2XBZ


Conserved Protein Domain Family
7TMR-DISMED2

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pfam07696: 7TMR-DISMED2 
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7TMR-DISM extracellular 2
This entry represents one of two distinct types of extracellular domain found in the 7TM-DISM (7TM Receptors with Diverse Intracellular Signalling Modules) bacterial transmembrane proteins. It is possible that this domain adopts a jelly roll fold and acts as a receptor for carbohydrates and their derivatives. It can also recognize Ca(II) (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Statistics
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PSSM-Id: 429601
Aligned: 205 rows
Threshold Bit Score: 44.637
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2XBZ_B                  38 LLRDESAQLRIADVlqrk----eqfRPLAKRSFIFPA-----SPQAVWLQVQLP-------------------AQKVPSW 89   Pseu...
Q11KB8                  37 IHRDQGENFQVSTApgadgivrrie-----------veaqdsrstgDWAVFALAn------------------TTDEQLD 87   Chel...
jgi:Oant_0596           52 LLRNKGESVQVSTApgpdgivrrie----------vqadqnskasgDWAAFSIAn------------------PTDEQID 103 
WP_015331712            40 ILTDTTGNLTIGQVtspaf--qgrfRPSRQVIINVGF-----SDRIHWLRFSVD--------------------NPTPDK 92   Fibr...
CCG99712                73 YLTETGGPLTLEQVrrq------pmMPVEADQIDFGH-----TDRVHWLRFSISn------------------GVAAQQP 123 
WP_025282634            57 VYMDTARRTTPEALldrd---ppdfVELDSRSFNQGM-----SPGVLWVAFALQ--------------------ELDARP 108  Ecto...
CCH02980                35 LYIDTTRRQALPDVqlm------pfRPVGTGVPNIGYtgnqqSVVPFWLRFQVQn------------------ATQRPAR 90  
WP_015330825            56 WLADSSRRLTLHDVispav--sprfRLVNTQYPNAGY-----TLDDYWLRVRIRvv----------------gPNQKPGE 112  Fibr...
PRJNA63271:OPIT5_27785  51 FLRDPGGRATLDDIrsgsp--asgwQPARGGIPNFGY-----TADAIWLRFRVSyp---------------enGDRVSRR 108 
PRJNA63271:OPIT5_20905  98 VLRDPGGKETFASVsdvsraagwqaVPAAGRIPGFGY-----TDDVLWLRARISappsadrassapaslpsspPSAASRR 172 
2XBZ_B                  90 -------LWIFAPRVQYLDYYLVQdgqlv------rdqhTGESRP--FqeRPl-------pSRS----YLFSLPV---DG 140  Pseu...
Q11KB8                  88 rlivaphFRLVGSGIIWPDLgsqria--------aitpsEGFALD----------------RQPssdaDEFLVTL---NP 140  Chel...
jgi:Oant_0596          104 rlivaphFRLVGSGVIWPDLgspria--------sitpsEGFALD----------------RQPsadaDVFRITL---NP 156 
WP_015331712            93 l-----lLEVAQAFLPITELYYQNeagkt------vrltAGFRIPvdQkiRK---------HHY----QVF--PI---PP 143  Fibr...
CCG99712               124 vw----vLRVMSLSSTVCDLYLVDp--------------TGRV-------RQwpagirfsfAQRpfdaLTFDFPLrltDP 178 
WP_025282634           109 r-----lLSLDNPLFDSVTLFaq--------------eeGGQWRE-----VPrhqavawdqQRRpawrHVF--HIe-aDS 161  Ecto...
CCH02980                91 l-----yAAVNFWCYESLQLFVVDrkndsl---ltssipMGWRTA--VsvRPv-------hNRY----YYFPFSV---PP 146 
WP_015330825           113 il----fLENAFPIATSVDLFVLDstgrvlethrstscsLGDRREv--------------pHPH----FVFTMPV---RP 167  Fibr...
PRJNA63271:OPIT5_27785 109 w-----lVELESTRFDEIDWFLLEnghlv------rsesAGHLRPpvrg--------gghaGRQprypVLMLDEL---EP 166 
PRJNA63271:OPIT5_20905 173 w-----mLELASTRFDMIDWFVVEngrlv------ftaaGGNLRP------PsgnipgagnPRYpaipLDL-------TP 228 
2XBZ_B                 141 KPX-TLYVRXTSN-HPLXAW 158  Pseudomonas aeruginosa
Q11KB8                 141 GTVvTFVAELSSP---NLPQ 157  Chelativorans sp. BNC1
jgi:Oant_0596          157 GSVvTFVAELSSH---NLPQ 173 
WP_015331712           144 GRH-TYFVRLLAH--SQPVP 160  Fibrella aestuarina
CCG99712               179 RPY-TAYLRLAGV-NSQQYT 196 
WP_025282634           162 PAS-RYLLRVETG-QNLRFH 179  Ectothiorhodospira haloalkaliphila
CCH02980               147 GGDyMIYLRVNKArGTQLVP 166 
WP_015330825           168 GQTlTLYVHSRNEmGLQYLP 187  Fibrella aestuarina
PRJNA63271:OPIT5_27785 167 GRTfEVYLRLRTE-MTFFTP 185 
PRJNA63271:OPIT5_20905 229 ERSvDVYLRLHTE-GSAFVP 247 
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