Conserved Protein Domain Family
LIG3_BRCT

?
pfam16759: LIG3_BRCT 
DNA ligase 3 BRCT domain
The BRCT domain of DNA ligase 3 (LIG3) binds to the C-terminal BRCT domain of the scaffolding protein X-ray repair cross-complementing protein 1 (XRCC1) and mediates homo- and heterodimerization.
Statistics
?
PSSM-Id: 465260
Aligned: 16 rows
Threshold Bit Score: 91.6614
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_001943689  779 RLPDLFTGIRVVVPDSI-SKNT-FL-RYFIAYGGTPLNSSNELA-------PTHVIVQkKehnrssekpmkeEKKEKKKS 848 
Q1RL58        781 FLNDIFLGVKIFIPTDV-EKRK-KMeRHILAFNGDVLGNDQFKE-------ATHIVQC-D------------SVKVADIP 838  vase tunicate
4_pfamImport    1 FLKDTFEGVKIFIPNDV-QNRS-KMvRYIKANNGDVLKENELKL-------ATHVVQS-D------------SVKRLDIS 58  
EEN69839      848 VLPDVFCGIKLFLPDTV-ENYA-LLrRYFVAYDGDIVQDYAMSQ-------ATHVVED-P------------EQKNMNGK 905 
1_pfamImport    1 VLLDIFTGVRLYLPPST-PDFS-RLrRYFVAFDGDLPQAKQLDR-------A----AEqD-------------------- 47  
3_pfamImport    1 TLLDVFSGVKLFLPVSV-QDFH-KLrRYFVAYDGDVVQDYEVAT-------ATHTLAE-P-----------------EDD 53  
EEB12512      807 PLPNIFTGCVIQIPKEY-KNYD-LLrRYLIAYDGKLYDPEKETSvengknkVTHVIHLnKvg--------kiVKNEKYWD 876 
EFC36317      824 SLCDLFTDMVMYIHKDV-PALK-MHtRYIIAFDG-IVESSFSDD-------ITHIITSsSrit-------peIAKLVSEN 886 
EGD81001     1151 PLKNVFHGVTCFISDAV-PDYS-KAyRYGTAFGAELVN-AMGGD-------VTHVVVPdLdvdkw--daatkSAVSMASS 1218
KJE95709     1227 aLPDTFVGTNILLSPQLsPDVKrRLqRYIVAYGGTIVKPAELDL-------CTHVVVPsLd-----------SAASDRDN 1288
XP_001943689  849 LNATAVCAQWFWDSIRKG 866 
Q1RL58        839 ISASLVTASHVWECIKNK 856  vase tunicate
4_pfamImport   59 SEALSVTSKYVWECIQNE 76  
EEN69839      906 TDAQLVTVDWLWQCIKRK 923 
1_pfamImport   48 -----CLLRILPKALSSP 60  
3_pfamImport   54 SQAERVSPDWIWECIRKR 71  
EEB12512      877 KGVRHVHVNWIWNSIKLL 894 
EFC36317      887 PQVNVVSSEWIWHSINTS 904 
EGD81001     1219 TGARVVTAKWLWDSIKRR 1236
KJE95709     1289 GNAPAVLPSWIDACIAAG 1306
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap