Conserved Protein Domain Family
PTZ00435

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PTZ00435: PTZ00435 
isocitrate dehydrogenase; Provisional
Statistics
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PSSM-Id: 240417
Aligned: 31 rows
Threshold Bit Score: 710.604
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
294899817   1 MTFSKIHVENPVVELDGDEMTRIIWAWIKEKLILPYLDIDIKYYDLSIEHRDATDDQVTVDAANAIKEYNVGIKCATITP 80 
71029224   55 NLKNKIVVKNPVVEIDGDEMTRIMWDKVKNKLIFPHLDLDLKYFDLSIQQRDSTDDKVTLDAAAAIQKYGVGVKCATITP 134
84997081   55 NLKNKIVVKNSIVEIDGDEMTKIMWDKVKKKLILPHVDLDLKYFDLSIQHRDSTDDKVTLDAAAAIQKHGVGVKCATITP 134
124513630  28 NICGKINVENPIVELDGDEMTRIIWKDIKEKLILPYVNLKIKYFDLSIENRDKTNDQVTIEAAEEIKKTSVGIKCATITP 107
156088897  42 STMAKIQVKNPIVELDGDEMTRVMWSSVKEKLILPYVDIPLLYYDLSLPNRDATDDKVTFEAAEAIKQVGIGVKCATITP 121
156096404  28 NIHGKVKVANPVVELDGDEMTKIIWKEIKEKLILPYLDLNIKYFDLSIENRDKTNDQVTLEAAEEIKKSSVGIKCATITP 107
221058503  28 NICGKVKVQNPVVELDGDEMTKIIWKDIKEKLILPYLDLNIKYFDLSIENRDKTNDQVTLEAAEEIKKSSVGIKCATITP 107
237830457  93 NLEGKIHVANPVVEMDGDEMTRILWAWIKEKLLFPYVEIPLEYYDLSVTNRDQTEDKVTLEAAEAIKKCHVGIKCATITP 172
237838915 177 SGFQRIKVDQPVVEMDGDEMARVIWAMIKEKLILPYLDIPLMYYDLSIQHRDKTDDQVTIDAALAIKRHGVGVKCATITP 256
294938720  13 VEYERIRVDNPIVELDGDEMTRIVWQMIKDKLIFPFLDMDIDYYDLSLTSRDKTNDEITIKAAKAILKYNVGVKCATITP 92 
294899817  81 DEARVKEFNLKKMWRSPNGTIRNILDGTIFRAPILCKNVPRLVPSWTHPIVIGRHGHGDQYKAEDrVVKC-AGKFTMTFT 159
71029224  135 DEARLKEFNLKRMYKSPNGTIRNILDGTVFRVPIITKSVPLLVPGWKKPIVIGRHAFGDQYNCQDfVVTE-PGKLELRFT 213
84997081  135 DEARVKEFNLKRMYKSPNGTIRNILDGTVFRVPIITKSVPLLVPGWKKPIVIGRHAFGDQYNCQDfVVSE-PGKLELRFT 213
124513630 108 DAARVKEFNLKEMWKSPNGTIRNILDGTVFRTPILIKNIPKLVPNWKKPIVIGRHAYADQYKQKSlKIEK-SGKFEIVFT 186
156088897 122 DEARLKEFGLKRMYRSPNGTIRNILDGTVFRSPILTKTVPAYIPGWKKPIIIGRHAFGDQYNATDiKIPG-AGTLELVFT 200
156096404 108 DAARVKEFNLKKMWKSPNGTIRNILDGTVFRAPILIKNIPRLIPNWKKPIVIGRHAYADQYKQKSlKIEK-SGKFEIVFT 186
221058503 108 DAARVKEFNLKQMWKSPNGTIRNILDGTVFRAPILIKNIPRLIPNWKKPIIIGRHAYADQYKQKSlKIDK-SGKFEIVFT 186
237830457 173 DEGRVKEFNLKKMWKSPNGTIRNILDGTVFRAPILISNVPRLVPGWKKPIVIGRHAYGDQYKAESlVCDG-PGDFTISFT 251
237838915 257 DEQRVKEFNLKKMWKSPNATIRNTLDGTIFRAPILMKNVPRLVPSWTKPIIIGRHAHADQYKALDfTVDK-PGRFVMSFI 335
294938720  93 DAARVEEFKLKKMWKSPNGTIRNILDGTVFRAPIIIRNIPRYVPGWEYPIVIGRHAHADQYKCEQfQTDNiPGIVDLVFH 172
294899817 160 PDDGSEPLNVDVFHF--DEdGGVIQGMYNTDKSIYGFARSCFIYALDMKMPLYLSTKNTILKKYDGRFKDIFQEMYDKEY 237
71029224  214 PE-GGEPKNVVVHEF--KG-PGVAIGMFNLDKSILGFARASFNYALSQNLPLYFSTKNTILKYYDGRFKDLFQKVYDEEF 289
84997081  214 PE-GGEPKSVVVHDF--KG-SGVAIGMFNLDKSILGFARASFNYALSQNMPLYFSSKNTILKYYDGRFKDLFQKVYDEEF 289
124513630 187 PDDNSQVLRETVFHF--KS-PGVCLGMYNTEESIRNFALSCFQYALDLKMPVYMSTKSTILKIYDGLFKDIFDEIYEKQF 263
156088897 201 PADGGPTQAYKVTDF--KG-PGVALSMFNVDQSIRGFARACFTYALDVKMPLYMSTKNTILKSYDGRFKDIFQQMYDDEF 277
156096404 187 PDDNSQVMREEIFHF--KS-PGVCLGMYNTEESITNFALSCFQYALDLKMPVYMSTKSTILKIYDGLFMEIFQKIYDQKF 263
221058503 187 PDDKSEVMREEIFHF--KS-PGVCLGMYNTEESITNFALSCFQYALDLKMPVYMSTKSTILKIYDGLFMEIFQKIYDEKF 263
237830457 252 PA-GGSRVEKKVFSF--SG-PGVMLGMYNTEDSIRGFALSSFKFALQQNMPLYLSTKNTILKQYDGMFKDIFQSYYDEQF 327
237838915 336 PADKSNPEVHEVYEF--KG-GGVALGMYNTDASIKGFAHSCFQYALDQKMPLYLSTKNTVLKKYDGRFKDIFQTIYEKEY 412
294938720 173 PSDGSASKTVRLFEFkeKDeGGVVMGMYNTKRSIESFARCCFTYALGQGMPLYFSSKNTILKAYDGMFKDIFQQLYVEEY 252
294899817 238 KVKFEELGIWYEHRLIDDMVAQAIKSSGGFVWACKNYDGDVQSDIVAQGYGSLGMMTSVLVCPDGKTIEAEAAHGTVTRH 317
71029224  290 KAKFEEKGLTYQHRLIDDMVAFALKSEGGFVWACKNYDGDVQSDIVAQAYGSLGLMSSVLFSSDGKCFLSEAAHGTVTRH 369
84997081  290 KTKFEEKGLTYQHRLIDDMVAFALKSEGGFVWACKNYDGDVQSDIVAQAYGSLGLMSSVLFSSDGKCFLSEAAHGTVTRH 369
124513630 264 KKSFEQHNLWYEHKLIDDMVAQVLKSEGGFLWACKNYDGDIQSDAVAQGYGSLGLMSSVLLCPDGVTCVSEAAHGTVTRH 343
156088897 278 RPLFEAAGIFYEHRLIDDMVAYACKSEGGFVWACKNYDGDVQSDIVSQAYGSLALMSSVLYSSDGKSFLAEAAHGTVTRH 357
156096404 264 RNLFEQHNLWYEHKLIDDMVAQVLKSEGGFVWACKNYDGDIQSDAVAQGYGSLGLMSSILVCPDGVTCVSEAAHGTVTRH 343
221058503 264 RTLFEKNNLWYEHKLIDDMVAQVLKSEGGFVWACKNYDGDIQSDAVAQGYGSLGLMSSILMCPDGVTCVSEAAHGTVTRH 343
237830457 328 KPLFEKQGIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDIVAQGYGSLGLMTSILVCPDGKTVVSEAAHGTVTRH 407
237838915 413 KQKFEEAGLWYEHRLIDDMVAQAIKSSGGFVWACKNYDGDVQSDVVAQGYGSLGLMTSVLVCPDGKTIEAEAAHGTVTRH 492
294938720 253 KSAFDKAGLWYEHRLIDDMVAQAIKSKGGFVWACKNYDGDVQSDIVAQGYGSLGLMTSILVCPDGKTVLSEAAHGTVTRH 332
294899817 318 YRQHQKGLKTSTNPIASIFAWTRGLSHRAKLDGNDQLMKFAHALEEVCVESIENGAMTKDLALCIYNCqpSELKETQYLT 397
71029224  370 YRQYQKGVVTSTNPVAIIVAWAKALERRGKLDANQELVQFAQKLERSCVEAIDAGFMTKDLALARN----PKATENDYLN 445
84997081  370 YRQYQKGLVTSTNPVAIIVAWAKALERRGNLDQNLELVQFAQKLERSCVDAIDSGFMTKDLALARN----PKATENDYLN 445
124513630 344 YRAYQKGEKTSTNPIASIFAWTKGLEHRAKLDKNDNLKQFCYALEKACIETVEDGLMSKDLAGCIKGI--KNVTEKDYIF 421
156088897 358 FRVHQKGGSTSTNSIATIVAWARALEKRGLADGNDALVEFGRKLERAPVEAVDAGYYTKDLAIAIHGP-----QATDYLD 432
156096404 344 YRCHQRGEKTSTNPIASIFAWTRGLQHRAKLDQNQPLQLFCYALERACIETVEDGLMPKDLAACIKGL--KNVTEKDYLF 421
221058503 344 YRCHQRGEKTSTNPIASIFAWTRGLQHRAKLDKNQPLQLFCYALESACIETVEDGLMPKDLAACIKGL--KNVTEKDYLF 421
237830457 408 YRQHQKGQKTSTNPIASIFAWTRGLAHRAKLDGNDRLGQFCLALEHACIQTVENGAMPKDLALCVKGA--DKVTASDYLT 485
237838915 493 YRQYQKGIKTSTNPIASIYAWTRSLGHRAKLDNNQKLKEFVEALEDACVETVEAGFMTKDLALAIKG---DKLTDRDYLC 569
294938720 333 FRAYQRGEKTSTNPIASIFAWSRALNQRAILDDNSRLKHFAQALEEACIESVEAGYMSKDLAICVAGT--SKVSSEQYLT 410
294899817 398 SEVFMDVLAKNLEPKMSL 415
71029224  446 TDQYIDKVLEFLHS---- 459
84997081  446 TDQYIDKVLEFLHS---- 459
124513630 422 TQDLINAINEKLKLKILQ 439
156088897 433 TESFMDKVKEFLEK---- 446
156096404 422 TDDFIDAINEKLKLKLLA 439
221058503 422 TDDFINAINEKLKLKLLA 439
237830457 486 TEEFMDAISDTLKMNLIT 503
237838915 570 TEDFMDKLARVAERKLLE 587
294938720 411 SEDLIDYFSERLKVKLAK 428
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