3M8V,3FKC


Conserved Protein Domain Family
BTB_POZ_ZBTB33_KAISO
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cd18219: BTB_POZ_ZBTB33_KAISO 
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BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kaiso
Kaiso, also called zinc finger and BTB domain-containing protein 33 (ZBTB33), is a DNA methylation-dependent transcriptional repressor that binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3'. It also binds to the non-methylated consensus sequence 5'-CTGCNA-3', also known as the consensus kaiso binding site (KBS). It contains a BTB/POZ domain, a common protein-protein interaction motif of about 100 amino acids.
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Statistics
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PSSM-Id: 349528
Aligned: 8 rows
Threshold Bit Score: 191.198
Created: 12-Sep-2017
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3M8V_A        13 DIQYSGSLLNSLNEQRghGLFCDVTVIVEDRKFRAHKNILSASSTYFHQLFS------VAGQVVELSFIRAEIFAEILNY 86  human
3FKC_A        11 DIQYSGSLLNSLNEQRghGLFCDVTVIVEDRKFRAHKNILSASSTYFHQLFS------VAGQVVELSFIRAEIFAEILNY 84  human
Q8UVQ4        11 DTQYSGILLNALNDQRiqGLYCDVTVIVEDRKFRAHRNILSACSTYFHQLFS------VAGQVVELNFVKADIFAEILNY 84  African clawed ...
Q86T24        11 DIQYSGSLLNSLNEQRghGLFCDVTVIVEDRKFRAHKNILSASSTYFHQLFS------VAGQVVELSFIRAEIFAEILNY 84  human
XP_006003912  11 DTQYSGTLLKSLNEQRalGLFCDVTIIVEDRKFRAHKNVLCASSTYFHQLFS------VAGQVIELNFLRADIFAEILNY 84  coelacanth
NP_001093478  11 DTQYPGSLLKNINDERhnGLFCDVTIVVQDRKFRAHKCVLSASSTYFRQLFS------VAGKVVELNFIKADIFDMVLNY 84  zebrafish
NP_001073197  11 DTQYSSSLLQSLNEQRghGLFCDVTVIVEDRKFRAHRNILSASSTYFHQLLS------VAGQVVELSFVRADIFAEILNY 84  chicken
XP_007891391  11 DAQHSGTLLKSLNEQRaqGLFCDIAIIVEDRKFRAHKNVLSSASTYFHQLFCidgasnVYGQVLELNFIRAEVFAEVLNF 90  elephant shark

3M8V_A        87 IYSSKIVRVRsDLLDELIKSGQLLGVKFIAEL 118 human
3FKC_A        85 IYSSKIVRVRsDLLDELIKSGQLLGVKFIAAL 116 human
Q8UVQ4        85 IYSSKIVRVRcDMLEELIKSGKLLGVPFIAEL 116 African clawed frog
Q86T24        85 IYSSKIVRVRsDLLDELIKSGQLLGVKFIAEL 116 human
XP_006003912  85 IYSSKLVRVRsDLLEELIKSGQTLGVKFIAEL 116 coelacanth
NP_001093478  85 IYTSQMFRVRsDRLEDLINAGQILGVTFIANL 116 zebrafish
NP_001073197  85 MYSSKIISVRaDLIDELIKSGQQLGVKFLADL 116 chicken
XP_007891391  91 IYSSKLVRVDaLLVSELIQAGQALGLKFLADL 122 elephant shark
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