(splice acceptor variant +1 more)
Breast neoplasm
+3 more
GPathogenic
BRCA1
Deletion
Breast neoplasm
GPathogenic
BRCA1
(F1524fs +3 more)
Deletion
(frameshift variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(E482fs +3 more)
Deletion
(frameshift variant +1 more)
Breast neoplasm
GPathogenic
BRCA1, LOC126862571
(E1310fs +21 more)
Insertion
(frameshift variant +1 more)
Breast neoplasm
GPathogenic
BRCA1
(L857* +20 more)
Single nucleotide variant
(nonsense +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(D853fs +20 more)
Insertion
(frameshift variant +1 more)
Breast neoplasm
GPathogenic
BRCA1
(S434fs +20 more)
Duplication
(frameshift variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1, LOC126862571
(Q1226fs +21 more)
Deletion
(frameshift variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(Q127fs +1 more)
Deletion
(frameshift variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
Deletion
(nonsense +3 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA2
Single nucleotide variant
(synonymous variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GLikely benign
BRCA2
Single nucleotide variant
(synonymous variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GBenign
BRCA2
Single nucleotide variant
(synonymous variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GBenign
BRCA2
Single nucleotide variant
(synonymous variant)
BRCA2-related cancer predisposition
GBenign
BRCA2
Deletion
(nonsense)
Breast-ovarian cancer, familial, susceptibility to, 2
GPathogenic
BRCA2
(E1895K)
Single nucleotide variant
(missense variant)
Hereditary breast ovarian cancer syndrome
+6 more
GConflicting classifications of pathogenicity
BRCA1
(K608del +20 more)
Deletion
(inframe_indel +2 more)
not provided
+5 more
GConflicting classifications of pathogenicity
BRCA2
(D1864N)
Single nucleotide variant
(missense variant)
Breast-ovarian cancer, familial, susceptibility to, 2
+4 more
GConflicting classifications of pathogenicity
BRCA2
Single nucleotide variant
(synonymous variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GLikely benign
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GBenign
BRCA2
(I729T)
Single nucleotide variant
(missense variant)
Familial cancer of breast
+13 more
GConflicting classifications of pathogenicity
BRCA2
(H523R)
Single nucleotide variant
(missense variant)
Breast-ovarian cancer, familial, susceptibility to, 2
+7 more
GConflicting classifications of pathogenicity
BRCA2
(K1636E)
Single nucleotide variant
(missense variant)
Breast neoplasm
+3 more
GConflicting classifications of pathogenicity
BRCA2
(R118C)
Single nucleotide variant
(missense variant)
not specified
+6 more
GConflicting classifications of pathogenicity
BRCA2
(E2878K)
Single nucleotide variant
(missense variant)
Breast neoplasm
+2 more
GPathogenic/Likely pathogenic
BRCA1
Deletion
(intron variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(G275D +19 more)
Single nucleotide variant
(missense variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GBenign
BRCA1
(R1835Q +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+5 more
GConflicting classifications of pathogenicity
BRCA1
(R1835* +80 more)
Single nucleotide variant
(nonsense +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
Deletion
(splice acceptor variant)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(K1690Q +77 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+8 more
GConflicting classifications of pathogenicity
BRCA1
(K1601* +77 more)
Single nucleotide variant
(nonsense +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(S1596L +77 more)
Single nucleotide variant
(missense variant +1 more)
Breast neoplasm
GUncertain significance
BRCA1
(S1389N +48 more)
Single nucleotide variant
(missense variant +1 more)
not specified
+4 more
GConflicting classifications of pathogenicity
BRCA1, LOC126862571
(P1150S +21 more)
Single nucleotide variant
(missense variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GBenign
BRCA1
(Q858* +20 more)
Single nucleotide variant
(nonsense +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(T796I +20 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary breast ovarian cancer syndrome
+4 more
GConflicting classifications of pathogenicity
BRCA1
(R762S +20 more)
Single nucleotide variant
(missense variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GBenign
BRCA1
Single nucleotide variant
(splice acceptor variant +1 more)
Breast neoplasm
+3 more
GPathogenic
BRCA1
(Q687* +20 more)
Single nucleotide variant
(nonsense +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA2
(R3128*)
Single nucleotide variant
(nonsense)
Breast-ovarian cancer, familial, susceptibility to, 2
GPathogenic
BRCA2
(N2591S)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
BRCA2
(G2508S)
Single nucleotide variant
(missense variant)
Breast-ovarian cancer, familial, susceptibility to, 2
+8 more
GConflicting classifications of pathogenicity
BRCA2
Deletion
(frameshift variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GPathogenic
BRCA2
(E215del)
Microsatellite
(inframe_deletion)
Familial cancer of breast
+5 more
GUncertain significance
BRCA2
(V2050I)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+12 more
GConflicting classifications of pathogenicity
BRCA2
Deletion
(frameshift variant)
Breast-ovarian cancer, familial, susceptibility to, 2
GPathogenic
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