2L2N,2N3F,3ADG


Conserved Protein Domain Family
DSRM_AtDRB-like_rpt1

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cd19907: DSRM_AtDRB-like_rpt1 
first double-stranded RNA binding motif of Arabidopsis thaliana double-stranded RNA-binding proteins (AtDRBs)and similar proteins
This family includes a group of Arabidopsis thaliana double-stranded RNA-binding proteins (AtDRB1-5). They bind double-stranded RNA (dsRNA) and may be involved in RNA-mediated silencing. Members of this family contain two to three double-stranded RNA binding motifs (DSRMs). This model describes the first motif. DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Statistics
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PSSM-Id: 380736
Aligned: 12 rows
Threshold Bit Score: 102.554
Created: 31-Oct-2018
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
putative RNA
Conserved site includes 19 residues -Click on image for an interactive view with Cn3D
Feature 1:putative RNA binding site [nucleic acid binding site]
Evidence:
  • Comment:Based on structure evidence that Homo sapiens TARBP2 (5N8L) binds siRNA.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1         # ##  ##    ##        ##### #                 ####  ##           
2L2N_A     18 VFKSRLQEYAQKYkLPTPVYEIVKEGPSHKSLFQSTVILDGVRYNSLPGFFNRKAAEQSAAEVALRELA 86  thale cress
2N3F_A      4 VYKGQLQAYALQHnLELPVYANEREGPPHAPRFRCNVTFCGQTFQSSEFFPTLKSAEHAAAKIAVASLT 72  thale cress
3ADG_A      4 VFKSRLQEYAQKYkLPTPVYEIVKEGPSHKSLFQSTVILDGVRYNSLPGFFNRKAAEQSAAEVALRELA 72  thale cress
O04492     15 VFKSRLQEYAQKYkLPTPVYEIVKEGPSHKSLFQSTVILDGVRYNSLPGFFNRKAAEQSAAEVALRELA 83  thale cress
Q9SKN2      1 MYKNQLQELAQRScFNLPSYTCIREGPDHAPRFKATVNFNGEIFESPQYCSTLRQAEHSAAEVALNALS 69  thale cress
Q9LJF5      1 MYKNQLQELAQRScFSLPSYTCTREGPDHAPRFKASVNFNGEIFESPTYCSTLRQAEHSAAEVALSALS 69  thale cress
ABR16750    1 MYKNQLQELAQRNcFNLPLYGCIRKGPDHAPRFRATVNFNGEIFESPNYCSTLRQAELVAAEVAVNTLS 69  Sitka spruce
EFJ21698    1 MYKSQLQEFAQKSgWTVPQYDSIKQGLPHLPRFQASVEVNGVKYESEDGFPNLKAAEHSAAKKALDSLT 69  Selaginella moellendorffii
Q8GY79      1 MYKNQLQELAQRScFNLPSYTCIREGPDHAPRFKASVNFNGEIFESPTYCSTLRQAEHAAAEVSLNVLS 69  thale cress
Q8H1D4      4 VYKGQLQAYALQHnLELPVYANEREGPPHAPRFRCNVTFCGQTFQSSEFFPTLKSAEHAAAKIAVASLT 72  thale cress
PNR36381   11 MYKNQLQELAQRScINLPAYACIREGPDHAPRFKATVSFNGEIFESPNYCNTLRQAEHAAAEVALNTLS 79  Physcomitrella patens
CDM87075   88 PYKWQLQDYAQKRqKDLPLYHTIQSGPLHQPMFRSTVTIDGRTFENPQDHNTKKKAESAAAAAALMALA 156 bread wheat

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